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The map label for this gene is tagO [H]

Identifier: 226947371

GI number: 226947371

Start: 177238

End: 178272

Strand: Direct

Name: tagO [H]

Synonym: CLM_0191

Alternate gene names: 226947371

Gene position: 177238-178272 (Clockwise)

Preceding gene: 226947370

Following gene: 226947372

Centisome position: 4.27

GC content: 30.63

Gene sequence:

>1035_bases
ATGGATACAAAATTGTACATAATTGGAGCTATTACAGCTATAGTGCTATCAGTTATTTTAACACCTATAGTAAAAAAAGC
TGCATTTATATTAGGTGTAGTAGATATACCTAAGGATAAAAGAAAAATTCATAAAAAACCTATACCACTTTTAGGTGGTA
TAGCAATATACATATCTTTTGTAGTTGCTTTGATATTAAAAAAGGGGCCTCTAACTTTAGAAGAAATAGGAATAATATTA
GGATCTACAGTTATAGTTATAGGCGGATTTATTGATGATAAGTATGATATGTCTCCTATAAAAAAAATTCTATTTCAATT
AGCTGCAGCTATTTGTTTAATAATATGTGGATTAAAAATACAATTCATAACGAATCCTTTTGATCACCTTAACTTATATG
TAGGATTACATATTTTTGCTATACCTATAACTATAGTATGGGTTATAGGTATAACTAATGCATTAAATTTAATAGATGGG
CTTGATGGATTAGCGGCAGGGGTTGCACTAATTTCATGTATTACAATGTTTGTAATAGCTGTTCTAAATCAAAGATGGGA
AGCAGCTATATTAACTAGTATATTAGGTGGGTCTATATTAGGATTTTTGCCCTATAACTTTAATCCAGCATCCATATTTA
TGGGGGATACTGGATCTCAACTTTTAGGATTTTTGTTGGCGGCTATATCAATAGAGGGAGCTATTAAATCTGCTACAGCT
TTTGCTATAGTCGTACCAATATTAGCGTTAGGATTACCTATATATGACACATTGTTTGCCATGATTAGAAGAAAAATAAA
CGGGAAGCCAATAATGCAAGCAGATAGGGGGCATCTTCATCATAGACTTTTAGATATGGGATTAACTCAACGTCAAGCGG
TTATAATAATGTATTTAATAAGTGCTGTATTAGGAAGCTTTGCTATAATAGCTATGCAAATAAGTAATCAAAAGTCATAT
TTTTTACTTACAGCAATAATGCTAGCTCTTATATTAATAGCATGGAAATGTGGATTTTTTAGCCATAAAGAATAA

Upstream 100 bases:

>100_bases
ATAAATTGATTTATAGCTCTTTTGTTTATCATAGCTGGCTTGGCATGGTTAATATTGATTAAATAATAAGTCCTGTAATT
AGATTAAGGAGAGTTTTATA

Downstream 100 bases:

>100_bases
GGAGGCAAGAAAAGTGGATAAGATAAAAACCATTACTATATTTGGAACTAGACCAGAAGCTATAAAAATGGCACCTTTAG
TTAAAGAATTGGAAAAAAGA

Product: undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MDTKLYIIGAITAIVLSVILTPIVKKAAFILGVVDIPKDKRKIHKKPIPLLGGIAIYISFVVALILKKGPLTLEEIGIIL
GSTVIVIGGFIDDKYDMSPIKKILFQLAAAICLIICGLKIQFITNPFDHLNLYVGLHIFAIPITIVWVIGITNALNLIDG
LDGLAAGVALISCITMFVIAVLNQRWEAAILTSILGGSILGFLPYNFNPASIFMGDTGSQLLGFLLAAISIEGAIKSATA
FAIVVPILALGLPIYDTLFAMIRRKINGKPIMQADRGHLHHRLLDMGLTQRQAVIIMYLISAVLGSFAIIAMQISNQKSY
FLLTAIMLALILIAWKCGFFSHKE

Sequences:

>Translated_344_residues
MDTKLYIIGAITAIVLSVILTPIVKKAAFILGVVDIPKDKRKIHKKPIPLLGGIAIYISFVVALILKKGPLTLEEIGIIL
GSTVIVIGGFIDDKYDMSPIKKILFQLAAAICLIICGLKIQFITNPFDHLNLYVGLHIFAIPITIVWVIGITNALNLIDG
LDGLAAGVALISCITMFVIAVLNQRWEAAILTSILGGSILGFLPYNFNPASIFMGDTGSQLLGFLLAAISIEGAIKSATA
FAIVVPILALGLPIYDTLFAMIRRKINGKPIMQADRGHLHHRLLDMGLTQRQAVIIMYLISAVLGSFAIIAMQISNQKSY
FLLTAIMLALILIAWKCGFFSHKE
>Mature_344_residues
MDTKLYIIGAITAIVLSVILTPIVKKAAFILGVVDIPKDKRKIHKKPIPLLGGIAIYISFVVALILKKGPLTLEEIGIIL
GSTVIVIGGFIDDKYDMSPIKKILFQLAAAICLIICGLKIQFITNPFDHLNLYVGLHIFAIPITIVWVIGITNALNLIDG
LDGLAAGVALISCITMFVIAVLNQRWEAAILTSILGGSILGFLPYNFNPASIFMGDTGSQLLGFLLAAISIEGAIKSATA
FAIVVPILALGLPIYDTLFAMIRRKINGKPIMQADRGHLHHRLLDMGLTQRQAVIIMYLISAVLGSFAIIAMQISNQKSY
FLLTAIMLALILIAWKCGFFSHKE

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=313, Percent_Identity=28.4345047923323, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 37260; Mature: 37260

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKLYIIGAITAIVLSVILTPIVKKAAFILGVVDIPKDKRKIHKKPIPLLGGIAIYISF
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
VVALILKKGPLTLEEIGIILGSTVIVIGGFIDDKYDMSPIKKILFQLAAAICLIICGLKI
HHHHHHCCCCCCHHHHHHHHCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHH
QFITNPFDHLNLYVGLHIFAIPITIVWVIGITNALNLIDGLDGLAAGVALISCITMFVIA
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VLNQRWEAAILTSILGGSILGFLPYNFNPASIFMGDTGSQLLGFLLAAISIEGAIKSATA
HHHCCHHHHHHHHHHHCHHHEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
FAIVVPILALGLPIYDTLFAMIRRKINGKPIMQADRGHLHHRLLDMGLTQRQAVIIMYLI
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
SAVLGSFAIIAMQISNQKSYFLLTAIMLALILIAWKCGFFSHKE
HHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDTKLYIIGAITAIVLSVILTPIVKKAAFILGVVDIPKDKRKIHKKPIPLLGGIAIYISF
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
VVALILKKGPLTLEEIGIILGSTVIVIGGFIDDKYDMSPIKKILFQLAAAICLIICGLKI
HHHHHHCCCCCCHHHHHHHHCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHH
QFITNPFDHLNLYVGLHIFAIPITIVWVIGITNALNLIDGLDGLAAGVALISCITMFVIA
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VLNQRWEAAILTSILGGSILGFLPYNFNPASIFMGDTGSQLLGFLLAAISIEGAIKSATA
HHHCCHHHHHHHHHHHCHHHEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
FAIVVPILALGLPIYDTLFAMIRRKINGKPIMQADRGHLHHRLLDMGLTQRQAVIIMYLI
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
SAVLGSFAIIAMQISNQKSYFLLTAIMLALILIAWKCGFFSHKE
HHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]