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The map label for this gene is murA

Identifier: 226951021

GI number: 226951021

Start: 4079627

End: 4080880

Strand: Direct

Name: murA

Synonym: CLM_4058

Alternate gene names: 226951021

Gene position: 4079627-4080880 (Clockwise)

Preceding gene: 226951019

Following gene: 226951022

Centisome position: 98.18

GC content: 34.21

Gene sequence:

>1254_bases
ATGAGTAAATTAAAAATAACAGGAGGTAACCCCCTCTTTGGAAAAGTTGAAATTAGTGGAGCAAAAAATGCAGCAGTAGC
TATATTACCTGCTACTATTATGGCTAGCAAAGGAGTTTGTACTATAGAGAATACTCCAAATATTGAAGATGTACATTGTA
TTGAAAGAATTCTAAATGGATTGGGTTGCGAAATTAAAAGACAAAGCAATTCTATTTTACAAATAGATAGTACCAATATA
ACAAAAACAGATGCTAATACTGAAGATGTAAGAAAAATGAGAGCTTCTTATTATCTTATCGGAGCTTTATTAGGAAGGTT
TAAAAAAGCTAGAGTAGAATTACCTGGTGGATGTCCTATAGGTGTTAGACCTATAGATCAACACATTAAAGGTTTTGAAG
CTTTAGGAGCTCATGTCGAAATAGAACATGGTGCTGTAATTGTCAAAGCAGATAAATTAATAGGAACTAATATATTTTTT
GACGTTGTTAGCGTAGGCGCTACTATAAATGTGATGTTAGCTGCCACACTTGCTGAAGGCAATACTGTGCTAGAAAACGT
AGCAAAGGAACCTCACGTAGTAGATGTAGCTAATTTTTTAAATAGTATGGGAGCTAATATCAAAGGTGCTGGAACAGACA
TTATAAGAGTTACTGGTGTTAAAGAATTAAAAGGCTGTACTTATAGTGTAATACCTGATCAAATTGAAGCTGGTACATAT
ATGATAGCAACAGCTGCCTGCGGTGGAGAAGTTACAATAAATAACGTAATACCTAAACACTTAGAATCTATAACAGCAAA
ACTTATAGAAATGGGAGTAGATGTTATAGAAAATGGAGATTCTGTTACAGTAAAATCTAAAGGTAATTTTAAAGGCGCTA
ATATAAAAACTCAACCTTACCCAGGATTTCCAACGGATGTGCAACAACCAATGAGCACACTTTTAACTATTGCAAAAGGA
AGAAGTATTGTAAATGAAAGCATTTGGGAAAGTAGATTTAAACATGTAGATGAATTGAAGAAAATGGGAGCAAATATTAA
GGTAGAAGGTAGAACAGCCATTATAGATGGTGTACCTAAACTTACAGGAGCTATAGTAAAAGCTACGGATTTGAGAGCTG
GAGCTGCTATGGTAATTGCTGGATTATTAGCTGAAGGTGATACCGAAATTCTTGGTGTGGAGCATATAGATAGAGGATAC
CCAAATATTGAAAATAAATTTAGATCCTTAGGGGCTACTATAGTTAGACTATAG

Upstream 100 bases:

>100_bases
AAAATAATAAATAGTTATGATATAATATATTTTGTTACATAGGTTTGAAATTAACGATTAGTTTAAATATATAAATTCTA
AAGTAAGGATGGATGCGGGG

Downstream 100 bases:

>100_bases
TTAAGTTACAATTTAAAATTTTATTATGATTTTTTGTTCTCTTTATAGTGGTAGTAGTGGTAATTCCATATTTATATCCT
CTGAAAAATCAAAAATACTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNGLGCEIKRQSNSILQIDSTNI
TKTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGTNIFF
DVVSVGATINVMLAATLAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIEAGTY
MIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPYPGFPTDVQQPMSTLLTIAKG
RSIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHIDRGY
PNIENKFRSLGATIVRL

Sequences:

>Translated_417_residues
MSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNGLGCEIKRQSNSILQIDSTNI
TKTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGTNIFF
DVVSVGATINVMLAATLAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIEAGTY
MIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPYPGFPTDVQQPMSTLLTIAKG
RSIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHIDRGY
PNIENKFRSLGATIVRL
>Mature_416_residues
SKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNGLGCEIKRQSNSILQIDSTNIT
KTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPIGVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGTNIFFD
VVSVGATINVMLAATLAEGNTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIEAGTYM
IATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPYPGFPTDVQQPMSTLLTIAKGR
SIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPKLTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHIDRGYP
NIENKFRSLGATIVRL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=45.1073985680191, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_CLOB1 (A7FZC7)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385880.1
- STRING:   A7FZC7
- GeneID:   5397867
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3647
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   IDNIPDI
- ProtClustDB:   PRK09369
- BioCyc:   CBOT441770:CLB_3647-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44359; Mature: 44228

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNG
CCEEEECCCCCEEEEEEECCCCCCEEEEEEHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
LGCEIKRQSNSILQIDSTNITKTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPI
CCCEEEECCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCC
GVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGTNIFFDVVSVGATINVMLAATLAEG
CCCHHHHHHHHHHHCCCEEEEECCEEEEEECCHHCCHHHHHHHHCCCEEEEEEEEEECCC
NTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIEAGTY
CHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEECCCCCCCCEE
MIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPY
EEEEECCCCCEEECCCCHHHHHHHHHHHHHHCHHHEECCCEEEEEECCCCCCCCEECCCC
PGFPTDVQQPMSTLLTIAKGRSIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPK
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCHH
LTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHIDRGYPNIENKFRSLGATIVRL
HHHHEEEECCCCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCHHHHHHHHCHHEECC
>Mature Secondary Structure 
SKLKITGGNPLFGKVEISGAKNAAVAILPATIMASKGVCTIENTPNIEDVHCIERILNG
CEEEECCCCCEEEEEEECCCCCCEEEEEEHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
LGCEIKRQSNSILQIDSTNITKTDANTEDVRKMRASYYLIGALLGRFKKARVELPGGCPI
CCCEEEECCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCC
GVRPIDQHIKGFEALGAHVEIEHGAVIVKADKLIGTNIFFDVVSVGATINVMLAATLAEG
CCCHHHHHHHHHHHCCCEEEEECCEEEEEECCHHCCHHHHHHHHCCCEEEEEEEEEECCC
NTVLENVAKEPHVVDVANFLNSMGANIKGAGTDIIRVTGVKELKGCTYSVIPDQIEAGTY
CHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCEEEEECCHHHCCCEEEECCCCCCCCEE
MIATAACGGEVTINNVIPKHLESITAKLIEMGVDVIENGDSVTVKSKGNFKGANIKTQPY
EEEEECCCCCEEECCCCHHHHHHHHHHHHHHCHHHEECCCEEEEEECCCCCCCCEECCCC
PGFPTDVQQPMSTLLTIAKGRSIVNESIWESRFKHVDELKKMGANIKVEGRTAIIDGVPK
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCHH
LTGAIVKATDLRAGAAMVIAGLLAEGDTEILGVEHIDRGYPNIENKFRSLGATIVRL
HHHHEEEECCCCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCHHHHHHHHCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA