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The map label for this gene is ycxD [H]

Identifier: 226949310

GI number: 226949310

Start: 2298039

End: 2299385

Strand: Reverse

Name: ycxD [H]

Synonym: CLM_2230

Alternate gene names: 226949310

Gene position: 2299385-2298039 (Counterclockwise)

Preceding gene: 226949312

Following gene: 226949307

Centisome position: 55.34

GC content: 28.51

Gene sequence:

>1347_bases
ATGTATAAATATTTAAAAATATTAAATCATGTTGAGAGCTTAATTCAAGAGGGGGAGTATAAGGATGGGGATAAGTTACC
CTCTATTCGTGATTTTACTAAGATATATTCCTGCAATAAAAGTACTATTATAAAAGCTTTAGAGGCCTTAGAGAGACAGC
ATAGGATATATTCTATACCTAAGAGTGGTTATTATGTTGTAAAGAGAAAAAATCCTACCAATAGTAATAAAGAAGTATTA
TTAGATTTTGCATCCTCTGCTCCAGATCCACAGGTTTTTCCCTATCTAGATTTTCAACATTGTATTAATGAAGCCATTGA
TATATATAAGAATGAATTATTTATTTATGGGACACCTAAAGGATTACCTTCTTTAATTGATGTAATACAAAAACATTTAG
CCGATTATCAGGTTTTTGCTAATAGAGATAATATTTTTATTACCTCTGGAGTTCAGCAAGCTTTAGCTATACTAACTACA
CTAACTTTTCCAAATAAAAAGGAAACTATTTTAATAGAACAACCTAGTTATCATTTATTTATAGATTATTTAGAAACTCA
TAATGTTCCTGTATTAGGCATTAAAAGGACGGATAAAGGTATTGATTTAAATGAACTTGAGAGATTATTTAAAAGGGAAA
GTATTAAGTTCTTCTATACTATGCCTAGGTTTCATAATCCTTTAGGGTATTCTTATTCTCAAAGAGAAAGGAAAGCTATT
GTAAAACTAGCTGAAAAATATGATGTATTTATTGTGGAAGATGACTATTTAGCAGATTTAGAAGAGGATCCAAAGGCTGA
TCCCTTATATGCTTATGGTGATTTTTCGCATGTTATTTACTTGAAGAGTTATTCAAAAATTATATTCCCTGGACTTAGAA
TAGGAGTTGCGGTTATTCCTAATACCATTTTAGAGAGCTTTGGAAAATATAAAAGACTTATAGATGTAGATAGTTCCATG
CTCTCTCAAGGAGCTTTAGAAATTTATATTAAAAGTGGTATGTTTCAGAGACACAAACAAAAGATTAAGACTTCTTATTC
TTTAAGAAGTAAATGCTTAGATTCAATTCTACAAAAACAATATAAAATCTATAGTGATGTTTTTCAGTATAACCCTATTA
AAAATCCATGTATTCATACATACATAACCTTTAATGACAAAATAAATAGAGAAAGACTTATAGATAGATTGAAAAAGAAA
TCTATTATTATAGCTACAGAGAGAGGACATTATTTAAGCACATTTCCAAGGGAAAAGATTCTTAAATTAAATGTAACAAA
CATAAGAGAGGATTATATTGAGGAAGGACTTTTGGATATAATTCAAGAGATTATAAAAATGTCTTAA

Upstream 100 bases:

>100_bases
ACTCTAGAGTATAATTATATGTTAGTAGATTACTAGTTGTGGTACAATAAGAATAAAAGCTATCTATACCGGCACAGATT
TTATATAGAGGTGAAAATGT

Downstream 100 bases:

>100_bases
ATACTCTTATAGAATTAAGTCCATAAGTTATAGGATCTATATTTTATATTTAAATAATAGGAACTGCTAAAGCAGTTCCT
ATTATTTATATGTTCTATAT

Product: GntR family transcriptional regulator/class I/II aminotransferase

Products: NA

Alternate protein names: ORF8 [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MYKYLKILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIPKSGYYVVKRKNPTNSNKEVL
LDFASSAPDPQVFPYLDFQHCINEAIDIYKNELFIYGTPKGLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTT
LTFPNKKETILIEQPSYHLFIDYLETHNVPVLGIKRTDKGIDLNELERLFKRESIKFFYTMPRFHNPLGYSYSQRERKAI
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIPNTILESFGKYKRLIDVDSSM
LSQGALEIYIKSGMFQRHKQKIKTSYSLRSKCLDSILQKQYKIYSDVFQYNPIKNPCIHTYITFNDKINRERLIDRLKKK
SIIIATERGHYLSTFPREKILKLNVTNIREDYIEEGLLDIIQEIIKMS

Sequences:

>Translated_448_residues
MYKYLKILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIPKSGYYVVKRKNPTNSNKEVL
LDFASSAPDPQVFPYLDFQHCINEAIDIYKNELFIYGTPKGLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTT
LTFPNKKETILIEQPSYHLFIDYLETHNVPVLGIKRTDKGIDLNELERLFKRESIKFFYTMPRFHNPLGYSYSQRERKAI
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIPNTILESFGKYKRLIDVDSSM
LSQGALEIYIKSGMFQRHKQKIKTSYSLRSKCLDSILQKQYKIYSDVFQYNPIKNPCIHTYITFNDKINRERLIDRLKKK
SIIIATERGHYLSTFPREKILKLNVTNIREDYIEEGLLDIIQEIIKMS
>Mature_448_residues
MYKYLKILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIPKSGYYVVKRKNPTNSNKEVL
LDFASSAPDPQVFPYLDFQHCINEAIDIYKNELFIYGTPKGLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTT
LTFPNKKETILIEQPSYHLFIDYLETHNVPVLGIKRTDKGIDLNELERLFKRESIKFFYTMPRFHNPLGYSYSQRERKAI
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIPNTILESFGKYKRLIDVDSSM
LSQGALEIYIKSGMFQRHKQKIKTSYSLRSKCLDSILQKQYKIYSDVFQYNPIKNPCIHTYITFNDKINRERLIDRLKKK
SIIIATERGHYLSTFPREKILKLNVTNIREDYIEEGLLDIIQEIIKMS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=251, Percent_Identity=25.4980079681275, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI33469970, Length=251, Percent_Identity=25.4980079681275, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1787710, Length=389, Percent_Identity=26.2210796915167, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790797, Length=374, Percent_Identity=24.0641711229947, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321236, Length=342, Percent_Identity=24.8538011695906, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356535, Length=245, Percent_Identity=27.3469387755102, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52322; Mature: 52322

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50949 HTH_GNTR ; PS00050 RIBOSOMAL_L23

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKYLKILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIP
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECC
KSGYYVVKRKNPTNSNKEVLLDFASSAPDPQVFPYLDFQHCINEAIDIYKNELFIYGTPK
CCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCC
GLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTTLTFPNKKETILIEQPSYHLF
CCHHHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCEEE
IDYLETHNVPVLGIKRTDKGIDLNELERLFKRESIKFFYTMPRFHNPLGYSYSQRERKAI
EEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHH
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIP
HHHHHHCCEEEECCCHHHCCCCCCCCCCEEEECCCCEEEEEECCCHHHCCCHHHHHHHHH
NTILESFGKYKRLIDVDSSMLSQGALEIYIKSGMFQRHKQKIKTSYSLRSKCLDSILQKQ
HHHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKIYSDVFQYNPIKNPCIHTYITFNDKINRERLIDRLKKKSIIIATERGHYLSTFPREKI
HHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCEEEEEECCCCCCCCCCCHHE
LKLNVTNIREDYIEEGLLDIIQEIIKMS
EEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYKYLKILNHVESLIQEGEYKDGDKLPSIRDFTKIYSCNKSTIIKALEALERQHRIYSIP
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECC
KSGYYVVKRKNPTNSNKEVLLDFASSAPDPQVFPYLDFQHCINEAIDIYKNELFIYGTPK
CCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCC
GLPSLIDVIQKHLADYQVFANRDNIFITSGVQQALAILTTLTFPNKKETILIEQPSYHLF
CCHHHHHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCEEE
IDYLETHNVPVLGIKRTDKGIDLNELERLFKRESIKFFYTMPRFHNPLGYSYSQRERKAI
EEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHH
VKLAEKYDVFIVEDDYLADLEEDPKADPLYAYGDFSHVIYLKSYSKIIFPGLRIGVAVIP
HHHHHHCCEEEECCCHHHCCCCCCCCCCEEEECCCCEEEEEECCCHHHCCCHHHHHHHHH
NTILESFGKYKRLIDVDSSMLSQGALEIYIKSGMFQRHKQKIKTSYSLRSKCLDSILQKQ
HHHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKIYSDVFQYNPIKNPCIHTYITFNDKINRERLIDRLKKKSIIIATERGHYLSTFPREKI
HHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCEEEEEECCCCCCCCCCCHHE
LKLNVTNIREDYIEEGLLDIIQEIIKMS
EEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8355609; 8969502; 9384377 [H]