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The map label for this gene is chbC [H]

Identifier: 226225315

GI number: 226225315

Start: 2816776

End: 2818128

Strand: Direct

Name: chbC [H]

Synonym: Lm4b_02738

Alternate gene names: 226225315

Gene position: 2816776-2818128 (Clockwise)

Preceding gene: 226225314

Following gene: 226225316

Centisome position: 96.71

GC content: 40.87

Gene sequence:

>1353_bases
ATGAGTATAATGTCAAAATTTGAACACGGCATGGAACGTGTTTTAGTACCAGTTGCGAATAAATTGAACTCGCAGCGCCA
TATTGCAGCAATTCGTGATGCATTTATTTTAGTTTTCCCATTAATTATGGCTGGTTCAATTATCACTTTGATTAACTTCG
CAGTATTATCACCAGATGGCTTTATTGCAAAAATCTTATTCCTAGGGAAAATTTTCCCTAATTTAGCCGATGCACAGGCT
GTATTTTCGCCAGTAATGCAAGGTTCGACCAATATTATGGCCATTCTGATCGTATTCTTAGTCGCACGGAATCTCGCCAT
CTTCTTTAAACAGGATGATTTGCTCTGTGGACTGACCTCGATAGGTGCATTCTTTATCGTGTATACACCTTACACAGTAG
TTGACAATGCATCTTACATGACAATCAAATTCTTAGGAGCACAAGGTCTTTTCGTTGCTATTATTGTAGCGATTATTACT
GGGGAAGTATTTAGCCGTCTAGCTAGATCCCCTCGTTTAATGATCAAAATGCCTGACCAAGTACCACCAGCAGTTGCTCG
TTCTTTTAAAGTATTAATTCCAGTTATCATCATCACTATTCTTTTCTCTGTCATTAACTACTTAATCACTTTAATCGCTC
CAGAAGGTTTAAACGACCTTGTTTACACAGTTATTCAAGCGCCACTTAAAGACATGGGAACTAACGTATTCTCTGTAATT
ATCATCGGGCTTGTTTCTAACTTACTTTGGGTTCTTGGTATTCACGGGCCTAACACTGTTGCGGCTATTCGTGACACCAT
CTTCACTGAACCAAACTTAGATAACTTATCTTACGTAGCACAGCACGGTTCTGCTTGGGGAGCTCCATACCCAGCAACAT
GGGCTGGCCTAAATGACGGATTTGCAAACTACGGCGGATCTGGTATGACTCTAGGTTTACTGATTGCTATCTTTATCGCT
TCTCGTCGTGCAGACTACCGCGATATCGCGAAACTTTCTCTTGCACCAGGGATTTTCAACATCAATGAACCAGTTATTTT
CGGTTTACCAATCGTATTAAACCCAATTATGGTTATTCCTTTCATCATTACACCAGCAATCAATACATTAATTGGTTACT
TCTTTATCTCAACAAAACTTATTCCACCTGTCGCCTATCAAGTGCCTTGGACAACTCCAGGACCACTGATTCCATTCCTT
GGTACAGGAGGAAACTGGCTCGCGCTTCTGGTCGGCTTGCTCTGTCTAGCCGTCGCAACAGTCATTTATCTACCATTCGT
ACTTGTATCTAACAAAATTGCCGCGAGTGATGCTGCAATGGACAAAAATGCAACAGCCTCAACAGAACAATAG

Upstream 100 bases:

>100_bases
ATATGAAAGATTATGGTATGTTAAACGGGAAAGCCGTTCTTGAAAAAGCTTTCGCGGAGATTGGTTAAGGGAGATTCATT
CAAAATAGGGAGGTTTTAAA

Downstream 100 bases:

>100_bases
GATGTGACAAAATGAAAATTGCAGCTTTTGATATCGGTGGAACGGCCCTTAAAATGGGGGTCGTTTTGCCGCATGGTGAA
ATTATACTAACAAAATCCGC

Product: PTS cellobiose-specific enzyme IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSIMSKFEHGMERVLVPVANKLNSQRHIAAIRDAFILVFPLIMAGSIITLINFAVLSPDGFIAKILFLGKIFPNLADAQA
VFSPVMQGSTNIMAILIVFLVARNLAIFFKQDDLLCGLTSIGAFFIVYTPYTVVDNASYMTIKFLGAQGLFVAIIVAIIT
GEVFSRLARSPRLMIKMPDQVPPAVARSFKVLIPVIIITILFSVINYLITLIAPEGLNDLVYTVIQAPLKDMGTNVFSVI
IIGLVSNLLWVLGIHGPNTVAAIRDTIFTEPNLDNLSYVAQHGSAWGAPYPATWAGLNDGFANYGGSGMTLGLLIAIFIA
SRRADYRDIAKLSLAPGIFNINEPVIFGLPIVLNPIMVIPFIITPAINTLIGYFFISTKLIPPVAYQVPWTTPGPLIPFL
GTGGNWLALLVGLLCLAVATVIYLPFVLVSNKIAASDAAMDKNATASTEQ

Sequences:

>Translated_450_residues
MSIMSKFEHGMERVLVPVANKLNSQRHIAAIRDAFILVFPLIMAGSIITLINFAVLSPDGFIAKILFLGKIFPNLADAQA
VFSPVMQGSTNIMAILIVFLVARNLAIFFKQDDLLCGLTSIGAFFIVYTPYTVVDNASYMTIKFLGAQGLFVAIIVAIIT
GEVFSRLARSPRLMIKMPDQVPPAVARSFKVLIPVIIITILFSVINYLITLIAPEGLNDLVYTVIQAPLKDMGTNVFSVI
IIGLVSNLLWVLGIHGPNTVAAIRDTIFTEPNLDNLSYVAQHGSAWGAPYPATWAGLNDGFANYGGSGMTLGLLIAIFIA
SRRADYRDIAKLSLAPGIFNINEPVIFGLPIVLNPIMVIPFIITPAINTLIGYFFISTKLIPPVAYQVPWTTPGPLIPFL
GTGGNWLALLVGLLCLAVATVIYLPFVLVSNKIAASDAAMDKNATASTEQ
>Mature_449_residues
SIMSKFEHGMERVLVPVANKLNSQRHIAAIRDAFILVFPLIMAGSIITLINFAVLSPDGFIAKILFLGKIFPNLADAQAV
FSPVMQGSTNIMAILIVFLVARNLAIFFKQDDLLCGLTSIGAFFIVYTPYTVVDNASYMTIKFLGAQGLFVAIIVAIITG
EVFSRLARSPRLMIKMPDQVPPAVARSFKVLIPVIIITILFSVINYLITLIAPEGLNDLVYTVIQAPLKDMGTNVFSVII
IGLVSNLLWVLGIHGPNTVAAIRDTIFTEPNLDNLSYVAQHGSAWGAPYPATWAGLNDGFANYGGSGMTLGLLIAIFIAS
RRADYRDIAKLSLAPGIFNINEPVIFGLPIVLNPIMVIPFIITPAINTLIGYFFISTKLIPPVAYQVPWTTPGPLIPFLG
TGGNWLALLVGLLCLAVATVIYLPFVLVSNKIAASDAAMDKNATASTEQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=456, Percent_Identity=38.1578947368421, Blast_Score=253, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48569; Mature: 48438

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIMSKFEHGMERVLVPVANKLNSQRHIAAIRDAFILVFPLIMAGSIITLINFAVLSPDG
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FIAKILFLGKIFPNLADAQAVFSPVMQGSTNIMAILIVFLVARNLAIFFKQDDLLCGLTS
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
IGAFFIVYTPYTVVDNASYMTIKFLGAQGLFVAIIVAIITGEVFSRLARSPRLMIKMPDQ
HHHEEEEECCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
VPPAVARSFKVLIPVIIITILFSVINYLITLIAPEGLNDLVYTVIQAPLKDMGTNVFSVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHH
IIGLVSNLLWVLGIHGPNTVAAIRDTIFTEPNLDNLSYVAQHGSAWGAPYPATWAGLNDG
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
FANYGGSGMTLGLLIAIFIASRRADYRDIAKLSLAPGIFNINEPVIFGLPIVLNPIMVIP
HHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCCEECCHHHHHHHHHHH
FIITPAINTLIGYFFISTKLIPPVAYQVPWTTPGPLIPFLGTGGNWLALLVGLLCLAVAT
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VIYLPFVLVSNKIAASDAAMDKNATASTEQ
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SIMSKFEHGMERVLVPVANKLNSQRHIAAIRDAFILVFPLIMAGSIITLINFAVLSPDG
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FIAKILFLGKIFPNLADAQAVFSPVMQGSTNIMAILIVFLVARNLAIFFKQDDLLCGLTS
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
IGAFFIVYTPYTVVDNASYMTIKFLGAQGLFVAIIVAIITGEVFSRLARSPRLMIKMPDQ
HHHEEEEECCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
VPPAVARSFKVLIPVIIITILFSVINYLITLIAPEGLNDLVYTVIQAPLKDMGTNVFSVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHH
IIGLVSNLLWVLGIHGPNTVAAIRDTIFTEPNLDNLSYVAQHGSAWGAPYPATWAGLNDG
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
FANYGGSGMTLGLLIAIFIASRRADYRDIAKLSLAPGIFNINEPVIFGLPIVLNPIMVIP
HHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCCEECCHHHHHHHHHHH
FIITPAINTLIGYFFISTKLIPPVAYQVPWTTPGPLIPFLGTGGNWLALLVGLLCLAVAT
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VIYLPFVLVSNKIAASDAAMDKNATASTEQ
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]