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The map label for this gene is aspB [H]

Identifier: 226949312

GI number: 226949312

Start: 2300741

End: 2301892

Strand: Reverse

Name: aspB [H]

Synonym: CLM_2232

Alternate gene names: 226949312

Gene position: 2301892-2300741 (Counterclockwise)

Preceding gene: 226949313

Following gene: 226949310

Centisome position: 55.4

GC content: 28.99

Gene sequence:

>1152_bases
ATGAAAAATAAATTTTTAGCCCATAAGTATAAAGAAAATGAAAATAATTTAATGTCGGAAACCGCTAATTTAAAAAAGAA
GTTTAAAGATATAATTGATTTAAGCTTAGGAGATCCAGATATAATAACAGATAAATCTATTATACAGACTGCTTTTAAGG
ATACAAAAAAGGGATATACCAGATATTCAGATCCGACAGGAGATAAAGAATTAATAGAGGGTATTATTAATTTTTATAAA
AAAGATCGCAATATAAGTTTTAAAAAAAATGAAATTATGGCAGTAGTGGGAGCTTGTCATGGTATGTATTTAGCTCTGCA
ATCCATTATAAATCCTGGTGAGGAAGTAATAGTACATTCTCCTTATTTTACTCCATACAAAGAACAAATAGAGATGGTAG
GCGGAAAATTTATTGAATTTGAAACCTTAGAAGAAGATGAGTTTAATATAAACCCTAAAAAATTAGAAAAATTAATAAAC
AGTAAAACAAAAGCTATAGTATTAAATTCTCCTAATAATCCTACAGGTGCATTTTTTTCTAAGGAATTGTTAAAAGAAAT
AACTAAAATAGCTATAGAAAATGATTTAGTTATAATATCTGATGAGGTTTATGATGGGTTCACCTATTACGAGGATTTTT
GCTCTATAGCTTCCTTAGAAGGGATGAAAGAGAGAACCATAACTTTAGGTAGTTTTTCAAAGGATTTTTGTATGACTGGG
TGGAGAATTGGTTATGTAGCTGCTCCAGATTATATAATTAACACTATGAAAAATATTAATGAAGGTATATGTTTTTCTGC
TCCTACAATTTCTCAAAGAGCTGCTATATATGCTTTGAAAAATAGAGATAACATTGTAGATAAAATAAAGAAGGAATTTA
GAGAAAGAATGGAATATGCCTATAGTAGAATAGAGTCTATGCCTAAATTAAATGCTTTTAAACCTAAAGCAGGCATATAT
ATATTTGCGAATATAAAGGAAACAGGCAAGAGTTCTGAAGAGTTTTGTGATGAATTATTAAACAAAGCTCATATAGTAGC
AATACCGGGAAAGGCCTTTGGTAAGTATGGAGAAGGATACATAAGAATTGCTTGTACAGTAGGGCTAGAGGAATTAGAGC
AAGCTTTTAATAGAATTGAAAAAATACTATAA

Upstream 100 bases:

>100_bases
CTAGAAGAGGGAACACCGGAGGATATATTTAACAATGCTAAAAATTCAAGGACAAAGGACTTTCTAAGTAAAATAATTTA
GTTTAGAGAAGGAGTATGTT

Downstream 100 bases:

>100_bases
ACAGATTCCTAAGCTTCAGGGGGAGTATTTACTCCTACTAAAGCTTAGGAAATGGTTATCCGATGACTACCAGCTCTTTA
CTCCCACTTTGAAGAAGATG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYTRYSDPTGDKELIEGIINFYK
KDRNISFKKNEIMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFSKELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIESMPKLNAFKPKAGIY
IFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELEQAFNRIEKIL

Sequences:

>Translated_383_residues
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYTRYSDPTGDKELIEGIINFYK
KDRNISFKKNEIMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFSKELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIESMPKLNAFKPKAGIY
IFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELEQAFNRIEKIL
>Mature_383_residues
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYTRYSDPTGDKELIEGIINFYK
KDRNISFKKNEIMAVVGACHGMYLALQSIINPGEEVIVHSPYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLIN
SKTKAIVLNSPNNPTGAFFSKELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYAYSRIESMPKLNAFKPKAGIY
IFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGYIRIACTVGLEELEQAFNRIEKIL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=388, Percent_Identity=28.6082474226804, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI169881279, Length=388, Percent_Identity=28.6082474226804, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI56713254, Length=317, Percent_Identity=29.6529968454259, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI56713256, Length=317, Percent_Identity=29.6529968454259, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI169881281, Length=297, Percent_Identity=30.6397306397306, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=25.1989389920424, Blast_Score=118, Evalue=9e-27,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=25.7894736842105, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786816, Length=355, Percent_Identity=22.5352112676056, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788627, Length=389, Percent_Identity=24.4215938303342, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787710, Length=329, Percent_Identity=22.7963525835866, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788332, Length=308, Percent_Identity=21.4285714285714, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790797, Length=288, Percent_Identity=26.7361111111111, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=326, Percent_Identity=30.0613496932515, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=421, Percent_Identity=25.6532066508314, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=228, Percent_Identity=32.0175438596491, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=228, Percent_Identity=32.0175438596491, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6322401, Length=370, Percent_Identity=28.6486486486486, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28573069, Length=324, Percent_Identity=25.6172839506173, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646114, Length=324, Percent_Identity=25.6172839506173, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573067, Length=324, Percent_Identity=25.6172839506173, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573065, Length=324, Percent_Identity=25.6172839506173, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859735, Length=368, Percent_Identity=23.0978260869565, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24641770, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641760, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641768, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641766, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641764, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45551451, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43645; Mature: 43645

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYT
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
RYSDPTGDKELIEGIINFYKKDRNISFKKNEIMAVVGACHGMYLALQSIINPGEEVIVHS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLINSKTKAIVLNSPNNPTGAFFS
CCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHH
KELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
HHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHCC
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYA
CEEEEEECCHHHHHHHHHCCCCCEECCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHH
YSRIESMPKLNAFKPKAGIYIFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGY
HHHHHCCCCCCCCCCCCCEEEEEECHHCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCCE
IRIACTVGLEELEQAFNRIEKIL
EEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKFLAHKYKENENNLMSETANLKKKFKDIIDLSLGDPDIITDKSIIQTAFKDTKKGYT
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
RYSDPTGDKELIEGIINFYKKDRNISFKKNEIMAVVGACHGMYLALQSIINPGEEVIVHS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PYFTPYKEQIEMVGGKFIEFETLEEDEFNINPKKLEKLINSKTKAIVLNSPNNPTGAFFS
CCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHH
KELLKEITKIAIENDLVIISDEVYDGFTYYEDFCSIASLEGMKERTITLGSFSKDFCMTG
HHHHHHHHHHHHCCCEEEEECHHHCCHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHCC
WRIGYVAAPDYIINTMKNINEGICFSAPTISQRAAIYALKNRDNIVDKIKKEFRERMEYA
CEEEEEECCHHHHHHHHHCCCCCEECCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHH
YSRIESMPKLNAFKPKAGIYIFANIKETGKSSEEFCDELLNKAHIVAIPGKAFGKYGEGY
HHHHHCCCCCCCCCCCCCEEEEEECHHCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCCE
IRIACTVGLEELEQAFNRIEKIL
EEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]