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The map label for this gene is rbsK [H]

Identifier: 226948895

GI number: 226948895

Start: 1836176

End: 1837087

Strand: Direct

Name: rbsK [H]

Synonym: CLM_1805

Alternate gene names: 226948895

Gene position: 1836176-1837087 (Clockwise)

Preceding gene: 226948894

Following gene: 226948896

Centisome position: 44.19

GC content: 29.93

Gene sequence:

>912_bases
ATGGATATTGCAGTTATTGGTTCAAATATGGTAGATTTGATAAGTTATATTGATAGAATGCCTAAAGAAGGTGAGACTTT
AGAAGCACCAGATTTTAAAATGGGATTTGGGGGTAAGGGAGCAAACCAGGCCGTTACAGCTGCAAGATTAAAATCAGATG
TTATGATGGTAAGTAAAGTTGGAGATGATTTATTTGGACAAAACACTATTAAAAATTTTAAAAACAATGGTGTAAATACA
GATTTTGTAACTGTTCAAAAAAATCAAGCTAGTGGAGTTGCACCTATTTTTGTTGATAGAGAATCTAAAAATAGTATTTT
AATTATTAAAGGTGCCAATAAAAATTTATCTCCTACAGATATAGATGATGCAAGTGAAGAATTGAAAAAGTGTTCTTTAA
TTATTTTACAATTGGAAATTGAATTAGAAACTGTTTATTATGCTATAGATTTTGCTAATAAGAATAATATTTCTGTATTG
TTAAATCCTGCGCCTGCTACAAAAGAACTTGATTTCAATTATGTTTATAAGTGCGATTTTTTTGTTCCAAATGAAACAGA
ATTAGAGATTTTAACAAATAAATCTGTAAATACAATAGGAGAGATAAAAGAAGCTGCTCATTTAATTGGGGATAAAGGTG
TTAAAAATGTAATTGTTACAATGGGCAGTAAAGGTTTACTGTGGATTAATAAAGATGAAGAACATTTTATAAAAGCACGT
AAAGTTGATGCCGTGGATACCACTGGTGCTGGTGATGGATTTATTGGATGTTTTGCACATTATTATGTAGCCACAAAAAA
CATATTATTAGCTCTTGAAAAAGCAACAGCTTATGCAGCACTTAGTGTTACAAGATATGGTACTCAAACTTCTTATCCTA
CAAAGGAGGAGTTTGAAGAATTTTTAAAATAA

Upstream 100 bases:

>100_bases
TTTAAATAGAACTCCAAGCTTTCAATATAAAGTAAGTAAATACTAAAATAAGTAGATGTAAGATGTACTACATTAAATAT
TGAAAGGAAGTGCTTAAATA

Downstream 100 bases:

>100_bases
GTTTTAGGTTTGAGAAATTTTACTGTATAAAAATATATTTTTAAAAACAAAGACTCCTATACATTAGTGTAGGGTTTTTT
GTTTTGTGGAAAATAAAAAT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDIAVIGSNMVDLISYIDRMPKEGETLEAPDFKMGFGGKGANQAVTAARLKSDVMMVSKVGDDLFGQNTIKNFKNNGVNT
DFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTDIDDASEELKKCSLIILQLEIELETVYYAIDFANKNNISVL
LNPAPATKELDFNYVYKCDFFVPNETELEILTNKSVNTIGEIKEAAHLIGDKGVKNVIVTMGSKGLLWINKDEEHFIKAR
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEEFLK

Sequences:

>Translated_303_residues
MDIAVIGSNMVDLISYIDRMPKEGETLEAPDFKMGFGGKGANQAVTAARLKSDVMMVSKVGDDLFGQNTIKNFKNNGVNT
DFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTDIDDASEELKKCSLIILQLEIELETVYYAIDFANKNNISVL
LNPAPATKELDFNYVYKCDFFVPNETELEILTNKSVNTIGEIKEAAHLIGDKGVKNVIVTMGSKGLLWINKDEEHFIKAR
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEEFLK
>Mature_303_residues
MDIAVIGSNMVDLISYIDRMPKEGETLEAPDFKMGFGGKGANQAVTAARLKSDVMMVSKVGDDLFGQNTIKNFKNNGVNT
DFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTDIDDASEELKKCSLIILQLEIELETVYYAIDFANKNNISVL
LNPAPATKELDFNYVYKCDFFVPNETELEILTNKSVNTIGEIKEAAHLIGDKGVKNVIVTMGSKGLLWINKDEEHFIKAR
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEEFLK

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=41.2162162162162, Blast_Score=222, Evalue=3e-58,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=37, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI87082343, Length=307, Percent_Identity=28.9902280130293, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788493, Length=74, Percent_Identity=37.8378378378378, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788484, Length=250, Percent_Identity=22.4, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=39.7394136807818, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6319884, Length=327, Percent_Identity=30.5810397553517, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=34.6534653465347, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=29.2763157894737, Blast_Score=127, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33337; Mature: 33337

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAVIGSNMVDLISYIDRMPKEGETLEAPDFKMGFGGKGANQAVTAARLKSDVMMVSKV
CEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHEEHHH
GDDLFGQNTIKNFKNNGVNTDFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTD
CCHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
IDDASEELKKCSLIILQLEIELETVYYAIDFANKNNISVLLNPAPATKELDFNYVYKCDF
CCHHHHHHHHEEEEEEEEEEEEEEEEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEEE
FVPNETELEILTNKSVNTIGEIKEAAHLIGDKGVKNVIVTMGSKGLLWINKDEEHFIKAR
ECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHH
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEE
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECHHEEEEEEEEECCCCCCCCCHHHHHH
FLK
HHC
>Mature Secondary Structure
MDIAVIGSNMVDLISYIDRMPKEGETLEAPDFKMGFGGKGANQAVTAARLKSDVMMVSKV
CEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHEEHHH
GDDLFGQNTIKNFKNNGVNTDFVTVQKNQASGVAPIFVDRESKNSILIIKGANKNLSPTD
CCHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
IDDASEELKKCSLIILQLEIELETVYYAIDFANKNNISVLLNPAPATKELDFNYVYKCDF
CCHHHHHHHHEEEEEEEEEEEEEEEEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEEE
FVPNETELEILTNKSVNTIGEIKEAAHLIGDKGVKNVIVTMGSKGLLWINKDEEHFIKAR
ECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHH
KVDAVDTTGAGDGFIGCFAHYYVATKNILLALEKATAYAALSVTRYGTQTSYPTKEEFEE
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECHHEEEEEEEEECCCCCCCCCHHHHHH
FLK
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]