Click here to switch to the map view.

The map label for this gene is sugE [H]

Identifier: 226223472

GI number: 226223472

Start: 892557

End: 892877

Strand: Direct

Name: sugE [H]

Synonym: Lm4b_00870

Alternate gene names: 226223472

Gene position: 892557-892877 (Clockwise)

Preceding gene: 226223471

Following gene: 226223473

Centisome position: 30.64

GC content: 38.63

Gene sequence:

>321_bases
ATGGATTGGATATTTTTACTCGTAGCAGGTTTATGCGAAATGGTCTTCGTTGTCATGCTAAAATTATCAGATGGCTTTAA
AAAGGTTGGATATGCGATACTGACGATTATTTTTATGTCTGCAAGTTTCTTTTTACTATCCCTCGCGCTTAAGACGATTC
CAATCGGTACAGGTTATGCGATTTGGACCGGAATTGGTGCCGTTGGTAGTGTGACACTTGGAATGATTGTTTTTAAAGAA
CGTAAAAGTGTCGGCAAATTGCTCTTTATTACGATGATTATTGCCGGCGTGGTCGGTTTGAAATTAACATCTGGTGTTTA
A

Upstream 100 bases:

>100_bases
TTTCTTTTTGGAAGATTGTTTCGCTTATCGTATTATTAACAGGGATTATTGGTTTGAAATTAGTGGACGGCAATGAGTCT
GAAAAGGAGGCTAAATAACG

Downstream 100 bases:

>100_bases
TATTTTAGGTTGAAAAAGTCCTTTTTGGAATAAGCGTGCACGGTTCTTATTTAAAAAAGAAGATTTTTTCAACCTATTTT
TTAGTTATACCTTTTCATCC

Product: SugE protein (transmembrane chaperone)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MDWIFLLVAGLCEMVFVVMLKLSDGFKKVGYAILTIIFMSASFFLLSLALKTIPIGTGYAIWTGIGAVGSVTLGMIVFKE
RKSVGKLLFITMIIAGVVGLKLTSGV

Sequences:

>Translated_106_residues
MDWIFLLVAGLCEMVFVVMLKLSDGFKKVGYAILTIIFMSASFFLLSLALKTIPIGTGYAIWTGIGAVGSVTLGMIVFKE
RKSVGKLLFITMIIAGVVGLKLTSGV
>Mature_106_residues
MDWIFLLVAGLCEMVFVVMLKLSDGFKKVGYAILTIIFMSASFFLLSLALKTIPIGTGYAIWTGIGAVGSVTLGMIVFKE
RKSVGKLLFITMIIAGVVGLKLTSGV

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=41.3461538461538, Blast_Score=91, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11353; Mature: 11353

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWIFLLVAGLCEMVFVVMLKLSDGFKKVGYAILTIIFMSASFFLLSLALKTIPIGTGYA
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGAVGSVTLGMIVFKERKSVGKLLFITMIIAGVVGLKLTSGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDWIFLLVAGLCEMVFVVMLKLSDGFKKVGYAILTIIFMSASFFLLSLALKTIPIGTGYA
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGAVGSVTLGMIVFKERKSVGKLLFITMIIAGVVGLKLTSGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]