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The map label for this gene is bglK [H]

Identifier: 226225316

GI number: 226225316

Start: 2818140

End: 2819024

Strand: Direct

Name: bglK [H]

Synonym: Lm4b_02739

Alternate gene names: 226225316

Gene position: 2818140-2819024 (Clockwise)

Preceding gene: 226225315

Following gene: 226225317

Centisome position: 96.75

GC content: 43.95

Gene sequence:

>885_bases
ATGAAAATTGCAGCTTTTGATATCGGTGGAACGGCCCTTAAAATGGGGGTCGTTTTGCCGCATGGTGAAATTATACTAAC
AAAATCCGCCGAAATCAGCGGTAGTGATGGCGACCAGATTTTAGCAGAAATGAAGCTATTTCTTGCTGAAAATACGGACG
TGACAGGAATTGCAGTCAGCGCGCCTGGCTATGTGAACCCAAAAACCGGACTTATTACAATGGGCGGCGCTATCCGTAGA
TTTGATAACTTTAATTTGAAAGAATGGCTTGAAGCAGAAACCGGAATTCCTGTTGCCATTGAAAATGACGCCAATTGCGC
CCTTCTTGCCGAAAAATGGCTTGGTAAAGGACAAAATTTGGATGATTTTCTTTGTCTAACAATCGGAACTGGGATTGGCG
GCGGAATTTTTTCCAATGGCGCATTAGTTCGTGGTGGTCGTTTCCGGGCTGGCGAGTTTGGTTATATGTTTAGCGAACGT
CCAGGGGCTTTCCGTCCTGGCAAATATACGCTAAATGAGACTACGACAATGCTTGTTCTTCGCAGACAATACGCGGAACT
TACTGGGCGCCCTTTGGAAGAGATTACTGGCGAAGAAATTTTTGCTAAGTATGATGGACACGACGCCGTCTCAGAACGTC
TTATTACTGAGTTTTATACTGGAATTTGTACGGGGCTTTATAATTTAATTTACTTGTTCGATCCAACGCATATCTTTATT
GGTGGTGGAATTACAAGTCGCCCTACTTTTATCACGGAGCTAAAGCATCATGTGGAGAGCTTTGGGCTGCGTGACACAAT
TATCGAAACAGCAACACATAAAAACCAAGCTGGCCTACTCGGCGCAGTGTATCACTTTTTACAGGAGGAAAATAGACATG
AATGA

Upstream 100 bases:

>100_bases
TTTATCTACCATTCGTACTTGTATCTAACAAAATTGCCGCGAGTGATGCTGCAATGGACAAAAATGCAACAGCCTCAACA
GAACAATAGGATGTGACAAA

Downstream 100 bases:

>100_bases
AATGGAAACAGTAATTTTTGGCATGATTAGCCAAGTTGGTTCTGCCAGAAGCAGTTACTTAGAAGGGCTTCGTGCGGCTC
GTGAAGGCAATTTCGAGGAA

Product: xylose operon regulatory protein and to glucose kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEMKLFLAENTDVTGIAVSAPGYVNPKTGLITMGGAIRR
FDNFNLKEWLEAETGIPVAIENDANCALLAEKWLGKGQNLDDFLCLTIGTGIGGGIFSNGALVRGGRFRAGEFGYMFSER
PGAFRPGKYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFAKYDGHDAVSERLITEFYTGICTGLYNLIYLFDPTHIFI
GGGITSRPTFITELKHHVESFGLRDTIIETATHKNQAGLLGAVYHFLQEENRHE

Sequences:

>Translated_294_residues
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEMKLFLAENTDVTGIAVSAPGYVNPKTGLITMGGAIRR
FDNFNLKEWLEAETGIPVAIENDANCALLAEKWLGKGQNLDDFLCLTIGTGIGGGIFSNGALVRGGRFRAGEFGYMFSER
PGAFRPGKYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFAKYDGHDAVSERLITEFYTGICTGLYNLIYLFDPTHIFI
GGGITSRPTFITELKHHVESFGLRDTIIETATHKNQAGLLGAVYHFLQEENRHE
>Mature_294_residues
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEMKLFLAENTDVTGIAVSAPGYVNPKTGLITMGGAIRR
FDNFNLKEWLEAETGIPVAIENDANCALLAEKWLGKGQNLDDFLCLTIGTGIGGGIFSNGALVRGGRFRAGEFGYMFSER
PGAFRPGKYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFAKYDGHDAVSERLITEFYTGICTGLYNLIYLFDPTHIFI
GGGITSRPTFITELKHHVESFGLRDTIIETATHKNQAGLLGAVYHFLQEENRHE

Specific function: Catalyzes the ATP-dependent phosphorylation of cellobiose to produce cellobiose-6'-P. May have a dual role of kinase and transcriptional regulator of the cellobiose-PTS operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=270, Percent_Identity=25.1851851851852, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI298566325, Length=270, Percent_Identity=25.1851851851852, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4885285, Length=270, Percent_Identity=25.1851851851852, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI190014632, Length=270, Percent_Identity=25.1851851851852, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787363, Length=311, Percent_Identity=25.7234726688103, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081733, Length=311, Percent_Identity=24.7588424437299, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.85 [H]

Molecular weight: Translated: 32144; Mature: 32144

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEMKLFLAENTDVTGIAVS
CEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
APGYVNPKTGLITMGGAIRRFDNFNLKEWLEAETGIPVAIENDANCALLAEKWLGKGQNL
CCCCCCCCCCEEECCCHHHHCCCCCHHHHHHHCCCCCEEEECCCCEEEEEHHHCCCCCCC
DDFLCLTIGTGIGGGIFSNGALVRGGRFRAGEFGYMFSERPGAFRPGKYTLNETTTMLVL
CCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCCEECCCHHHHHHH
RRQYAELTGRPLEEITGEEIFAKYDGHDAVSERLITEFYTGICTGLYNLIYLFDPTHIFI
HHHHHHHCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEE
GGGITSRPTFITELKHHVESFGLRDTIIETATHKNQAGLLGAVYHFLQEENRHE
ECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEMKLFLAENTDVTGIAVS
CEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
APGYVNPKTGLITMGGAIRRFDNFNLKEWLEAETGIPVAIENDANCALLAEKWLGKGQNL
CCCCCCCCCCEEECCCHHHHCCCCCHHHHHHHCCCCCEEEECCCCEEEEEHHHCCCCCCC
DDFLCLTIGTGIGGGIFSNGALVRGGRFRAGEFGYMFSERPGAFRPGKYTLNETTTMLVL
CCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCCEECCCHHHHHHH
RRQYAELTGRPLEEITGEEIFAKYDGHDAVSERLITEFYTGICTGLYNLIYLFDPTHIFI
HHHHHHHCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEE
GGGITSRPTFITELKHHVESFGLRDTIIETATHKNQAGLLGAVYHFLQEENRHE
ECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669; 12110692 [H]