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The map label for this gene is rfbC [C]

Identifier: 225686245

GI number: 225686245

Start: 406296

End: 406787

Strand: Reverse

Name: rfbC [C]

Synonym: BMEA_B0416

Alternate gene names: 225686245

Gene position: 406787-406296 (Counterclockwise)

Preceding gene: 225686250

Following gene: 225686240

Centisome position: 34.31

GC content: 59.35

Gene sequence:

>492_bases
ATGGTCCATCGAGCCGGAACGGCGAAGGACGAGCGCGGCTGGTTCGCGCGGGTCTATTGCGAGGCGGCCTTTGCCGAACG
GAAGCTGGAAACACACTTTCCCCAGCACAGCCTTTCCTTCTCGCGCGAGAAGGGAACCCTGCGCGGACTGCATTATCAGA
ACGAGCCGCATAGCGAGACGAAACTCGTCACCTGCCTGCAAGGCATCGTCTGGGATGTGCTGGTGGATCTTCGCCCCCAT
TCACCCACTTATCGGCGGTGGGCGGGGGTGGAACTTTCAGCCGAAAACGGTGTGCAACTCTATATACCGGAAGGCTGCGC
CCACGGTTTCCAGACGCTGACGGATGATGTCCTCATCCGCTACATGATCTCGAAGCCCTATGCGCCCGATCATGCCGCCG
GCATCCGCTATGACGATCCAGCCCTCGACATTCCATGGCCGGAGAAGCCCAGCGTCATTTCGCAAAAAGATCTTGGCTGG
CCGTTTCTTTGA

Upstream 100 bases:

>100_bases
AAAGAAAGTTCTATCGCCGTAAGGACAGGCTGGCAGAATGCAAAAATGCAGCAATCGGGGGCAGGCTCATGCATTTCACT
CCGCTCAACAGCAACGGCGC

Downstream 100 bases:

>100_bases
TCAATCCCGCATCGCGAAGCCGGTCGGCCGCATCGGCAAGCATGGCGAAGGGCAGTTTCGACCGCTCCGCCATGTCGAGA
ATCGAATAGCCGCCATCGGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MVHRAGTAKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSETKLVTCLQGIVWDVLVDLRPH
SPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEKPSVISQKDLGW
PFL

Sequences:

>Translated_163_residues
MVHRAGTAKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSETKLVTCLQGIVWDVLVDLRPH
SPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEKPSVISQKDLGW
PFL
>Mature_163_residues
MVHRAGTAKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSETKLVTCLQGIVWDVLVDLRPH
SPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEKPSVISQKDLGW
PFL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=150, Percent_Identity=38, Blast_Score=110, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17550412, Length=153, Percent_Identity=39.2156862745098, Blast_Score=92, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 18617; Mature: 18617

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHRAGTAKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSET
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCHH
KLVTCLQGIVWDVLVDLRPHSPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIR
HHHHHHHHHHHHHHHHCCCCCCCCCEECCEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
YMISKPYAPDHAAGIRYDDPALDIPWPEKPSVISQKDLGWPFL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVHRAGTAKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSET
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCHH
KLVTCLQGIVWDVLVDLRPHSPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIR
HHHHHHHHHHHHHHHHCCCCCCCCCEECCEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
YMISKPYAPDHAAGIRYDDPALDIPWPEKPSVISQKDLGWPFL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]