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The map label for this gene is yvyI [H]

Identifier: 226224716

GI number: 226224716

Start: 2190154

End: 2191110

Strand: Reverse

Name: yvyI [H]

Synonym: Lm4b_02132

Alternate gene names: 226224716

Gene position: 2191110-2190154 (Counterclockwise)

Preceding gene: 226224717

Following gene: 226224712

Centisome position: 75.23

GC content: 40.65

Gene sequence:

>957_bases
ATGACAGAAGCATTATTTTTAAACCCTGTTTTTCAAGACCGAATTTGGGGTGGAACGAAATTACATGATTATTTTGGTTA
CGATATCCCGTCTGATACTACTGGAGAAGACTGGGCGATTTCCGCTCATCCGAACGGTCCTTCGGTAATCAAAAACGGCG
AATATAAAGGCAAAACATTAGCTGAATTATGGCAAGAAAATCCTGCACTTTTTGGTAATCCGAAAGAAGCCGTTTTCCCA
CTATTAACGAAAATTTTGGATGCGAATACGGACCTTTCTGTACAAGTTCATCCAAATGACGAATATGCGAAAGTGCATGA
AAACGGGGAACTTGGCAAAACAGAATGCTGGTATATTATTGACTGCGCTCCGGGTGCGGAATTAATATATGGACACAAAG
CAGCTAGCAAAGAAGAATTCGCTACTTGGGCAAAAAACGGCGAATGGGATAAATTGCTTCGTAAAGTGGCGATTAAACCA
GGTGAATTTTATTATGTTCCAAGTGGTACAATTCATGCGTTAGGCACGGGGACGTTAGTGCTTGAAACACAACAAAGCTC
TGATACTACTTATCGTGTATATGACTATGACCGTAAAGACGCAGAAGGAAACTTGCGCGAACTTCATTTGGATAAAGCTA
TTGACGTTACGACTGCACCGCATGTGGATGCGAAGTTAGATATTAAAACAGAAACACGTGGTGGGTTGACTGAAACTACT
TTTGTATCGAATGATTTCTTTAGCGTATACAAATGGGAAGTGGACGGCGCGGCTGAATTCATGGCTAAAGCTCCTTATAC
GTTAGTGAGTGTTTTAGACGGAGAAGCGGTACTTACGATTGATGGAACAAAACAATCGATTAAAAAAGGCGATCATTTTG
TATTGCCGAATGATGTAAAATCTTGGGAAATTGATGGAAAAATGACGGCGATTGTTTCGAATCCGCCTGTGAAATAA

Upstream 100 bases:

>100_bases
GGCTTTTTAGGCGGGAAATAACTAGCATCTTCGCCATTATTAGTATATACTTTTAATTGACAAAACCCAGCAAAAACGCT
GGAATGGAGGTAATTTTATA

Downstream 100 bases:

>100_bases
CAAATAAGCAGAAATCATTGTATAAAAGCCATTTTGAAAATGGAATATACAAGATTTCTGCTTCTTTATTGCTTTATGAA
ATGACAACTAAAATATCATT

Product: mannnose-6 phospate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTEALFLNPVFQDRIWGGTKLHDYFGYDIPSDTTGEDWAISAHPNGPSVIKNGEYKGKTLAELWQENPALFGNPKEAVFP
LLTKILDANTDLSVQVHPNDEYAKVHENGELGKTECWYIIDCAPGAELIYGHKAASKEEFATWAKNGEWDKLLRKVAIKP
GEFYYVPSGTIHALGTGTLVLETQQSSDTTYRVYDYDRKDAEGNLRELHLDKAIDVTTAPHVDAKLDIKTETRGGLTETT
FVSNDFFSVYKWEVDGAAEFMAKAPYTLVSVLDGEAVLTIDGTKQSIKKGDHFVLPNDVKSWEIDGKMTAIVSNPPVK

Sequences:

>Translated_318_residues
MTEALFLNPVFQDRIWGGTKLHDYFGYDIPSDTTGEDWAISAHPNGPSVIKNGEYKGKTLAELWQENPALFGNPKEAVFP
LLTKILDANTDLSVQVHPNDEYAKVHENGELGKTECWYIIDCAPGAELIYGHKAASKEEFATWAKNGEWDKLLRKVAIKP
GEFYYVPSGTIHALGTGTLVLETQQSSDTTYRVYDYDRKDAEGNLRELHLDKAIDVTTAPHVDAKLDIKTETRGGLTETT
FVSNDFFSVYKWEVDGAAEFMAKAPYTLVSVLDGEAVLTIDGTKQSIKKGDHFVLPNDVKSWEIDGKMTAIVSNPPVK
>Mature_317_residues
TEALFLNPVFQDRIWGGTKLHDYFGYDIPSDTTGEDWAISAHPNGPSVIKNGEYKGKTLAELWQENPALFGNPKEAVFPL
LTKILDANTDLSVQVHPNDEYAKVHENGELGKTECWYIIDCAPGAELIYGHKAASKEEFATWAKNGEWDKLLRKVAIKPG
EFYYVPSGTIHALGTGTLVLETQQSSDTTYRVYDYDRKDAEGNLRELHLDKAIDVTTAPHVDAKLDIKTETRGGLTETTF
VSNDFFSVYKWEVDGAAEFMAKAPYTLVSVLDGEAVLTIDGTKQSIKKGDHFVLPNDVKSWEIDGKMTAIVSNPPVK

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 35337; Mature: 35206

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEALFLNPVFQDRIWGGTKLHDYFGYDIPSDTTGEDWAISAHPNGPSVIKNGEYKGKTL
CCCEEEECCHHHHHCCCCCEEEHHCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCHH
AELWQENPALFGNPKEAVFPLLTKILDANTDLSVQVHPNDEYAKVHENGELGKTECWYII
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEE
DCAPGAELIYGHKAASKEEFATWAKNGEWDKLLRKVAIKPGEFYYVPSGTIHALGTGTLV
ECCCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCEEEEEECCEEE
LETQQSSDTTYRVYDYDRKDAEGNLRELHLDKAIDVTTAPHVDAKLDIKTETRGGLTETT
EEECCCCCCEEEEEECCCCCCCCCCEEEEECCCEEEECCCCCCEEEEEEECCCCCCEEEE
FVSNDFFSVYKWEVDGAAEFMAKAPYTLVSVLDGEAVLTIDGTKQSIKKGDHFVLPNDVK
EECCCCEEEEEEEECCHHHHHHCCCEEEEEEECCCEEEEECCCHHHHHCCCCEEECCCCC
SWEIDGKMTAIVSNPPVK
CEEECCEEEEEECCCCCC
>Mature Secondary Structure 
TEALFLNPVFQDRIWGGTKLHDYFGYDIPSDTTGEDWAISAHPNGPSVIKNGEYKGKTL
CCEEEECCHHHHHCCCCCEEEHHCCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCHH
AELWQENPALFGNPKEAVFPLLTKILDANTDLSVQVHPNDEYAKVHENGELGKTECWYII
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEE
DCAPGAELIYGHKAASKEEFATWAKNGEWDKLLRKVAIKPGEFYYVPSGTIHALGTGTLV
ECCCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCEEEEEECCEEE
LETQQSSDTTYRVYDYDRKDAEGNLRELHLDKAIDVTTAPHVDAKLDIKTETRGGLTETT
EEECCCCCCEEEEEECCCCCCCCCCEEEEECCCEEEECCCCCCEEEEEEECCCCCCEEEE
FVSNDFFSVYKWEVDGAAEFMAKAPYTLVSVLDGEAVLTIDGTKQSIKKGDHFVLPNDVK
EECCCCEEEEEEEECCHHHHHHCCCEEEEEEECCCEEEEECCCHHHHHCCCCEEECCCCC
SWEIDGKMTAIVSNPPVK
CEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934877; 7581999; 9384377 [H]