Click here to switch to the map view.

The map label for this gene is sugE [H]

Identifier: 226223471

GI number: 226223471

Start: 892213

End: 892554

Strand: Direct

Name: sugE [H]

Synonym: Lm4b_00869

Alternate gene names: 226223471

Gene position: 892213-892554 (Clockwise)

Preceding gene: 226223470

Following gene: 226223472

Centisome position: 30.63

GC content: 38.6

Gene sequence:

>342_bases
TTGGCTTGGTTTTATTTAATTATGGCAGGATTATCAGAAATTGTTTGGGCTTTTGGACTAAAAGAATCGCATGGTTTCAC
GATGTTAGGGTGGAGCCTTTTGACGATAGCATTTTTGATAGTTAGTTTTGGTTTGTTTTCGATTTCCATGAAGTCCATTC
CAATTGGGACGGCGTATGCGGTTTTTACTGGAATTGGGGCTGCTGGGACAGCGATTATTGGGATGATTTTCCTTTCAGAA
GGTGTTTCTTTTTGGAAGATTGTTTCGCTTATCGTATTATTAACAGGGATTATTGGTTTGAAATTAGTGGACGGCAATGA
GTCTGAAAAGGAGGCTAAATAA

Upstream 100 bases:

>100_bases
GTGGAACACGGCATTTATGATGAAACGGAATTTGAGTTGCGAAGAAAATCTGCTTGGGCAGTTCTCGCAAGTTTACTCAA
ATGAATTGGAGGTAAGGAAA

Downstream 100 bases:

>100_bases
CGATGGATTGGATATTTTTACTCGTAGCAGGTTTATGCGAAATGGTCTTCGTTGTCATGCTAAAATTATCAGATGGCTTT
AAAAAGGTTGGATATGCGAT

Product: SugE protein (transmembrane chaperone)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MAWFYLIMAGLSEIVWAFGLKESHGFTMLGWSLLTIAFLIVSFGLFSISMKSIPIGTAYAVFTGIGAAGTAIIGMIFLSE
GVSFWKIVSLIVLLTGIIGLKLVDGNESEKEAK

Sequences:

>Translated_113_residues
MAWFYLIMAGLSEIVWAFGLKESHGFTMLGWSLLTIAFLIVSFGLFSISMKSIPIGTAYAVFTGIGAAGTAIIGMIFLSE
GVSFWKIVSLIVLLTGIIGLKLVDGNESEKEAK
>Mature_112_residues
AWFYLIMAGLSEIVWAFGLKESHGFTMLGWSLLTIAFLIVSFGLFSISMKSIPIGTAYAVFTGIGAAGTAIIGMIFLSEG
VSFWKIVSLIVLLTGIIGLKLVDGNESEKEAK

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=51.9607843137255, Blast_Score=103, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12127; Mature: 11995

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFYLIMAGLSEIVWAFGLKESHGFTMLGWSLLTIAFLIVSFGLFSISMKSIPIGTAYA
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VFTGIGAAGTAIIGMIFLSEGVSFWKIVSLIVLLTGIIGLKLVDGNESEKEAK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
>Mature Secondary Structure 
AWFYLIMAGLSEIVWAFGLKESHGFTMLGWSLLTIAFLIVSFGLFSISMKSIPIGTAYA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VFTGIGAAGTAIIGMIFLSEGVSFWKIVSLIVLLTGIIGLKLVDGNESEKEAK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]