Click here to switch to the map view.

The map label for this gene is yieK [H]

Identifier: 226225272

GI number: 226225272

Start: 2767032

End: 2767751

Strand: Reverse

Name: yieK [H]

Synonym: Lm4b_02695

Alternate gene names: 226225272

Gene position: 2767751-2767032 (Counterclockwise)

Preceding gene: 226225275

Following gene: 226225270

Centisome position: 95.02

GC content: 42.36

Gene sequence:

>720_bases
ATGAAAATTATTGTGGAAAAAGATTACGAAAATATGAGTAAAACAACGATGCAACTGCTTTTAGGGAAAATGTATCAAGA
CAAGTTGGTTCATTTAGCCATCACAGCAGGCTCCACACCGAAGCGAATGTACGAACTGATGGTAGAAGAAATGAAAGAAA
AGGCACCACTGACAAATGTAAGCTATTATAATTTTGACGAAATTCCAATTGGGGACGAAAAATACGGCGTAACCATTGCC
AATTTAAAAGCGATGTACTTTGATCCGGCGGGAATTCCAGAAGAACAAATTCACATGCTAGATACAAAAAACTATACAGA
CCATGAAGCGCATTTGAAAGCAGTTGGCGGTTTGGACGCGATTTTAATCGGGATTGGTGAAGATGGTCACTTCTGCGGGA
ACTTACCTGGCGTAACCAAATTCGGCGATGAAACCCGACTTGTTTCCGTTCAATCACGCCCAGATATGTTCGATATTTTG
CTCGGAGAAGTTGGCGGCGACGTGGAAAAAGTCCCCGAATACTACGTAACAATGGGACCAAAAAGCGTCATGCACGCAAA
AGAAGTCATCCTATTCGCAAACGGCAAGAAAAAAGCAGCGATTATCAAAAAAGCCCTACAAGGCCCAGTGACAGAAGACA
TTCCAAGCTCGATTTTCCAGTTACACCCTAATTTTACAGTGGTGCTGGACGAGGAAGCGGCGAGTGAGTTGAATATTTAA

Upstream 100 bases:

>100_bases
AATGGAAAAAAGCGGTTCCACATTTATCACCCTTTCGTCTTGACTCTATAGTTACTATACACTTTATCATAAAGGTAATT
CAAAGCGAGAGGTGAAAAAA

Downstream 100 bases:

>100_bases
AAGAAAACCCAACCTTCTATTTAGGAAGGCTGGGTTTTTGATTATCCATGCACACTAGCAAACTCCGCATCACGCAACTC
AACGCGACGAATTTTACCAG

Product: putative 6-phosphogluconolactonase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKIIVEKDYENMSKTTMQLLLGKMYQDKLVHLAITAGSTPKRMYELMVEEMKEKAPLTNVSYYNFDEIPIGDEKYGVTIA
NLKAMYFDPAGIPEEQIHMLDTKNYTDHEAHLKAVGGLDAILIGIGEDGHFCGNLPGVTKFGDETRLVSVQSRPDMFDIL
LGEVGGDVEKVPEYYVTMGPKSVMHAKEVILFANGKKKAAIIKKALQGPVTEDIPSSIFQLHPNFTVVLDEEAASELNI

Sequences:

>Translated_239_residues
MKIIVEKDYENMSKTTMQLLLGKMYQDKLVHLAITAGSTPKRMYELMVEEMKEKAPLTNVSYYNFDEIPIGDEKYGVTIA
NLKAMYFDPAGIPEEQIHMLDTKNYTDHEAHLKAVGGLDAILIGIGEDGHFCGNLPGVTKFGDETRLVSVQSRPDMFDIL
LGEVGGDVEKVPEYYVTMGPKSVMHAKEVILFANGKKKAAIIKKALQGPVTEDIPSSIFQLHPNFTVVLDEEAASELNI
>Mature_239_residues
MKIIVEKDYENMSKTTMQLLLGKMYQDKLVHLAITAGSTPKRMYELMVEEMKEKAPLTNVSYYNFDEIPIGDEKYGVTIA
NLKAMYFDPAGIPEEQIHMLDTKNYTDHEAHLKAVGGLDAILIGIGEDGHFCGNLPGVTKFGDETRLVSVQSRPDMFDIL
LGEVGGDVEKVPEYYVTMGPKSVMHAKEVILFANGKKKAAIIKKALQGPVTEDIPSSIFQLHPNFTVVLDEEAASELNI

Specific function: Unknown

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI19923881, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI13027378, Length=259, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=6e-17,
Organism=Escherichia coli, GI48994958, Length=230, Percent_Identity=50, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1786893, Length=226, Percent_Identity=26.5486725663717, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1789530, Length=231, Percent_Identity=22.5108225108225, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554876, Length=257, Percent_Identity=27.6264591439689, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24581960, Length=257, Percent_Identity=25.6809338521401, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920764, Length=257, Percent_Identity=25.6809338521401, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: NA

Molecular weight: Translated: 26541; Mature: 26541

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVEKDYENMSKTTMQLLLGKMYQDKLVHLAITAGSTPKRMYELMVEEMKEKAPLTNV
CEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
SYYNFDEIPIGDEKYGVTIANLKAMYFDPAGIPEEQIHMLDTKNYTDHEAHLKAVGGLDA
CEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHEEEECCCCCCCHHHHHHHHCCCEE
ILIGIGEDGHFCGNLPGVTKFGDETRLVSVQSRPDMFDILLGEVGGDVEKVPEYYVTMGP
EEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHCCCEEEECCC
KSVMHAKEVILFANGKKKAAIIKKALQGPVTEDIPSSIFQLHPNFTVVLDEEAASELNI
HHHHHHEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHEECCCEEEEECCCCHHCCCC
>Mature Secondary Structure
MKIIVEKDYENMSKTTMQLLLGKMYQDKLVHLAITAGSTPKRMYELMVEEMKEKAPLTNV
CEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
SYYNFDEIPIGDEKYGVTIANLKAMYFDPAGIPEEQIHMLDTKNYTDHEAHLKAVGGLDA
CEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHEEEECCCCCCCHHHHHHHHCCCEE
ILIGIGEDGHFCGNLPGVTKFGDETRLVSVQSRPDMFDILLGEVGGDVEKVPEYYVTMGP
EEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHCCCEEEECCC
KSVMHAKEVILFANGKKKAAIIKKALQGPVTEDIPSSIFQLHPNFTVVLDEEAASELNI
HHHHHHEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHEECCCEEEEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]