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The map label for this gene is sorA [H]

Identifier: 226950258

GI number: 226950258

Start: 3239599

End: 3240405

Strand: Direct

Name: sorA [H]

Synonym: CLM_3215

Alternate gene names: 226950258

Gene position: 3239599-3240405 (Clockwise)

Preceding gene: 226950252

Following gene: 226950259

Centisome position: 77.96

GC content: 39.03

Gene sequence:

>807_bases
ATGACTTTAAATATACTTCAAATTATATTAGTCATTATTGTAGCATTTCTAGCTGGTGTAGAAGGTATCTTGGATGAATT
CCAATTCCATCAACCAATAGTTGCTTGTACGTTAATCGGATTAGTTACAGGCAATTTAGTACCGTGCCTAATCTTAGGTC
GTACTCTCCAAATGATGGCCTCAGGTTGGGCAAATATCGGTGCTGCAGTAGCGCCTGATGCAGCGTTAGCATCTGTTGCA
TCTGCAATCATTCTAGTTCTTGGAGGACAAGGTAGAGAAGGAGTTCATTCAGCAATCGCTATTGCTGTTCCTCTAGCAGT
TGCAGGGTTATTATTAACAATTATTTGTCGTACAATTGCCACAGCCTTTGTACATTTTATGAATGCTGCTGCTAAAAAAG
GAAATATCAAAGCTATTGAAATGTGGCAAATCGTCGCTATTTGTTTGCAGGGTATACGTATTGCAATTCCAGCAGCCTTG
ATCTTAGCAATTGGTGATGGTCCAATTGGTGCATTACTTAATTCTATGCCTGCTTGGTTAACAGGTGGTTTAGCAGTCGG
TGGAGGAATGGTCGTAGCTGTTGGTTATGCAATGGTAATCAATATGATGGCTACAAAAGAAGTATGGCCATTTTTTGCAA
TTGGCTTTGTATTAGCAACTGTTTCAGAAATTACACTTATCGGACTTGGTGCAATAGGAGTAGCTTTAGCTCTTGTTTAC
TTAGCACTTTGTAAACAAGGTGGCTTAGGTAATGGTGAAAGCTCAAATACTGGTGATCCTTTAGGGGATATTATTGATAG
ATATTAA

Upstream 100 bases:

>100_bases
TTCAAAAGGAAATATGGATGAAATACTTAAAAAAGCACAAGGGGAATTAAATAAACAAAAATAATCTAATTATTTAAATA
AAAAAGGAGGATTAATAATC

Downstream 100 bases:

>100_bases
GAAGGGAGAGGACATGAAAATGGCAAAAGAATTAAAATTAACAAAAAAAGATCGTATTTCTGTTTGGTTGCGTTCATTTT
TCCTTCAAGGTTCTTGGAAC

Product: PTS system sorbose-specific transporter subunit IIc

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTLNILQIILVIIVAFLAGVEGILDEFQFHQPIVACTLIGLVTGNLVPCLILGRTLQMMASGWANIGAAVAPDAALASVA
SAIILVLGGQGREGVHSAIAIAVPLAVAGLLLTIICRTIATAFVHFMNAAAKKGNIKAIEMWQIVAICLQGIRIAIPAAL
ILAIGDGPIGALLNSMPAWLTGGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATVSEITLIGLGAIGVALALVY
LALCKQGGLGNGESSNTGDPLGDIIDRY

Sequences:

>Translated_268_residues
MTLNILQIILVIIVAFLAGVEGILDEFQFHQPIVACTLIGLVTGNLVPCLILGRTLQMMASGWANIGAAVAPDAALASVA
SAIILVLGGQGREGVHSAIAIAVPLAVAGLLLTIICRTIATAFVHFMNAAAKKGNIKAIEMWQIVAICLQGIRIAIPAAL
ILAIGDGPIGALLNSMPAWLTGGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATVSEITLIGLGAIGVALALVY
LALCKQGGLGNGESSNTGDPLGDIIDRY
>Mature_267_residues
TLNILQIILVIIVAFLAGVEGILDEFQFHQPIVACTLIGLVTGNLVPCLILGRTLQMMASGWANIGAAVAPDAALASVAS
AIILVLGGQGREGVHSAIAIAVPLAVAGLLLTIICRTIATAFVHFMNAAAKKGNIKAIEMWQIVAICLQGIRIAIPAALI
LAIGDGPIGALLNSMPAWLTGGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATVSEITLIGLGAIGVALALVYL
ALCKQGGLGNGESSNTGDPLGDIIDRY

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=247, Percent_Identity=48.582995951417, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1789528, Length=226, Percent_Identity=25.2212389380531, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 27392; Mature: 27261

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNILQIILVIIVAFLAGVEGILDEFQFHQPIVACTLIGLVTGNLVPCLILGRTLQMMA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGWANIGAAVAPDAALASVASAIILVLGGQGREGVHSAIAIAVPLAVAGLLLTIICRTIA
HHHHHCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFVHFMNAAAKKGNIKAIEMWQIVAICLQGIRIAIPAALILAIGDGPIGALLNSMPAWL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHH
TGGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATVSEITLIGLGAIGVALALVY
HCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALCKQGGLGNGESSNTGDPLGDIIDRY
HHHHHCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
TLNILQIILVIIVAFLAGVEGILDEFQFHQPIVACTLIGLVTGNLVPCLILGRTLQMMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGWANIGAAVAPDAALASVASAIILVLGGQGREGVHSAIAIAVPLAVAGLLLTIICRTIA
HHHHHCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFVHFMNAAAKKGNIKAIEMWQIVAICLQGIRIAIPAALILAIGDGPIGALLNSMPAWL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHH
TGGLAVGGGMVVAVGYAMVINMMATKEVWPFFAIGFVLATVSEITLIGLGAIGVALALVY
HCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALCKQGGLGNGESSNTGDPLGDIIDRY
HHHHHCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]