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The map label for this gene is ywaC [H]

Identifier: 226223419

GI number: 226223419

Start: 829965

End: 830603

Strand: Direct

Name: ywaC [H]

Synonym: Lm4b_00817

Alternate gene names: 226223419

Gene position: 829965-830603 (Clockwise)

Preceding gene: 226223418

Following gene: 226223420

Centisome position: 28.49

GC content: 33.96

Gene sequence:

>639_bases
ATGGAACAACCATCAGTAGATGAGCTAAAAAATTGGCGAAATGTTATGCTTCTTCACCGTTTTGCGTTAGAAGAAGTCAA
CACGAAACTTAAGATATTGAATGAAGAATTTCAATTTATTCATGATTATAATCCAATGGAACATTTGAAGTCACGTGTGA
AGTCACTAGAAAGTATCGGAGCAAAATTAGAAAAGAAAAAGGTGGATATCACGCCAGAAAATGCACTAAAATATGTACAC
GATATTGCGGGCATTCGGATTACTTGTTCTTTTGTTTCAGATATTTTTAGAATTCACGAAATGCTTGCAGGGCAAAGTGA
TATCACTATCAAACGAGTAAAGGACTATGTAACGAATCCAAAACCTAATGGCTATCGGAGTTTACATTTACTTTGCGAAG
TACCTGTATTCCTGACAAATCGTTCCGAGAAAATGACCGTGGAAATCCAAATTCGGACAGTTGCCATGGATTTTTGGGCG
AGTTTGGAGCATAAAATTTATTATAAATATCAACAAGAAGCACCAATTGAGTTAGTAAAAGAATTACAAGACGCCGCACG
AATTATCACCCATTTAGATGAAAAAATGAAAAACTTAAACGATCAAATTGATCAATATAAAAAAGAAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
TTCATGAGAAAGTGGTGAAACTTTAGACATATAGTTACACTGACCTCGGTTTTGTAGTAACATGGAATAGGAAGTTTATA
CATATGGAAGGAGTGTCCTC

Downstream 100 bases:

>100_bases
TCTAATAGGGAGCTTTATTTCTTTGCAAGCGGGATGGATGCATAGAAATAAAGCTGTTTTATATTTGCGAGTTAGGTTAT
TTTGCTTCATAATAATATAG

Product: GTP-pyrophosphokinase

Products: NA

Alternate protein names: (p)ppGpp synthase ywaC; Small alarmone synthase 2; SAS 2 [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MEQPSVDELKNWRNVMLLHRFALEEVNTKLKILNEEFQFIHDYNPMEHLKSRVKSLESIGAKLEKKKVDITPENALKYVH
DIAGIRITCSFVSDIFRIHEMLAGQSDITIKRVKDYVTNPKPNGYRSLHLLCEVPVFLTNRSEKMTVEIQIRTVAMDFWA
SLEHKIYYKYQQEAPIELVKELQDAARIITHLDEKMKNLNDQIDQYKKEKEK

Sequences:

>Translated_212_residues
MEQPSVDELKNWRNVMLLHRFALEEVNTKLKILNEEFQFIHDYNPMEHLKSRVKSLESIGAKLEKKKVDITPENALKYVH
DIAGIRITCSFVSDIFRIHEMLAGQSDITIKRVKDYVTNPKPNGYRSLHLLCEVPVFLTNRSEKMTVEIQIRTVAMDFWA
SLEHKIYYKYQQEAPIELVKELQDAARIITHLDEKMKNLNDQIDQYKKEKEK
>Mature_212_residues
MEQPSVDELKNWRNVMLLHRFALEEVNTKLKILNEEFQFIHDYNPMEHLKSRVKSLESIGAKLEKKKVDITPENALKYVH
DIAGIRITCSFVSDIFRIHEMLAGQSDITIKRVKDYVTNPKPNGYRSLHLLCEVPVFLTNRSEKMTVEIQIRTVAMDFWA
SLEHKIYYKYQQEAPIELVKELQDAARIITHLDEKMKNLNDQIDQYKKEKEK

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in respo

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007685 [H]

Pfam domain/function: PF04607 RelA_SpoT [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 25046; Mature: 25046

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPSVDELKNWRNVMLLHRFALEEVNTKLKILNEEFQFIHDYNPMEHLKSRVKSLESIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AKLEKKKVDITPENALKYVHDIAGIRITCSFVSDIFRIHEMLAGQSDITIKRVKDYVTNP
HHHHHCCCCCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
KPNGYRSLHLLCEVPVFLTNRSEKMTVEIQIRTVAMDFWASLEHKIYYKYQQEAPIELVK
CCCCHHHHHHHEECCHHEECCCCEEEEEEEEEHHHHHHHHHHHHHEEEEECCCCHHHHHH
ELQDAARIITHLDEKMKNLNDQIDQYKKEKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQPSVDELKNWRNVMLLHRFALEEVNTKLKILNEEFQFIHDYNPMEHLKSRVKSLESIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AKLEKKKVDITPENALKYVHDIAGIRITCSFVSDIFRIHEMLAGQSDITIKRVKDYVTNP
HHHHHCCCCCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
KPNGYRSLHLLCEVPVFLTNRSEKMTVEIQIRTVAMDFWASLEHKIYYKYQQEAPIELVK
CCCCHHHHHHHEECCHHEECCCCEEEEEEEEEHHHHHHHHHHHHHEEEEECCCCHHHHHH
ELQDAARIITHLDEKMKNLNDQIDQYKKEKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]