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The map label for this gene is tadA [H]

Identifier: 226225270

GI number: 226225270

Start: 2764748

End: 2765218

Strand: Reverse

Name: tadA [H]

Synonym: Lm4b_02693

Alternate gene names: 226225270

Gene position: 2765218-2764748 (Counterclockwise)

Preceding gene: 226225272

Following gene: 226225269

Centisome position: 94.94

GC content: 42.46

Gene sequence:

>471_bases
ATGGAACGAGCTTTCTTTATGCAACAAGCGCTTGAAGAAGCCGAGAAAGCACGAGATATTGGAGAAGTTCCAATTGGTGC
AGTCGTTGTTTTAGATGGAGAAATTATTGGGCGGGCGCATAATTTGCGTGAAACGAGCCAAAATGCAGTGACCCATGCGG
AGTTGCTTGCGATTCAAGATGCGTGTAAACATCAAAATTCATGGCGACTTAGCGGTGCAGAACTATACGTTACGCTAGAA
CCATGTCCGATGTGTAGCGGCGCCATTTTACTTTCGCGGATTGAAAAGGTTTATTACGGAGCCAAAGATCCAAAAGCGGG
AACAGCCGGATCGTTAATGAATTTACTCCAGGATGACCGATTTAATCATACGTGTGAAGTAGAAGCAGGATTAATGGAAA
AAGAAAGCAGCGAAATGTTAAGAAGTTTTTTCCAAGATCTACGAAAACGGAATAAATTGAATAGGTCTTAA

Upstream 100 bases:

>100_bases
ACTAAAGTGTTCCTGTGAAAGTTTGAGCAGATTATTCCTACATCCAATCCAAGCTATGCTAAAATAACAATGAGTGACTT
TTTAGAAATGAGGTGCATAG

Downstream 100 bases:

>100_bases
TGCTTATTGTAAGAAATCATACTTTTAAATCTTTCATTGTGAAATAAAAAGCAATAAGCCTTACCAACATTTACAGCCAG
ATAATAATTGCGAAAAATAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MERAFFMQQALEEAEKARDIGEVPIGAVVVLDGEIIGRAHNLRETSQNAVTHAELLAIQDACKHQNSWRLSGAELYVTLE
PCPMCSGAILLSRIEKVYYGAKDPKAGTAGSLMNLLQDDRFNHTCEVEAGLMEKESSEMLRSFFQDLRKRNKLNRS

Sequences:

>Translated_156_residues
MERAFFMQQALEEAEKARDIGEVPIGAVVVLDGEIIGRAHNLRETSQNAVTHAELLAIQDACKHQNSWRLSGAELYVTLE
PCPMCSGAILLSRIEKVYYGAKDPKAGTAGSLMNLLQDDRFNHTCEVEAGLMEKESSEMLRSFFQDLRKRNKLNRS
>Mature_156_residues
MERAFFMQQALEEAEKARDIGEVPIGAVVVLDGEIIGRAHNLRETSQNAVTHAELLAIQDACKHQNSWRLSGAELYVTLE
PCPMCSGAILLSRIEKVYYGAKDPKAGTAGSLMNLLQDDRFNHTCEVEAGLMEKESSEMLRSFFQDLRKRNKLNRS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=148, Percent_Identity=33.1081081081081, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=39.7350993377483, Blast_Score=120, Evalue=4e-29,
Organism=Escherichia coli, GI1786616, Length=156, Percent_Identity=30.1282051282051, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17554608, Length=106, Percent_Identity=44.3396226415094, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=34.2281879194631, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17555996, Length=120, Percent_Identity=35.8333333333333, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325319, Length=101, Percent_Identity=36.6336633663366, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=31.0810810810811, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17470; Mature: 17470

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERAFFMQQALEEAEKARDIGEVPIGAVVVLDGEIIGRAHNLRETSQNAVTHAELLAIQD
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACKHQNSWRLSGAELYVTLEPCPMCSGAILLSRIEKVYYGAKDPKAGTAGSLMNLLQDDR
HHCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
FNHTCEVEAGLMEKESSEMLRSFFQDLRKRNKLNRS
CCCEEECHHCHHCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERAFFMQQALEEAEKARDIGEVPIGAVVVLDGEIIGRAHNLRETSQNAVTHAELLAIQD
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACKHQNSWRLSGAELYVTLEPCPMCSGAILLSRIEKVYYGAKDPKAGTAGSLMNLLQDDR
HHCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
FNHTCEVEAGLMEKESSEMLRSFFQDLRKRNKLNRS
CCCEEECHHCHHCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]