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The map label for this gene is nagA [H]

Identifier: 226950243

GI number: 226950243

Start: 3220250

End: 3221392

Strand: Reverse

Name: nagA [H]

Synonym: CLM_3198

Alternate gene names: 226950243

Gene position: 3221392-3220250 (Counterclockwise)

Preceding gene: 226950244

Following gene: 226950242

Centisome position: 77.53

GC content: 29.48

Gene sequence:

>1143_bases
ATGAAGGCTATAGTCAACGGAAAGATTATAATAGGTAATAAAATATTAGAAAATAAAGTCTTGTTATTTGAAAAAAGGAT
AGTTGATATATTAGACAGAAAGAATATTTATTTAAGTAAAGATTACCAGATTATTGATGCTAAGGGACTATATATTTCTC
CAGGATTTATAGACGTTCATATACATGGCTCAGGTGGAAAAGATGTTATGGATGGAGAGCTAGAGTCTATAAGAGTTATA
AGCAATACTATAACTAAAAGAGGTGTAACCTCATTTTTACCAACTACTATGACTATGGCTAAAGAACATATATACAAAGC
CTTAGATGTTATAAAACAGGCTATGAATATGAATTTAGATGGTGCTAAAGTTTTAGGAGCACACTTAGAAGGTCCTTTTA
TTAATCCAAAATATAAAGGGGCTCAAAAGGAGGACTTTATAAAGAATCCAAGCTTTAATTTTATTAAAGGTTATGAGAAT
GTAATAAAAATAATTACTTTGGCTCCAGAGAAAGATGAGAATTTTGAGTTTTTAAAGGATATTAAGGAAAATACAGATAT
AGTTTTATCTATAGGCCATTCAGATGCAACCTATGAACAGGCTATGGCTGCTATAGATAATGGAATAAGTCGTGCTACGC
ATACTTTTAATGCTATGACTCCTTTAAATCATAGAAAACCGGGAATAATAGGTGCTATTATGAATACTGATATATCTTGC
GAACTTATAGCGGATAATATTCATGTTCATAAGGGAGCTATTAATATTCTTACTAAAATTAAAGGTAAAGATAAGATTAT
TTTAATTACAGATTCAATGAGAGCAGGATGTATGAACAATGGTGTATGGGAACTAGGAGGACAGAAAGTTATTGTAAAAA
ATGGTTCTGCTAGATTAGAGGATAATACTTTAGCGGGAAGTATTTTGACTTTAGATAATGCGGTTAAGAATATGAAAAAT
AATATAGAAGCTTCTTTATGTGAAGTTATATCTATGGTAACAGTTAATCCGGCCAAAGATATAAATATATATGACAGAAA
AGGAAGTATTGAAAAAGGAAAAGATGCTGATATTGTCATTTTTGATAAAGACATTAATATTAGTATGACAATTGTTGATG
GAAATATTGTTTATGAAAAATAA

Upstream 100 bases:

>100_bases
CTAATATCATAGATAATGTTAAAGATATAAGTAATAAGCTAAAAGAGAAAGTCTATTATCCTTTAAAAAGCTAATATTTT
TAGATATGGGGTGATTAAAT

Downstream 100 bases:

>100_bases
AATATTGTGACTTAGATTATTAGACACAATTAGTTATTGATTTAATAAAAGAGAAATTTAAATTTTAATGAGGTGTGTTT
TTATGAGAATTATAGTAGTG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKAIVNGKIIIGNKILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYISPGFIDVHIHGSGGKDVMDGELESIRVI
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMNLDGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFNFIKGYEN
VIKIITLAPEKDENFEFLKDIKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAINILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVYEK

Sequences:

>Translated_380_residues
MKAIVNGKIIIGNKILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYISPGFIDVHIHGSGGKDVMDGELESIRVI
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMNLDGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFNFIKGYEN
VIKIITLAPEKDENFEFLKDIKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAINILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVYEK
>Mature_380_residues
MKAIVNGKIIIGNKILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYISPGFIDVHIHGSGGKDVMDGELESIRVI
SNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMNLDGAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFNFIKGYEN
VIKIITLAPEKDENFEFLKDIKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
ELIADNIHVHKGAINILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLEDNTLAGSILTLDNAVKNMKN
NIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVIFDKDINISMTIVDGNIVYEK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=416, Percent_Identity=28.125, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI224922791, Length=416, Percent_Identity=28.3653846153846, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1786892, Length=389, Percent_Identity=32.9048843187661, Blast_Score=198, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17553768, Length=376, Percent_Identity=31.9148936170213, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI19920392, Length=395, Percent_Identity=31.3924050632911, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI281361140, Length=409, Percent_Identity=31.0513447432763, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41974; Mature: 41974

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVNGKIIIGNKILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYISPGFIDVH
CCEEECCEEEECCEECCCCHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEECCCEEEEE
IHGSGGKDVMDGELESIRVISNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMNLD
EECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFNFIKGYENVIKIITLAPEKDENFEFLKD
CHHEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHCHHCEEEEEEECCCCCCCHHHHHH
IKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
HHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCEEEEEECCCCEE
ELIADNIHVHKGAINILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLE
EEEECCEEEECCCEEEEEEECCCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCEEC
DNTLAGSILTLDNAVKNMKNNIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEE
FDKDINISMTIVDGNIVYEK
EECCCEEEEEEEECEEEEEC
>Mature Secondary Structure
MKAIVNGKIIIGNKILENKVLLFEKRIVDILDRKNIYLSKDYQIIDAKGLYISPGFIDVH
CCEEECCEEEECCEECCCCHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEECCCEEEEE
IHGSGGKDVMDGELESIRVISNTITKRGVTSFLPTTMTMAKEHIYKALDVIKQAMNMNLD
EECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAKVLGAHLEGPFINPKYKGAQKEDFIKNPSFNFIKGYENVIKIITLAPEKDENFEFLKD
CHHEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHCHHCEEEEEEECCCCCCCHHHHHH
IKENTDIVLSIGHSDATYEQAMAAIDNGISRATHTFNAMTPLNHRKPGIIGAIMNTDISC
HHCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHEEECCCCCCCCCCCEEEEEECCCCEE
ELIADNIHVHKGAINILTKIKGKDKIILITDSMRAGCMNNGVWELGGQKVIVKNGSARLE
EEEECCEEEECCCEEEEEEECCCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCEEC
DNTLAGSILTLDNAVKNMKNNIEASLCEVISMVTVNPAKDINIYDRKGSIEKGKDADIVI
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEE
FDKDINISMTIVDGNIVYEK
EECCCEEEEEEEECEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]