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The map label for this gene is speG [H]

Identifier: 226222648

GI number: 226222648

Start: 12257

End: 12775

Strand: Direct

Name: speG [H]

Synonym: Lm4b_00009

Alternate gene names: 226222648

Gene position: 12257-12775 (Clockwise)

Preceding gene: 226222647

Following gene: 226222649

Centisome position: 0.42

GC content: 33.72

Gene sequence:

>519_bases
ATGAGTGGAGATTTAAAACTTAGACCGCTTGAACGAGAAGATTTAAAATTTGTTCACCGGTTAAATAATGACGCGAAAAT
AATGTCTTATTGGTTTGAAGAGCCATATGAGGCGTTCGTCGAGCTTCAGGAGCTATATGATAAGCACATTCACGATCAGT
CAGAACGCCGTTTTATTTTAGAATTAGATGGCCAAATGGTTGGATTAGTTGAGTTAATGGAAATTGATTATATTCACAGA
AGAGCCGAATTTCAAATTATTATTGATCCTAAGTTTCAGGGACACGGTTACGCTGTTTCTGCCACAAAACTCGCAATGAA
ATATGCTTTTCACGTACTAAATCTGCATAAACTATATTTAGTTGTTGATAAAGTAAATGAAAAAGCTATTCATGTCTATG
AAAAAGTTGGTTTTATTCGTGAAGGCGAACTAATTGATGAGTTTTTCGTTGATGGAACTTATCATGATGCTATTAGAATG
TGTATTTTCCAACATCAATATCAAGAAATGGATATTTAA

Upstream 100 bases:

>100_bases
TTTTACGATGAAAGATATGGAAAACAAACCATTATTGACTCGTATAAAAGAAGTTCTATCTAGTTTACTATCACCAATTT
TATAATTTAGGAGTGGAAAA

Downstream 100 bases:

>100_bases
AAGGTGATTGGCGCGGGAAAAGTTGCGCCAATCATTGTTTTGGGTCAAAAAAAGTTCTATAATAAGGTTTTAGTGAAAAA
ATTATGGTATCATGAAGTAT

Product: spermidine N1-acetyltransferase

Products: NA

Alternate protein names: Diamine acetyltransferase; SAT [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSGDLKLRPLEREDLKFVHRLNNDAKIMSYWFEEPYEAFVELQELYDKHIHDQSERRFILELDGQMVGLVELMEIDYIHR
RAEFQIIIDPKFQGHGYAVSATKLAMKYAFHVLNLHKLYLVVDKVNEKAIHVYEKVGFIREGELIDEFFVDGTYHDAIRM
CIFQHQYQEMDI

Sequences:

>Translated_172_residues
MSGDLKLRPLEREDLKFVHRLNNDAKIMSYWFEEPYEAFVELQELYDKHIHDQSERRFILELDGQMVGLVELMEIDYIHR
RAEFQIIIDPKFQGHGYAVSATKLAMKYAFHVLNLHKLYLVVDKVNEKAIHVYEKVGFIREGELIDEFFVDGTYHDAIRM
CIFQHQYQEMDI
>Mature_171_residues
SGDLKLRPLEREDLKFVHRLNNDAKIMSYWFEEPYEAFVELQELYDKHIHDQSERRFILELDGQMVGLVELMEIDYIHRR
AEFQIIIDPKFQGHGYAVSATKLAMKYAFHVLNLHKLYLVVDKVNEKAIHVYEKVGFIREGELIDEFFVDGTYHDAIRMC
IFQHQYQEMDI

Specific function: Regulates polyamine concentration by their degradation. Acts on spermidine, forming N(1)- and N(8)-acetylspermidine [H]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1787867, Length=164, Percent_Identity=70.7317073170732, Blast_Score=254, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.57 [H]

Molecular weight: Translated: 20601; Mature: 20470

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDLKLRPLEREDLKFVHRLNNDAKIMSYWFEEPYEAFVELQELYDKHIHDQSERRFIL
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEE
ELDGQMVGLVELMEIDYIHRRAEFQIIIDPKFQGHGYAVSATKLAMKYAFHVLNLHKLYL
EECCCEEHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEE
VVDKVNEKAIHVYEKVGFIREGELIDEFFVDGTYHDAIRMCIFQHQYQEMDI
EEECCCCHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGDLKLRPLEREDLKFVHRLNNDAKIMSYWFEEPYEAFVELQELYDKHIHDQSERRFIL
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEE
ELDGQMVGLVELMEIDYIHRRAEFQIIIDPKFQGHGYAVSATKLAMKYAFHVLNLHKLYL
EECCCEEHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEE
VVDKVNEKAIHVYEKVGFIREGELIDEFFVDGTYHDAIRMCIFQHQYQEMDI
EEECCCCHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]