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The map label for this gene is deoD

Identifier: 226224459

GI number: 226224459

Start: 1918581

End: 1919282

Strand: Reverse

Name: deoD

Synonym: Lm4b_01872

Alternate gene names: 226224459

Gene position: 1919282-1918581 (Counterclockwise)

Preceding gene: 226224460

Following gene: 226224458

Centisome position: 65.89

GC content: 37.61

Gene sequence:

>702_bases
ATGAGCGTACATATCGAAGCAAAACAAGGGGAAATTGCAGAAACTATTTTATTACCAGGAGATCCATTGAGAGCAAAATA
TATTGCGGAAACATTTTTGGAAGATGTCGTTTTATTCAACCAAGTGCGAGGCATGTTAGGATTTACTGGTACATACAAAG
GCGAAAAAGTTTCTGTTATGGGAACTGGTATGGGAATTCCATCTATTTCGATTTATGTAAATGAATTAATTCAAAGCTAT
GATGTGAAAAACTTGATTCGCGTTGGTACTATGGGCGGCATTCAAGCAGATGTAAAAGTACGTGATGTTGTCATTGCACA
AGCGGCATCAACGGATTCGCAAATTAATCGCAATACTTTTGCTGGCGTAGATTTTGCACCAGTAGCTGATTTTTCTCTTC
TAAAAAAAGCGTATGATGCAGGTATCGAAAAAGGATTATCGCTTAAAGTTGGGAATGTTTTTTCTGCAGACCGTTTTTAT
AATGATCAACTAGACAAACAACAATTAGCAGACTATGGTGTGCTTGGAATTGAAATGGAAGCAGCGGCACTTTATACGTT
AGCACAAAAATATGGTCGTCGTGCTTTAGCTATTTTAACTGTAAGTGACCATATTTTCACTGGGGAAGAAACATCCGCGG
AAGAGCGCCAAACTACTTTCAATGATATGATTGTTGTAGCACTTGAAGCAGCAATAAAATAA

Upstream 100 bases:

>100_bases
AGTTTAATGCGCCGTATTTACCGGGAATGTCTATTTTTGATGAACTTTGGGATGCTTATTTGCTAGATGAAGAGAAAAAC
AAACACTAGGAGGAAAAAAG

Downstream 100 bases:

>100_bases
TTTTAATTACTAACTTAGAATTAGACTTAATGTATACAGGAAGGTTGATAAACAGATATGAGTTCTTTATTAACAATTGC
TTTAGCTGTTAGCATCAGTT

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVMGTGMGIPSISIYVNELIQSY
DVKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTFAGVDFAPVADFSLLKKAYDAGIEKGLSLKVGNVFSADRFY
NDQLDKQQLADYGVLGIEMEAAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK

Sequences:

>Translated_233_residues
MSVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVMGTGMGIPSISIYVNELIQSY
DVKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTFAGVDFAPVADFSLLKKAYDAGIEKGLSLKVGNVFSADRFY
NDQLDKQQLADYGVLGIEMEAAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK
>Mature_232_residues
SVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVMGTGMGIPSISIYVNELIQSYD
VKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTFAGVDFAPVADFSLLKKAYDAGIEKGLSLKVGNVFSADRFYN
DQLDKQQLADYGVLGIEMEAAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=230, Percent_Identity=57.3913043478261, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI1790265, Length=230, Percent_Identity=29.5652173913043, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25357; Mature: 25226

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVM
CEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GTGMGIPSISIYVNELIQSYDVKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCEECCEEEEEEEECCCCCCCCCCCCCC
AGVDFAPVADFSLLKKAYDAGIEKGLSLKVGNVFSADRFYNDQLDKQQLADYGVLGIEME
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCEECCHHHHCCCCCHHHHHHCCEEEEEHH
AAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK
HHHHHHHHHHHCCEEEEEEEEECEEECCCCCCHHHHHHHHHHHHHEEEEHHCC
>Mature Secondary Structure 
SVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVM
EEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GTGMGIPSISIYVNELIQSYDVKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCEECCEEEEEEEECCCCCCCCCCCCCC
AGVDFAPVADFSLLKKAYDAGIEKGLSLKVGNVFSADRFYNDQLDKQQLADYGVLGIEME
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCEECCHHHHCCCCCHHHHHHCCEEEEEHH
AAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK
HHHHHHHHHHHCCEEEEEEEEECEEECCCCCCHHHHHHHHHHHHHEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]