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The map label for this gene is mnaA [C]

Identifier: 226947372

GI number: 226947372

Start: 178286

End: 179443

Strand: Direct

Name: mnaA [C]

Synonym: CLM_0192

Alternate gene names: 226947372

Gene position: 178286-179443 (Clockwise)

Preceding gene: 226947371

Following gene: 226947373

Centisome position: 4.29

GC content: 29.27

Gene sequence:

>1158_bases
GTGGATAAGATAAAAACCATTACTATATTTGGAACTAGACCAGAAGCTATAAAAATGGCACCTTTAGTTAAAGAATTGGA
AAAAAGAGAAGAAATAGAAAATAGAGTGTGTGTGACAGCACAACATAGAGAAATGTTAGATCAAGTTTTAGAATTATTTA
ATATAAAACCAGATTTTGATCTTAATATAATGAAATCAAAACAAAGTCTTACAGGCATAACTACCAGAGTATTAGAAGGA
TTAGAAGAAATCTTTGATAAAGAAAAACCTAATTTAATATTAGTTCATGGTGATACAACTACAACTTTTGCAGGAGCTTT
AGCAGGTTTTTATAAGCAAATAAAAGTGGGGCATGTAGAAGCTGGATTAAGAACTTTTGATAAGTATTTTCCTTTCCCAG
AGGAAATGAACAGAAAACTTACAGGAAGTATAGCAGATTTAAATTTTGCTCCTACTGTGGGATCTAAGAATAATTTACTA
AGAGAGGCTATAGATGAAGAAAGTATATTTGTAACAGGAAATACAGTCATAGATGCTATGGAGTTTACTGTAGAACAAGA
CTATATTTTCGAAAATAAAGATTTAAATATGATAGATTATGAAAATAAAAAGGTAATAATGGTTACTGCTCATAGAAGAG
AAAATTGGGGTGAAGGTATAGAAAATATTTGTAATGCACTAAAAACTATAGTAGAAAAATACAAGGATGTGGAGATTGTA
TATTTAGTTCATTTAAACCCAGTGGTAAGAGATACAGTTTATAGTATATTAGGAGATTTAGAAAGAGTACATTTATTAAA
TCCATTAGATACAAAAGAAACACATAATTTAATGAATAAATGTTATATGTTAATGACAGATTCAGGTGGACTCCAAGAAG
AAGCACCTCATTTAGGTAAACCTGTTTTAGTATTAAGAGATGTAACAGAAAGACCAGAAGCTGTAAAAGTAGGAACAGTT
AGGCTTGTGGGTACAGATAAGGAAGTTATAACTAAAGAGGTATTCGATTTAATAGAAAACAAACAAAAGTATGATATTAT
GAGCAAAGCTATAAATCCATATGGGGATGGTAAAGCGTCAATTAGAATAGTGGATAGTATATTATATTATTTTGATAAGA
TAGAAAAAAGACCACAAGAATTTCATGCTAATAAATAA

Upstream 100 bases:

>100_bases
CAAAAGTCATATTTTTTACTTACAGCAATAATGCTAGCTCTTATATTAATAGCATGGAAATGTGGATTTTTTAGCCATAA
AGAATAAGGAGGCAAGAAAA

Downstream 100 bases:

>100_bases
TAAAATAAAATATGGATAAAATAAAGAGAAGTAACATAATTATATTATTTTTATGTTACTCTTTTTATAAAAATTATTGA
AAGAATATAAATCTATTAAT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDKIKTITIFGTRPEAIKMAPLVKELEKREEIENRVCVTAQHREMLDQVLELFNIKPDFDLNIMKSKQSLTGITTRVLEG
LEEIFDKEKPNLILVHGDTTTTFAGALAGFYKQIKVGHVEAGLRTFDKYFPFPEEMNRKLTGSIADLNFAPTVGSKNNLL
REAIDEESIFVTGNTVIDAMEFTVEQDYIFENKDLNMIDYENKKVIMVTAHRRENWGEGIENICNALKTIVEKYKDVEIV
YLVHLNPVVRDTVYSILGDLERVHLLNPLDTKETHNLMNKCYMLMTDSGGLQEEAPHLGKPVLVLRDVTERPEAVKVGTV
RLVGTDKEVITKEVFDLIENKQKYDIMSKAINPYGDGKASIRIVDSILYYFDKIEKRPQEFHANK

Sequences:

>Translated_385_residues
MDKIKTITIFGTRPEAIKMAPLVKELEKREEIENRVCVTAQHREMLDQVLELFNIKPDFDLNIMKSKQSLTGITTRVLEG
LEEIFDKEKPNLILVHGDTTTTFAGALAGFYKQIKVGHVEAGLRTFDKYFPFPEEMNRKLTGSIADLNFAPTVGSKNNLL
REAIDEESIFVTGNTVIDAMEFTVEQDYIFENKDLNMIDYENKKVIMVTAHRRENWGEGIENICNALKTIVEKYKDVEIV
YLVHLNPVVRDTVYSILGDLERVHLLNPLDTKETHNLMNKCYMLMTDSGGLQEEAPHLGKPVLVLRDVTERPEAVKVGTV
RLVGTDKEVITKEVFDLIENKQKYDIMSKAINPYGDGKASIRIVDSILYYFDKIEKRPQEFHANK
>Mature_385_residues
MDKIKTITIFGTRPEAIKMAPLVKELEKREEIENRVCVTAQHREMLDQVLELFNIKPDFDLNIMKSKQSLTGITTRVLEG
LEEIFDKEKPNLILVHGDTTTTFAGALAGFYKQIKVGHVEAGLRTFDKYFPFPEEMNRKLTGSIADLNFAPTVGSKNNLL
REAIDEESIFVTGNTVIDAMEFTVEQDYIFENKDLNMIDYENKKVIMVTAHRRENWGEGIENICNALKTIVEKYKDVEIV
YLVHLNPVVRDTVYSILGDLERVHLLNPLDTKETHNLMNKCYMLMTDSGGLQEEAPHLGKPVLVLRDVTERPEAVKVGTV
RLVGTDKEVITKEVFDLIENKQKYDIMSKAINPYGDGKASIRIVDSILYYFDKIEKRPQEFHANK

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=55.9139784946236, Blast_Score=396, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 44046; Mature: 44046

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIKTITIFGTRPEAIKMAPLVKELEKREEIENRVCVTAQHREMLDQVLELFNIKPDFD
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCC
LNIMKSKQSLTGITTRVLEGLEEIFDKEKPNLILVHGDTTTTFAGALAGFYKQIKVGHVE
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
AGLRTFDKYFPFPEEMNRKLTGSIADLNFAPTVGSKNNLLREAIDEESIFVTGNTVIDAM
HHHHHHHHHCCCHHHHCHHHCCCEECCCCCCCCCCCHHHHHHHCCCCCEEEECCHHHHHH
EFTVEQDYIFENKDLNMIDYENKKVIMVTAHRRENWGEGIENICNALKTIVEKYKDVEIV
HHHCCCCEEEECCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
YLVHLNPVVRDTVYSILGDLERVHLLNPLDTKETHNLMNKCYMLMTDSGGLQEEAPHLGK
EEEECCHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCCC
PVLVLRDVTERPEAVKVGTVRLVGTDKEVITKEVFDLIENKQKYDIMSKAINPYGDGKAS
CEEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
IRIVDSILYYFDKIEKRPQEFHANK
HHHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure
MDKIKTITIFGTRPEAIKMAPLVKELEKREEIENRVCVTAQHREMLDQVLELFNIKPDFD
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCC
LNIMKSKQSLTGITTRVLEGLEEIFDKEKPNLILVHGDTTTTFAGALAGFYKQIKVGHVE
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
AGLRTFDKYFPFPEEMNRKLTGSIADLNFAPTVGSKNNLLREAIDEESIFVTGNTVIDAM
HHHHHHHHHCCCHHHHCHHHCCCEECCCCCCCCCCCHHHHHHHCCCCCEEEECCHHHHHH
EFTVEQDYIFENKDLNMIDYENKKVIMVTAHRRENWGEGIENICNALKTIVEKYKDVEIV
HHHCCCCEEEECCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
YLVHLNPVVRDTVYSILGDLERVHLLNPLDTKETHNLMNKCYMLMTDSGGLQEEAPHLGK
EEEECCHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCCC
PVLVLRDVTERPEAVKVGTVRLVGTDKEVITKEVFDLIENKQKYDIMSKAINPYGDGKAS
CEEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHH
IRIVDSILYYFDKIEKRPQEFHANK
HHHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286; 7867955 [H]