Click here to switch to the map view.

The map label for this gene is ytlI [H]

Identifier: 226224897

GI number: 226224897

Start: 2383040

End: 2383939

Strand: Direct

Name: ytlI [H]

Synonym: Lm4b_02316

Alternate gene names: 226224897

Gene position: 2383040-2383939 (Clockwise)

Preceding gene: 226224883

Following gene: 226224913

Centisome position: 81.82

GC content: 38.89

Gene sequence:

>900_bases
TTGGAATTTCGAACCATTAAAACTTTTTATACGGTGGTTAATACGGGAAGTTTTCAACGCGCAGCAGAAGTATTAAATTA
TTCGCAACCGACTATTTCGATGCGAATTAAACAATTGGAACAAGACTTAGATGTTCAGTTATTCGAACGTGGCAAAACTT
TAAAACTAACGCACGCAGGTAGATTATTTTACGAAAGGGCGGGCCAGCTCATCGCTCAATATGAAGTACTCGATCACACG
ATATTCGACTTAAAAAATGGCAACGCCGGCCTTATCAAAGTTGGAATTTCCGAGCCTAGCGCTAGTCTCGTTTTTCCGAA
AATTTTAAAAACGTTTCTAGCGGATTTTCCAAAGTTAATGGTGAATGTATCGGTGGATGATGCGAATACTTGTAGCCAAA
AACTCATTGATGGGGAAATTGATTTTGCGATTTGCGGAGAACCAGAGCTAATTTTGGAGAACTTCTATTTTCCATTTTTC
CATGATTCGTTAGATTTAATCGTCTCAGAAAGCCATCCGTTAGCTTCACGTACTTCTGTGGAGTTACGTGATTTACGCGA
TGAATGCTTTATCTTCACACCGGCAAATTGCCCCATCCGCATCCAAATCGAACAGCATTTAAAACGTGCTATTGGTAGTG
ATTACAAAAAAATGGAGCTCACAAGTAGTATGTCACATAAGTATTTTGTTCGTGAAAATGTTGGTGTATCTATCTTTACT
AGCACCGCGCACTCAGAACTACTTGATGGCACGGTCCGCATTCCGATTGAAAATTTACCCATCTCACCGCCAATTGGACT
TTTAACTAACCAAAAAGAAAAAGATTTTGACAGCACGACGAAAGAACTTATCGACCGGATTATTTATTATTTTGATGATA
AAAAAAGACAGCTAGGCTAA

Upstream 100 bases:

>100_bases
ATTCCTATGAATTTTATCAGATTAATAAATTGCTTCTCCTATTTTTACAGTGTATACTGTTAGAAATATCAAAAAACTCC
AATATGAAGGGGGAATTATA

Downstream 100 bases:

>100_bases
AAAATTAGCTTAACTGTCTTTTTTATTAAAATTCTAATTGCATATTCGCCTCTATCGCAAGTAAATTATCACGATACACT
TTCATTTCTTTCCGCGTAAT

Product: LysR family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MEFRTIKTFYTVVNTGSFQRAAEVLNYSQPTISMRIKQLEQDLDVQLFERGKTLKLTHAGRLFYERAGQLIAQYEVLDHT
IFDLKNGNAGLIKVGISEPSASLVFPKILKTFLADFPKLMVNVSVDDANTCSQKLIDGEIDFAICGEPELILENFYFPFF
HDSLDLIVSESHPLASRTSVELRDLRDECFIFTPANCPIRIQIEQHLKRAIGSDYKKMELTSSMSHKYFVRENVGVSIFT
STAHSELLDGTVRIPIENLPISPPIGLLTNQKEKDFDSTTKELIDRIIYYFDDKKRQLG

Sequences:

>Translated_299_residues
MEFRTIKTFYTVVNTGSFQRAAEVLNYSQPTISMRIKQLEQDLDVQLFERGKTLKLTHAGRLFYERAGQLIAQYEVLDHT
IFDLKNGNAGLIKVGISEPSASLVFPKILKTFLADFPKLMVNVSVDDANTCSQKLIDGEIDFAICGEPELILENFYFPFF
HDSLDLIVSESHPLASRTSVELRDLRDECFIFTPANCPIRIQIEQHLKRAIGSDYKKMELTSSMSHKYFVRENVGVSIFT
STAHSELLDGTVRIPIENLPISPPIGLLTNQKEKDFDSTTKELIDRIIYYFDDKKRQLG
>Mature_299_residues
MEFRTIKTFYTVVNTGSFQRAAEVLNYSQPTISMRIKQLEQDLDVQLFERGKTLKLTHAGRLFYERAGQLIAQYEVLDHT
IFDLKNGNAGLIKVGISEPSASLVFPKILKTFLADFPKLMVNVSVDDANTCSQKLIDGEIDFAICGEPELILENFYFPFF
HDSLDLIVSESHPLASRTSVELRDLRDECFIFTPANCPIRIQIEQHLKRAIGSDYKKMELTSSMSHKYFVRENVGVSIFT
STAHSELLDGTVRIPIENLPISPPIGLLTNQKEKDFDSTTKELIDRIIYYFDDKKRQLG

Specific function: Positively regulates the expression of ytmI operon in response to the availability of sulfur sources [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=211, Percent_Identity=30.3317535545024, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693105, Length=249, Percent_Identity=27.3092369477912, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788481, Length=266, Percent_Identity=28.1954887218045, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790208, Length=212, Percent_Identity=31.1320754716981, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081904, Length=298, Percent_Identity=26.8456375838926, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788297, Length=226, Percent_Identity=25.2212389380531, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790399, Length=261, Percent_Identity=24.904214559387, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787879, Length=197, Percent_Identity=29.4416243654822, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=22.9249011857708, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI2367136, Length=199, Percent_Identity=29.1457286432161, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=140, Percent_Identity=30.7142857142857, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786508, Length=175, Percent_Identity=28, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082132, Length=246, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788887, Length=195, Percent_Identity=28.7179487179487, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=28.6885245901639, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=216, Percent_Identity=23.6111111111111, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=137, Percent_Identity=29.1970802919708, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787128, Length=129, Percent_Identity=28.6821705426357, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34085; Mature: 34085

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFRTIKTFYTVVNTGSFQRAAEVLNYSQPTISMRIKQLEQDLDVQLFERGKTLKLTHAG
CCCEEEEHEEHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHCCCEEEEEHHH
RLFYERAGQLIAQYEVLDHTIFDLKNGNAGLIKVGISEPSASLVFPKILKTFLADFPKLM
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VNVSVDDANTCSQKLIDGEIDFAICGEPELILENFYFPFFHDSLDLIVSESHPLASRTSV
EEEECCCCHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCH
ELRDLRDECFIFTPANCPIRIQIEQHLKRAIGSDYKKMELTSSMSHKYFVRENVGVSIFT
HHHHCCCCEEEEECCCCCEEEEHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCEEEEE
STAHSELLDGTVRIPIENLPISPPIGLLTNQKEKDFDSTTKELIDRIIYYFDDKKRQLG
CCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MEFRTIKTFYTVVNTGSFQRAAEVLNYSQPTISMRIKQLEQDLDVQLFERGKTLKLTHAG
CCCEEEEHEEHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHCCCEEEEEHHH
RLFYERAGQLIAQYEVLDHTIFDLKNGNAGLIKVGISEPSASLVFPKILKTFLADFPKLM
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VNVSVDDANTCSQKLIDGEIDFAICGEPELILENFYFPFFHDSLDLIVSESHPLASRTSV
EEEECCCCHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCH
ELRDLRDECFIFTPANCPIRIQIEQHLKRAIGSDYKKMELTSSMSHKYFVRENVGVSIFT
HHHHCCCCEEEEECCCCCEEEEHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCEEEEE
STAHSELLDGTVRIPIENLPISPPIGLLTNQKEKDFDSTTKELIDRIIYYFDDKKRQLG
CCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]