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The map label for this gene is mraY

Identifier: 226224643

GI number: 226224643

Start: 2118446

End: 2119420

Strand: Reverse

Name: mraY

Synonym: Lm4b_02058

Alternate gene names: 226224643

Gene position: 2119420-2118446 (Counterclockwise)

Preceding gene: 226224644

Following gene: 226224642

Centisome position: 72.77

GC content: 37.33

Gene sequence:

>975_bases
GTGTCTTTATACATGTTAGTATCAACATTTGCAGTTGCTTTTATCATTACGGTGATAGGTGTACCACTATTTATACCATT
CTTGGTGAAATTAAAATTCGGCCAAAGTATTAGAGATGAAGGTCCGAAAATGCATGAAAAGAAATCAGGGACACCGACAA
TGGGGGCAGTTGTTTTCATTACTGCAATGCTTATTAGTTTCTTGATCTTTTCGTTCATCAGTGGTGAAGTTAGTGCAGCT
ACGTGGCTGCTATTCATCGCGCTGGCACTATTTGGCGCATTAGGTTTCCTAGATGACTATATCAAAGTAGTTCAAAAACG
TAATCTAGGCCTTACTTCAAAGCAGAAGTTTTTAGGTCAAGTGGCAATTTCGATTTTATTCTATCTGGTATATCATTTAA
ATGGTTTTGCTGAGACGCTTAATATTCCGTTTACAAATATAGAAGTGGATCTTGGTTGGTTCTTTGTTATCTTTATTTTG
TTCTGGTTAGTTGGTTTCTCTAATGCAGTTAATTTAACAGATGGTTTAGATGGTCTTGTCTCTGGCCTTTCTGTCATTGC
TTTTTCTGCTTTTGGTGTCATTGCATTTTACCAAGAACAAATGGATGTCGCGATTTTCTGTTTTGCGATTGTGGGCGGTA
TGCTTGGATTTCTACTATTTAATAAAAATCCAGCGAAAATCTTCATGGGAGATACTGGTTCGCTTGCACTCGGTGGAAGT
ATCGCCGCAATTTCTATTTTAGTACATCAAGAATGGCTGTTACTCTTAATCGGAATTATTTTCGTTATTGAAACAGCATC
TGTTATATTGCAAGTATTTTATTTTAAGGCAACTGGAGGAAAACGAATCTTCCGTATGACACCAATTCATCATCACTTTG
AACTTGGTGGCTGGTCCGAATGGCGTGTTGTTTTAACGTTCTGGGGAATCGGGTTAATCGGAGCAATTATTTCTGTCTGT
GTAGTCATTTTTTAA

Upstream 100 bases:

>100_bases
GATGACCGAGTAGAAGCCCGAATAGCTATTGAAAAAAAACTTGGACTCGCATAAAATATGAAGTGAAGTGCTTTGACAAA
CAGATTGGGGAGAATTTATT

Downstream 100 bases:

>100_bases
ATAATGCGCCGTAATCTTTTTACGGCAAAAGCGTCTCTAGTTAGCTGTTTTTTTACAGAATCTGGTTGGCGCTTTCCGTC
GTTTTTGTGAAAATCATAAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSLYMLVSTFAVAFIITVIGVPLFIPFLVKLKFGQSIRDEGPKMHEKKSGTPTMGAVVFITAMLISFLIFSFISGEVSAA
TWLLFIALALFGALGFLDDYIKVVQKRNLGLTSKQKFLGQVAISILFYLVYHLNGFAETLNIPFTNIEVDLGWFFVIFIL
FWLVGFSNAVNLTDGLDGLVSGLSVIAFSAFGVIAFYQEQMDVAIFCFAIVGGMLGFLLFNKNPAKIFMGDTGSLALGGS
IAAISILVHQEWLLLLIGIIFVIETASVILQVFYFKATGGKRIFRMTPIHHHFELGGWSEWRVVLTFWGIGLIGAIISVC
VVIF

Sequences:

>Translated_324_residues
MSLYMLVSTFAVAFIITVIGVPLFIPFLVKLKFGQSIRDEGPKMHEKKSGTPTMGAVVFITAMLISFLIFSFISGEVSAA
TWLLFIALALFGALGFLDDYIKVVQKRNLGLTSKQKFLGQVAISILFYLVYHLNGFAETLNIPFTNIEVDLGWFFVIFIL
FWLVGFSNAVNLTDGLDGLVSGLSVIAFSAFGVIAFYQEQMDVAIFCFAIVGGMLGFLLFNKNPAKIFMGDTGSLALGGS
IAAISILVHQEWLLLLIGIIFVIETASVILQVFYFKATGGKRIFRMTPIHHHFELGGWSEWRVVLTFWGIGLIGAIISVC
VVIF
>Mature_323_residues
SLYMLVSTFAVAFIITVIGVPLFIPFLVKLKFGQSIRDEGPKMHEKKSGTPTMGAVVFITAMLISFLIFSFISGEVSAAT
WLLFIALALFGALGFLDDYIKVVQKRNLGLTSKQKFLGQVAISILFYLVYHLNGFAETLNIPFTNIEVDLGWFFVIFILF
WLVGFSNAVNLTDGLDGLVSGLSVIAFSAFGVIAFYQEQMDVAIFCFAIVGGMLGFLLFNKNPAKIFMGDTGSLALGGSI
AAISILVHQEWLLLLIGIIFVIETASVILQVFYFKATGGKRIFRMTPIHHHFELGGWSEWRVVLTFWGIGLIGAIISVCV
VIF

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=339, Percent_Identity=41.5929203539823, Blast_Score=230, Evalue=9e-62,
Organism=Escherichia coli, GI1790218, Length=205, Percent_Identity=28.2926829268293, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35676; Mature: 35545

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYMLVSTFAVAFIITVIGVPLFIPFLVKLKFGQSIRDEGPKMHEKKSGTPTMGAVVFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHCCCCCCHHHHHHHH
TAMLISFLIFSFISGEVSAATWLLFIALALFGALGFLDDYIKVVQKRNLGLTSKQKFLGQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VAISILFYLVYHLNGFAETLNIPFTNIEVDLGWFFVIFILFWLVGFSNAVNLTDGLDGLV
HHHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
SGLSVIAFSAFGVIAFYQEQMDVAIFCFAIVGGMLGFLLFNKNPAKIFMGDTGSLALGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCH
IAAISILVHQEWLLLLIGIIFVIETASVILQVFYFKATGGKRIFRMTPIHHHFELGGWSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCCH
WRVVLTFWGIGLIGAIISVCVVIF
HHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SLYMLVSTFAVAFIITVIGVPLFIPFLVKLKFGQSIRDEGPKMHEKKSGTPTMGAVVFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHCCCCCCHHHHHHHH
TAMLISFLIFSFISGEVSAATWLLFIALALFGALGFLDDYIKVVQKRNLGLTSKQKFLGQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VAISILFYLVYHLNGFAETLNIPFTNIEVDLGWFFVIFILFWLVGFSNAVNLTDGLDGLV
HHHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
SGLSVIAFSAFGVIAFYQEQMDVAIFCFAIVGGMLGFLLFNKNPAKIFMGDTGSLALGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCH
IAAISILVHQEWLLLLIGIIFVIETASVILQVFYFKATGGKRIFRMTPIHHHFELGGWSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCCCH
WRVVLTFWGIGLIGAIISVCVVIF
HHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]