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The map label for this gene is fur [H]

Identifier: 226950252

GI number: 226950252

Start: 3231137

End: 3231619

Strand: Direct

Name: fur [H]

Synonym: CLM_3207

Alternate gene names: 226950252

Gene position: 3231137-3231619 (Clockwise)

Preceding gene: 226950248

Following gene: 226950258

Centisome position: 77.76

GC content: 21.95

Gene sequence:

>483_bases
ATGTCAAAGGAATTAGAATTTTATAAACATATTTTTCACTCTAATAATATCAAACTTACAACTAAACGAATTATGATTTT
AAAAATTTTCTTTGATAATAAAAATGATCATTTAACAGCAAATGAAATTTACTATTTAGTAAAAAAAATTTGTCCGTCAA
TTGGCTTAGCTACTGTTTATAGAACCATTCAAACATTATTAAAACTAGATTTGTTAGAACATTTATTATTGGAAGGTAGA
GTTAATTGTTATAAACTATTTTTTAATGAAGATACAAATTTTGAAGTTCATAATAAACATCATCCTCATCTTATTTGCCT
TGGTTGTAAAAAAATTATAGATTGTCGATATGACTTTAGTCAATATAACTTTATTAATACTGTTAAAAATCAAATAAATA
AAGACTTTTTGTTCAAAATTACTGATTTCGAAATGAATTTCTATGGATATTGTGAGAAATGTTCTGATAAAAAAAGCAAA
TAA

Upstream 100 bases:

>100_bases
AATTATTTAATGATTTTATTTAAATAAATAGAATAATATAATGTCTTTATATCCAAATTTTATGCTTATTACTTAACACT
AAAGTTTAAGGAGAATCTAT

Downstream 100 bases:

>100_bases
TAGATTTCGTGCATATAAATATTATTTTTATTAATGCTATTTATATTAAAAGAATTTACTTAACCCATTTAAATATGTAT
ATAATAGTGTTTTAAATTTT

Product: Fur family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSKELEFYKHIFHSNNIKLTTKRIMILKIFFDNKNDHLTANEIYYLVKKICPSIGLATVYRTIQTLLKLDLLEHLLLEGR
VNCYKLFFNEDTNFEVHNKHHPHLICLGCKKIIDCRYDFSQYNFINTVKNQINKDFLFKITDFEMNFYGYCEKCSDKKSK

Sequences:

>Translated_160_residues
MSKELEFYKHIFHSNNIKLTTKRIMILKIFFDNKNDHLTANEIYYLVKKICPSIGLATVYRTIQTLLKLDLLEHLLLEGR
VNCYKLFFNEDTNFEVHNKHHPHLICLGCKKIIDCRYDFSQYNFINTVKNQINKDFLFKITDFEMNFYGYCEKCSDKKSK
>Mature_159_residues
SKELEFYKHIFHSNNIKLTTKRIMILKIFFDNKNDHLTANEIYYLVKKICPSIGLATVYRTIQTLLKLDLLEHLLLEGRV
NCYKLFFNEDTNFEVHNKHHPHLICLGCKKIIDCRYDFSQYNFINTVKNQINKDFLFKITDFEMNFYGYCEKCSDKKSK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=136, Percent_Identity=27.9411764705882, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19208; Mature: 19076

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKELEFYKHIFHSNNIKLTTKRIMILKIFFDNKNDHLTANEIYYLVKKICPSIGLATVY
CCCHHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCHHHHH
RTIQTLLKLDLLEHLLLEGRVNCYKLFFNEDTNFEVHNKHHPHLICLGCKKIIDCRYDFS
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCEEEEECHHHHHHCCCCCH
QYNFINTVKNQINKDFLFKITDFEMNFYGYCEKCSDKKSK
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKELEFYKHIFHSNNIKLTTKRIMILKIFFDNKNDHLTANEIYYLVKKICPSIGLATVY
CCHHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCHHHHH
RTIQTLLKLDLLEHLLLEGRVNCYKLFFNEDTNFEVHNKHHPHLICLGCKKIIDCRYDFS
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCEEEEECHHHHHHCCCCCH
QYNFINTVKNQINKDFLFKITDFEMNFYGYCEKCSDKKSK
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]