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The map label for this gene is licA [H]

Identifier: 226225317

GI number: 226225317

Start: 2819017

End: 2819325

Strand: Direct

Name: licA [H]

Synonym: Lm4b_02740

Alternate gene names: 226225317

Gene position: 2819017-2819325 (Clockwise)

Preceding gene: 226225316

Following gene: 226225322

Centisome position: 96.78

GC content: 40.13

Gene sequence:

>309_bases
ATGAATGAAATGGAAACAGTAATTTTTGGCATGATTAGCCAAGTTGGTTCTGCCAGAAGCAGTTACTTAGAAGGGCTTCG
TGCGGCTCGTGAAGGCAATTTCGAGGAAGCAGAAGCAAAACTACAAGAAGGTAGCGAAACTCTTGCAAATGGGCACCACG
AGCATCATAAGCTAATCCAAAAAGAAGCTTCCGGTGAAAAAGTGGAAATCCAATTACTTTTAATCCATGCGGAAGACTTA
CTCATCACAACCGAAACTTTAAGAGAAGTTGTCACTGAGTTCGTGCATGTATATAAAAAAATAAGCTAA

Upstream 100 bases:

>100_bases
AGCTTTGGGCTGCGTGACACAATTATCGAAACAGCAACACATAAAAACCAAGCTGGCCTACTCGGCGCAGTGTATCACTT
TTTACAGGAGGAAAATAGAC

Downstream 100 bases:

>100_bases
AAAAAGCGTGTAGGCACTGAAACCTACACGCTTTTCTATTCGTCTATTTGCTCTTGATTATAATTTTTCTTCGCCATCGC
TTCCAGTAAAAAAAGTACCG

Product: PTS cellobiose-specific enzyme IIA

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MNEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQKEASGEKVEIQLLLIHAEDL
LITTETLREVVTEFVHVYKKIS

Sequences:

>Translated_102_residues
MNEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQKEASGEKVEIQLLLIHAEDL
LITTETLREVVTEFVHVYKKIS
>Mature_102_residues
MNEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQKEASGEKVEIQLLLIHAEDL
LITTETLREVVTEFVHVYKKIS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=99, Percent_Identity=34.3434343434343, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 11476; Mature: 11476

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHH
KEASGEKVEIQLLLIHAEDLLITTETLREVVTEFVHVYKKIS
HHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHH
KEASGEKVEIQLLLIHAEDLLITTETLREVVTEFVHVYKKIS
HHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]