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The map label for this gene is coaD

Identifier: 227080442

GI number: 227080442

Start: 214261

End: 214755

Strand: Reverse

Name: coaD

Synonym: VCM66_0210

Alternate gene names: 227080442

Gene position: 214755-214261 (Counterclockwise)

Preceding gene: 227080444

Following gene: 227080435

Centisome position: 7.42

GC content: 49.09

Gene sequence:

>495_bases
GTGAGCCAAAAACGTCTTTCCCGAGTGATTTACCCTGGCACTTTTGACCCCATCACTAACGGTCATCTGGATTTGATTGA
GCGCGCCGCGCAAATGTTTGATGAAGTGATCATCGCCGTAGCCGCCAGCCCGAGTAAAAATACTCTGTTTACGCTCGAAG
AGCGCGTCGAGTTCGCGCGCCAAGTCACCTCACATCTGGATAACGTCAGCGCGAAAGGCTTTTCCGGATTGTTAGTTGAT
TTTGCCAAAGCCGAAAAAGCGAATGTATTGATCCGCGGCTTGCGTACCACAGTCGATTTTGAATACGAATTTGGTCTCAC
CAATATGTATCGCCGTTTAATGCCGGGCTTAGAGAGTGTGTTTTTAACGCCCGCCGAAGAGCACGCATTTATCTCGTCGA
CCTTAGTCCGGGAAGTGGCAATCCACGGCGGTAATGTGGATGAGTTTGTGCCCGCTATTGTCGCTAACGCTCTACATCAA
AAGAAAAAAATCTAG

Upstream 100 bases:

>100_bases
AAGGTGTGAAATTTTGCGTGCTCATCATACCGACTTCATAGGTAAATGTGAGGCTTTTTGTTAGGATGAGGCCACTTCCC
TGATTGATGAGTAACGGATT

Downstream 100 bases:

>100_bases
CGCTTCAAAGGGATGCAAGCTCACATCCCTCAATCCCCTTCCTACTTGAAGCTGCAGCGATGTTGGCTACCTGCAACTCT
AAGTCGTTTGGGTATATCAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSQKRLSRVIYPGTFDPITNGHLDLIERAAQMFDEVIIAVAASPSKNTLFTLEERVEFARQVTSHLDNVSAKGFSGLLVD
FAKAEKANVLIRGLRTTVDFEYEFGLTNMYRRLMPGLESVFLTPAEEHAFISSTLVREVAIHGGNVDEFVPAIVANALHQ
KKKI

Sequences:

>Translated_164_residues
MSQKRLSRVIYPGTFDPITNGHLDLIERAAQMFDEVIIAVAASPSKNTLFTLEERVEFARQVTSHLDNVSAKGFSGLLVD
FAKAEKANVLIRGLRTTVDFEYEFGLTNMYRRLMPGLESVFLTPAEEHAFISSTLVREVAIHGGNVDEFVPAIVANALHQ
KKKI
>Mature_163_residues
SQKRLSRVIYPGTFDPITNGHLDLIERAAQMFDEVIIAVAASPSKNTLFTLEERVEFARQVTSHLDNVSAKGFSGLLVDF
AKAEKANVLIRGLRTTVDFEYEFGLTNMYRRLMPGLESVFLTPAEEHAFISSTLVREVAIHGGNVDEFVPAIVANALHQK
KKI

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=154, Percent_Identity=61.6883116883117, Blast_Score=198, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_VIBC3 (A5F408)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F408
- SMR:   A5F408
- STRING:   A5F408
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2603
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   VCHO345073:VC0395_A2603-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18264; Mature: 18133

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKRLSRVIYPGTFDPITNGHLDLIERAAQMFDEVIIAVAASPSKNTLFTLEERVEFAR
CCHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
QVTSHLDNVSAKGFSGLLVDFAKAEKANVLIRGLRTTVDFEYEFGLTNMYRRLMPGLESV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCHHHE
FLTPAEEHAFISSTLVREVAIHGGNVDEFVPAIVANALHQKKKI
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQKRLSRVIYPGTFDPITNGHLDLIERAAQMFDEVIIAVAASPSKNTLFTLEERVEFAR
CHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
QVTSHLDNVSAKGFSGLLVDFAKAEKANVLIRGLRTTVDFEYEFGLTNMYRRLMPGLESV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCHHHE
FLTPAEEHAFISSTLVREVAIHGGNVDEFVPAIVANALHQKKKI
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA