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The map label for this gene is (cry22Aa [H]

Identifier: 226223021

GI number: 226223021

Start: 421111

End: 422334

Strand: Direct

Name: (cry22Aa [H]

Synonym: Lm4b_00415

Alternate gene names: 226223021

Gene position: 421111-422334 (Clockwise)

Preceding gene: 226223019

Following gene: 226223022

Centisome position: 14.46

GC content: 35.87

Gene sequence:

>1224_bases
ATGAAAAAAATAATCGCGTTAATCACAGCAGTTGCACTTCTATCAATGATTGGATTTGCCTTTATCCCTGGTACTGTTGC
GAATGCAGCGAATTCATCAGAAAGCAGTTTAACATACAAAGATGTACGCAGTGGATTTTACTTTGTTGGTTATGAAAATG
TACAACTTGAAACAGGAAAAACATACAAGTACACAGTAGCGTATGAAGCAAATGTTGATATGAAAATGACAGATACTATT
ACAGGACAATCAGCAAAAGCAGGACTTTTTACACCAAAATCATCCGGTGCCGAGCTGAACACTAGTTACGTAAGCCGAAC
AAAGAATAACGTTATAGACGTAGCTGATGCAGGTAATAAGGTTTTTAAACACACATTTGAATTTACAGCGAAGGAAAATA
CAAAAGCAGATATCGGTGTTTTCTTAGGAGCAGGTTCTGTTCTTCCAACAACTCCAGAAACCACGTCCCTTTGGAAAAAC
GTAACCGTGACAAATGAAACTCCACTAGTACAAGCGGAGGCTCCAGTTATTAGTGCAGAAGATAAAACTATCAATCAAAA
TGAAAGTTTTAATCCACTAAATGAAGTCACTGCGTCAGACGAAAAAGACGGTGATATTACAAAGGACATCCACGTAACCA
AAAATACGGTAGATACGACTAAGAGTGGCAAATATGATGTGGATTATAGCGTTACAAATTCAAGCAACTTAACAACGACA
AAAAGTATTAAAGTAACCGTAACCCCAGCAGCAATAAGCAAAAATACAGCCCCAGTTATTAATGCAAAAGATCAAACAAT
CAAAGTTGGAGATGTGTTTAATGTGTTAAAAGGAGTTACTGCGAAAGATAACGAAGATGGTGATTTAACAGCAAAAATCA
AAGTGACCAAGGATACAGTGAATAATTCGAAAAAAGGTGTTTATCAAGTTACATATACTGTGACAGATTCTGGCAATCTA
TCAGCTTCACTTACAATTAAAGTGACTGTAACTCAAGATGGAAAACTAATAGTAAATCCAAGTGATCCAACAAAGCCATC
TATCACAAAAACACCTGTGGAACCAACAAAAATTGAAAAAGATCCTGAAAATAGAGCGACTTCCGTTTTGAAAGCAAGTA
AAATACCAAAAACTGGTGATAGTTCAATGATATGGCTAGTATTTGTCGGACTCGGCTTAACAGCTATTGGTATTAGTTCT
TATCAAAAAAAAGCAAATAAATAA

Upstream 100 bases:

>100_bases
CTTTGGTTAATTGCCAATTAGAATAAGTTGAAATATAGGGTTAAGGCTAACTTAACCCTATTTTCTAATTAAAGATGTAA
ATAAGGAGGATTTTAAATCC

Downstream 100 bases:

>100_bases
TGCATACTGGATGAAAAGAGTATTTTAGATTAGATACTCTTTTCATTAACTAGATGGTAAAATGGCATTCTAAAGCTGTT
TTTAAACAGCTTTATAGAGA

Product: cell surface protein (LPXTG motif)

Products: NA

Alternate protein names: 79 kDa crystal protein; Crystaline entomocidal protoxin; Insecticidal delta-endotoxin CryXXIIA(a) [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKKIIALITAVALLSMIGFAFIPGTVANAANSSESSLTYKDVRSGFYFVGYENVQLETGKTYKYTVAYEANVDMKMTDTI
TGQSAKAGLFTPKSSGAELNTSYVSRTKNNVIDVADAGNKVFKHTFEFTAKENTKADIGVFLGAGSVLPTTPETTSLWKN
VTVTNETPLVQAEAPVISAEDKTINQNESFNPLNEVTASDEKDGDITKDIHVTKNTVDTTKSGKYDVDYSVTNSSNLTTT
KSIKVTVTPAAISKNTAPVINAKDQTIKVGDVFNVLKGVTAKDNEDGDLTAKIKVTKDTVNNSKKGVYQVTYTVTDSGNL
SASLTIKVTVTQDGKLIVNPSDPTKPSITKTPVEPTKIEKDPENRATSVLKASKIPKTGDSSMIWLVFVGLGLTAIGISS
YQKKANK

Sequences:

>Translated_407_residues
MKKIIALITAVALLSMIGFAFIPGTVANAANSSESSLTYKDVRSGFYFVGYENVQLETGKTYKYTVAYEANVDMKMTDTI
TGQSAKAGLFTPKSSGAELNTSYVSRTKNNVIDVADAGNKVFKHTFEFTAKENTKADIGVFLGAGSVLPTTPETTSLWKN
VTVTNETPLVQAEAPVISAEDKTINQNESFNPLNEVTASDEKDGDITKDIHVTKNTVDTTKSGKYDVDYSVTNSSNLTTT
KSIKVTVTPAAISKNTAPVINAKDQTIKVGDVFNVLKGVTAKDNEDGDLTAKIKVTKDTVNNSKKGVYQVTYTVTDSGNL
SASLTIKVTVTQDGKLIVNPSDPTKPSITKTPVEPTKIEKDPENRATSVLKASKIPKTGDSSMIWLVFVGLGLTAIGISS
YQKKANK
>Mature_407_residues
MKKIIALITAVALLSMIGFAFIPGTVANAANSSESSLTYKDVRSGFYFVGYENVQLETGKTYKYTVAYEANVDMKMTDTI
TGQSAKAGLFTPKSSGAELNTSYVSRTKNNVIDVADAGNKVFKHTFEFTAKENTKADIGVFLGAGSVLPTTPETTSLWKN
VTVTNETPLVQAEAPVISAEDKTINQNESFNPLNEVTASDEKDGDITKDIHVTKNTVDTTKSGKYDVDYSVTNSSNLTTT
KSIKVTVTPAAISKNTAPVINAKDQTIKVGDVFNVLKGVTAKDNEDGDLTAKIKVTKDTVNNSKKGVYQVTYTVTDSGNL
SASLTIKVTVTQDGKLIVNPSDPTKPSITKTPVEPTKIEKDPENRATSVLKASKIPKTGDSSMIWLVFVGLGLTAIGISS
YQKKANK

Specific function: Promotes colloidosmotic lysis by binding to the midgut epithelial cells of hymenopteran species [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011080
- InterPro:   IPR008985
- InterPro:   IPR013320 [H]

Pfam domain/function: PF07523 Big_3 [H]

EC number: NA

Molecular weight: Translated: 43576; Mature: 43576

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIALITAVALLSMIGFAFIPGTVANAANSSESSLTYKDVRSGFYFVGYENVQLETGK
CHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEHHHHHCCEEEEEEEEEEEECCC
TYKYTVAYEANVDMKMTDTITGQSAKAGLFTPKSSGAELNTSYVSRTKNNVIDVADAGNK
EEEEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCEECHHHHHHCCCCEEEEECCCCH
VFKHTFEFTAKENTKADIGVFLGAGSVLPTTPETTSLWKNVTVTNETPLVQAEAPVISAE
HEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHEEEEECCCCCEEEECCCEEECC
DKTINQNESFNPLNEVTASDEKDGDITKDIHVTKNTVDTTKSGKYDVDYSVTNSSNLTTT
CCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCEEE
KSIKVTVTPAAISKNTAPVINAKDQTIKVGDVFNVLKGVTAKDNEDGDLTAKIKVTKDTV
EEEEEEEECHHHCCCCCCEECCCCCEEEEHHHHHHHCCCCCCCCCCCCEEEEEEEEECCC
NNSKKGVYQVTYTVTDSGNLSASLTIKVTVTQDGKLIVNPSDPTKPSITKTPVEPTKIEK
CCCCCCEEEEEEEEECCCCEEEEEEEEEEEECCCEEEECCCCCCCCCCEECCCCCCCCCC
DPENRATSVLKASKIPKTGDSSMIWLVFVGLGLTAIGISSYQKKANK
CCCHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHEECHHHHHHHCCC
>Mature Secondary Structure
MKKIIALITAVALLSMIGFAFIPGTVANAANSSESSLTYKDVRSGFYFVGYENVQLETGK
CHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEHHHHHCCEEEEEEEEEEEECCC
TYKYTVAYEANVDMKMTDTITGQSAKAGLFTPKSSGAELNTSYVSRTKNNVIDVADAGNK
EEEEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCEECHHHHHHCCCCEEEEECCCCH
VFKHTFEFTAKENTKADIGVFLGAGSVLPTTPETTSLWKNVTVTNETPLVQAEAPVISAE
HEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHEEEEECCCCCEEEECCCEEECC
DKTINQNESFNPLNEVTASDEKDGDITKDIHVTKNTVDTTKSGKYDVDYSVTNSSNLTTT
CCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCEEE
KSIKVTVTPAAISKNTAPVINAKDQTIKVGDVFNVLKGVTAKDNEDGDLTAKIKVTKDTV
EEEEEEEECHHHCCCCCCEECCCCCEEEEHHHHHHHCCCCCCCCCCCCEEEEEEEEECCC
NNSKKGVYQVTYTVTDSGNLSASLTIKVTVTQDGKLIVNPSDPTKPSITKTPVEPTKIEK
CCCCCCEEEEEEEEECCCCEEEEEEEEEEEECCCEEEECCCCCCCCCCEECCCCCCCCCC
DPENRATSVLKASKIPKTGDSSMIWLVFVGLGLTAIGISSYQKKANK
CCCHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHEECHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA