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The map label for this gene is aroA [H]

Identifier: 229000869

GI number: 229000869

Start: 616159

End: 617493

Strand: Reverse

Name: aroA [H]

Synonym: NATL1_06701

Alternate gene names: 229000869

Gene position: 617493-616159 (Counterclockwise)

Preceding gene: 124025380

Following gene: 124025378

Centisome position: 33.11

GC content: 40.45

Gene sequence:

>1335_bases
TTGAAAGCTCCCACTAAAGATCAGTCTTTAAGAAACCTTCAAAAAGGAGGGGAGCTCTATGGAAAAGTGAAAGTACCTGG
AGACAAGTCAATCTCACACCGTGCACTACTTTTTGGGGCTATTGCTAAGGGGAAAACACTAATTGAGGGCCTTTTACCTG
CTGAAGATCCATTAAGTACTGCTGAATGCCTTAGGTCAATGGGCGTAAAGATTAGTCCAATCAAGAAAGGAGACATTATT
GAAATTGAAGGCGTTGGATTAAATGGCCTCCAGGAGCCACAAGATATTTTGAACTGCGGAAATTCAGGAACAACTATGAG
ATTAATAATGGGATTATTAGCCGGTCAAAAAGATCATCATTTCATCCTCACAGGCGATAAATCACTTAGAAATAGGCCGA
TGAAAAGAGTAGGACAGCCGTTAAAAATGATGGGGGCTAAAGTTTTCGGAAGATGCGGTGGAGACTTGGCTCCTCTATCG
ATTATTGGGAATAAATTAAGAGGTGCCGTAATTGGTACACCAGTAGCAAGTGCTCAGATAAAATCTGCAATCCTACTAGC
TGCTCTTAATGCAGAAGGCTCAACGACGGTTATTGAACCCGCCAGATCAAGAGATCATAGCGAGAGAATGCTAAAAGCCT
TCGGAGCTAATCTAGAGGTTGGTGGAGAGATGGGTAGACATATAACTGTATCCCCTGGTAAAGATCTAAAAGGTCAATCA
ATTATTGTTCCTGGAGATATTAGTTCCGCTGCATTTTGGCTCGTTGCAGGTAGCATCATACCCGGATCAGAGTTGGTTGT
AGAAAATGTTGGTCTAAATCCAACAAGGACTGGAATACTTGACGTATTAGAAGCAATGGAAGCAAATATCAACGTAATAA
ACAAAAGAGATGTAGCCGGTGAACCTGTCGGAGATATTGAAGTTTTCTACAAAGAAAACTTAAAACCATTTAAAATTGAC
GATGAGATAATGCCACGGCTTGTTGACGAGATACCCATTTTATCCGTAGGAGCATGTTTTTGTAATGGTATCAGTCAAAT
AAAAGGAGCAAGTGAGCTAAGAGTTAAAGAAACTGATCGATTAGCTGTAATGGCAAGGCAATTAAAAAGGATGGGAGCCA
GCGTAGATGAGCATCAAGATGGTCTAACTATCTATGGAGGAAAAAGCTTAGAAGGATGCGAACTTGATAGCGAGGATGAT
CACCGTATAGCCATGAGTTTAGCTATTGCATCAATAATGGCTAATTCTAATTCGACATTACGACGTAGTGAGGCTGCAGC
AATTTCATATCCTGATTTTTGGAGTGATCTTAAGAGACTTCAACAAAAAAATTAG

Upstream 100 bases:

>100_bases
TGTTATCGATGAATTAATGCGTCAAAAACAAATAAACAATTCATAAATCAGTAATAAAGCTTATCGAGAAATAAAATATA
AAAAAATATATTTTTTTTCA

Downstream 100 bases:

>100_bases
CTTTCTGAGAATTGGATGATTATAAAAAACATACGACAAGAGATGGGAGTTTAAGTCTTTATAGCTTGAGCTATAAAGAA
GGATTTCATGATAAGGACGG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKAPTKDQSLRNLQKGGELYGKVKVPGDKSISHRALLFGAIAKGKTLIEGLLPAEDPLSTAECLRSMGVKISPIKKGDII
EIEGVGLNGLQEPQDILNCGNSGTTMRLIMGLLAGQKDHHFILTGDKSLRNRPMKRVGQPLKMMGAKVFGRCGGDLAPLS
IIGNKLRGAVIGTPVASAQIKSAILLAALNAEGSTTVIEPARSRDHSERMLKAFGANLEVGGEMGRHITVSPGKDLKGQS
IIVPGDISSAAFWLVAGSIIPGSELVVENVGLNPTRTGILDVLEAMEANINVINKRDVAGEPVGDIEVFYKENLKPFKID
DEIMPRLVDEIPILSVGACFCNGISQIKGASELRVKETDRLAVMARQLKRMGASVDEHQDGLTIYGGKSLEGCELDSEDD
HRIAMSLAIASIMANSNSTLRRSEAAAISYPDFWSDLKRLQQKN

Sequences:

>Translated_444_residues
MKAPTKDQSLRNLQKGGELYGKVKVPGDKSISHRALLFGAIAKGKTLIEGLLPAEDPLSTAECLRSMGVKISPIKKGDII
EIEGVGLNGLQEPQDILNCGNSGTTMRLIMGLLAGQKDHHFILTGDKSLRNRPMKRVGQPLKMMGAKVFGRCGGDLAPLS
IIGNKLRGAVIGTPVASAQIKSAILLAALNAEGSTTVIEPARSRDHSERMLKAFGANLEVGGEMGRHITVSPGKDLKGQS
IIVPGDISSAAFWLVAGSIIPGSELVVENVGLNPTRTGILDVLEAMEANINVINKRDVAGEPVGDIEVFYKENLKPFKID
DEIMPRLVDEIPILSVGACFCNGISQIKGASELRVKETDRLAVMARQLKRMGASVDEHQDGLTIYGGKSLEGCELDSEDD
HRIAMSLAIASIMANSNSTLRRSEAAAISYPDFWSDLKRLQQKN
>Mature_444_residues
MKAPTKDQSLRNLQKGGELYGKVKVPGDKSISHRALLFGAIAKGKTLIEGLLPAEDPLSTAECLRSMGVKISPIKKGDII
EIEGVGLNGLQEPQDILNCGNSGTTMRLIMGLLAGQKDHHFILTGDKSLRNRPMKRVGQPLKMMGAKVFGRCGGDLAPLS
IIGNKLRGAVIGTPVASAQIKSAILLAALNAEGSTTVIEPARSRDHSERMLKAFGANLEVGGEMGRHITVSPGKDLKGQS
IIVPGDISSAAFWLVAGSIIPGSELVVENVGLNPTRTGILDVLEAMEANINVINKRDVAGEPVGDIEVFYKENLKPFKID
DEIMPRLVDEIPILSVGACFCNGISQIKGASELRVKETDRLAVMARQLKRMGASVDEHQDGLTIYGGKSLEGCELDSEDD
HRIAMSLAIASIMANSNSTLRRSEAAAISYPDFWSDLKRLQQKN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=440, Percent_Identity=29.0909090909091, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=462, Percent_Identity=27.0562770562771, Blast_Score=126, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 47576; Mature: 47576

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPTKDQSLRNLQKGGELYGKVKVPGDKSISHRALLFGAIAKGKTLIEGLLPAEDPLST
CCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCH
AECLRSMGVKISPIKKGDIIEIEGVGLNGLQEPQDILNCGNSGTTMRLIMGLLAGQKDHH
HHHHHHCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCE
FILTGDKSLRNRPMKRVGQPLKMMGAKVFGRCGGDLAPLSIIGNKLRGAVIGTPVASAQI
EEEECCHHHHCCCHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCHHHHH
KSAILLAALNAEGSTTVIEPARSRDHSERMLKAFGANLEVGGEMGRHITVSPGKDLKGQS
HHEEEEEEECCCCCEEEECCHHCCCHHHHHHHHHCCCCEECCCCCCEEEECCCCCCCCCE
IIVPGDISSAAFWLVAGSIIPGSELVVENVGLNPTRTGILDVLEAMEANINVINKRDVAG
EEECCCCCHHEEEHEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
EPVGDIEVFYKENLKPFKIDDEIMPRLVDEIPILSVGACFCNGISQIKGASELRVKETDR
CCCCCEEHHHHCCCCCEECCHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCEECHHHH
LAVMARQLKRMGASVDEHQDGLTIYGGKSLEGCELDSEDDHRIAMSLAIASIMANSNSTL
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
RRSEAAAISYPDFWSDLKRLQQKN
HHCCCCEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKAPTKDQSLRNLQKGGELYGKVKVPGDKSISHRALLFGAIAKGKTLIEGLLPAEDPLST
CCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCH
AECLRSMGVKISPIKKGDIIEIEGVGLNGLQEPQDILNCGNSGTTMRLIMGLLAGQKDHH
HHHHHHCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCE
FILTGDKSLRNRPMKRVGQPLKMMGAKVFGRCGGDLAPLSIIGNKLRGAVIGTPVASAQI
EEEECCHHHHCCCHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCHHHHH
KSAILLAALNAEGSTTVIEPARSRDHSERMLKAFGANLEVGGEMGRHITVSPGKDLKGQS
HHEEEEEEECCCCCEEEECCHHCCCHHHHHHHHHCCCCEECCCCCCEEEECCCCCCCCCE
IIVPGDISSAAFWLVAGSIIPGSELVVENVGLNPTRTGILDVLEAMEANINVINKRDVAG
EEECCCCCHHEEEHEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
EPVGDIEVFYKENLKPFKIDDEIMPRLVDEIPILSVGACFCNGISQIKGASELRVKETDR
CCCCCEEHHHHCCCCCEECCHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCEECHHHH
LAVMARQLKRMGASVDEHQDGLTIYGGKSLEGCELDSEDDHRIAMSLAIASIMANSNSTL
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
RRSEAAAISYPDFWSDLKRLQQKN
HHCCCCEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA