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The map label for this gene is rutG [H]

Identifier: 225686250

GI number: 225686250

Start: 410102

End: 411382

Strand: Reverse

Name: rutG [H]

Synonym: BMEA_B0421

Alternate gene names: 225686250

Gene position: 411382-410102 (Counterclockwise)

Preceding gene: 225686253

Following gene: 225686245

Centisome position: 34.7

GC content: 59.17

Gene sequence:

>1281_bases
ATGGGCTATTTTCCAAGTTGGCGTTTGACATCGAACGCCGTCGTGCTTCCTGACGAACGCCTGCCCGCAGCGGCAGCCGT
ACCAATGGGCATCCAACACCTTCTCGCCATGTCGGGCTCGACCATCGTGGCCCCCCTGCTCATGGGGTTCGATCCCAATG
TCGCCGTGTTCTTTTCAGGCATCGGAACACTCCTGTTCTTCCTCATCACCGCAGGCCGGGTGCCAAGCTATCTGGGCTCG
TCCTTTGCCTTCATCGCGGTCGTCATCGCCGCGACGGGCTATAGCGGCAGCGGCCCCAATCCCAATATCGCCATCGCGCT
TGGCGGTATCATCGCCTGCGGCGCGCTCTATTCGCTGATCGGCCTCATCGTCATGTTCCTCGGCACAGGCTGGGTGGAAA
AACTGATGCCGCCTGCCGTCACCGGCGCAATCGGCGTTTCCATCGGCCTCAATCTTGCCCCGGTCGCCATCGGCCAGTTG
AAGGGCACGGGCGCTCACACCAGTATCGCGCTTCTTACCGTGCTGTGCATGGCAATGATTTCCGCCTACGGACCGCGCGG
AACCCGGCGCCTTTCGGTGCTGTTCGCACTGCTTTTCGGCTATCTGCTCGTTCTGATCGCCGGAAACGGCCTGGGCATCG
TTCCCGGCATTGATTTCACAGCCGTCAAAAACGCCGCATGGTTCGGCCTGCCGCATTTCACGACACCGGCATTCAACTGG
CAGGCAGTCACGCTGATTGCTCCGGTCGCCATTGTTCTCGTTGCGGAAAACCTCGGCCACATCAAGGCTCTCGGCTCCAT
TACCGGACGCAACATGGACGGCTATATCGGCCGCGGCTTCTTCAGCGATGGCCTTGCCACCATGATTTCAGGCGCAGGCG
GCGGCACGGGCGTCACCACCTATGCGGAAAATATCGGCGTCATGGCCATGACCAAGGTTTATTCGACGCTGATCTTTGTT
ATTGCCGCCATCATGGCTCTCATTCTTGGCATGTCGCCCAAGTTCGGCGCGATCCTGCAAACCATTCCCGCCCCTGTTCT
TGCTGGTCTTGCGGTGTCAGTGTTCGGCCTTATCGCCTCGGCCATGGCGCGCATCTGGATCGTCAACAAGGTTGATTTTG
CAGATTCCCGCAATCTCTTCACTGTCGGCGTGGCGCTCATCTTCGGTGCAGGCGATTTCACCTTGAACATTGGCAATTTC
GCACTCGGCGGCATCGCCACCTCCACGCTGGCCGCGCTTGTTCTCTATCAGCTTTTGGGAATTGGCCGTTCTGATAGTTA
A

Upstream 100 bases:

>100_bases
AGCTTTCACTAGAAATAGTCTGAAGAATCCTGATCCCTCTGGAAATCACGAACGCGAGGCGATAAAGCCAAGGGGGAACT
ACATCTTCCAGAGGGACATC

Downstream 100 bases:

>100_bases
AAAAGCAGGCCGGAGCGACGTTGTTTCATCAACTGCTCCGGCCCGTCCTCCGGCTGCACGATTACGAGGGGTAATTGCAG
CACCGTGCCGATTTTTATGG

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MGYFPSWRLTSNAVVLPDERLPAAAAVPMGIQHLLAMSGSTIVAPLLMGFDPNVAVFFSGIGTLLFFLITAGRVPSYLGS
SFAFIAVVIAATGYSGSGPNPNIAIALGGIIACGALYSLIGLIVMFLGTGWVEKLMPPAVTGAIGVSIGLNLAPVAIGQL
KGTGAHTSIALLTVLCMAMISAYGPRGTRRLSVLFALLFGYLLVLIAGNGLGIVPGIDFTAVKNAAWFGLPHFTTPAFNW
QAVTLIAPVAIVLVAENLGHIKALGSITGRNMDGYIGRGFFSDGLATMISGAGGGTGVTTYAENIGVMAMTKVYSTLIFV
IAAIMALILGMSPKFGAILQTIPAPVLAGLAVSVFGLIASAMARIWIVNKVDFADSRNLFTVGVALIFGAGDFTLNIGNF
ALGGIATSTLAALVLYQLLGIGRSDS

Sequences:

>Translated_426_residues
MGYFPSWRLTSNAVVLPDERLPAAAAVPMGIQHLLAMSGSTIVAPLLMGFDPNVAVFFSGIGTLLFFLITAGRVPSYLGS
SFAFIAVVIAATGYSGSGPNPNIAIALGGIIACGALYSLIGLIVMFLGTGWVEKLMPPAVTGAIGVSIGLNLAPVAIGQL
KGTGAHTSIALLTVLCMAMISAYGPRGTRRLSVLFALLFGYLLVLIAGNGLGIVPGIDFTAVKNAAWFGLPHFTTPAFNW
QAVTLIAPVAIVLVAENLGHIKALGSITGRNMDGYIGRGFFSDGLATMISGAGGGTGVTTYAENIGVMAMTKVYSTLIFV
IAAIMALILGMSPKFGAILQTIPAPVLAGLAVSVFGLIASAMARIWIVNKVDFADSRNLFTVGVALIFGAGDFTLNIGNF
ALGGIATSTLAALVLYQLLGIGRSDS
>Mature_425_residues
GYFPSWRLTSNAVVLPDERLPAAAAVPMGIQHLLAMSGSTIVAPLLMGFDPNVAVFFSGIGTLLFFLITAGRVPSYLGSS
FAFIAVVIAATGYSGSGPNPNIAIALGGIIACGALYSLIGLIVMFLGTGWVEKLMPPAVTGAIGVSIGLNLAPVAIGQLK
GTGAHTSIALLTVLCMAMISAYGPRGTRRLSVLFALLFGYLLVLIAGNGLGIVPGIDFTAVKNAAWFGLPHFTTPAFNWQ
AVTLIAPVAIVLVAENLGHIKALGSITGRNMDGYIGRGFFSDGLATMISGAGGGTGVTTYAENIGVMAMTKVYSTLIFVI
AAIMALILGMSPKFGAILQTIPAPVLAGLAVSVFGLIASAMARIWIVNKVDFADSRNLFTVGVALIFGAGDFTLNIGNFA
LGGIATSTLAALVLYQLLGIGRSDS

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=176, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI40316845, Length=176, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI44680143, Length=116, Percent_Identity=37.9310344827586, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI44680145, Length=116, Percent_Identity=37.9310344827586, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI87081818, Length=420, Percent_Identity=58.8095238095238, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI1788843, Length=424, Percent_Identity=38.2075471698113, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI87082181, Length=399, Percent_Identity=26.0651629072682, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI87082178, Length=384, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790087, Length=407, Percent_Identity=23.5872235872236, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17558856, Length=190, Percent_Identity=32.1052631578947, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17541904, Length=174, Percent_Identity=33.9080459770115, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17542262, Length=193, Percent_Identity=31.6062176165803, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17542260, Length=189, Percent_Identity=29.1005291005291, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993493, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356175, Length=181, Percent_Identity=28.1767955801105, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 43679; Mature: 43548

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYFPSWRLTSNAVVLPDERLPAAAAVPMGIQHLLAMSGSTIVAPLLMGFDPNVAVFFSG
CCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
IGTLLFFLITAGRVPSYLGSSFAFIAVVIAATGYSGSGPNPNIAIALGGIIACGALYSLI
HHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
GLIVMFLGTGWVEKLMPPAVTGAIGVSIGLNLAPVAIGQLKGTGAHTSIALLTVLCMAMI
HHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SAYGPRGTRRLSVLFALLFGYLLVLIAGNGLGIVPGIDFTAVKNAAWFGLPHFTTPAFNW
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCEECCCCCCCCCCCC
QAVTLIAPVAIVLVAENLGHIKALGSITGRNMDGYIGRGFFSDGLATMISGAGGGTGVTT
CHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCHHH
YAENIGVMAMTKVYSTLIFVIAAIMALILGMSPKFGAILQTIPAPVLAGLAVSVFGLIAS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMARIWIVNKVDFADSRNLFTVGVALIFGAGDFTLNIGNFALGGIATSTLAALVLYQLLG
HHHHHHEEEEECCCCCCCHHHEEHHHHEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHC
IGRSDS
CCCCCC
>Mature Secondary Structure 
GYFPSWRLTSNAVVLPDERLPAAAAVPMGIQHLLAMSGSTIVAPLLMGFDPNVAVFFSG
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
IGTLLFFLITAGRVPSYLGSSFAFIAVVIAATGYSGSGPNPNIAIALGGIIACGALYSLI
HHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
GLIVMFLGTGWVEKLMPPAVTGAIGVSIGLNLAPVAIGQLKGTGAHTSIALLTVLCMAMI
HHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SAYGPRGTRRLSVLFALLFGYLLVLIAGNGLGIVPGIDFTAVKNAAWFGLPHFTTPAFNW
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCEECCCCCCCCCCCC
QAVTLIAPVAIVLVAENLGHIKALGSITGRNMDGYIGRGFFSDGLATMISGAGGGTGVTT
CHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCHHH
YAENIGVMAMTKVYSTLIFVIAAIMALILGMSPKFGAILQTIPAPVLAGLAVSVFGLIAS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMARIWIVNKVDFADSRNLFTVGVALIFGAGDFTLNIGNFALGGIATSTLAALVLYQLLG
HHHHHHEEEEECCCCCCCHHHEEHHHHEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHC
IGRSDS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]