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The map label for this gene is mmgC [H]

Identifier: 225686253

GI number: 225686253

Start: 415924

End: 417066

Strand: Reverse

Name: mmgC [H]

Synonym: BMEA_B0426

Alternate gene names: 225686253

Gene position: 417066-415924 (Counterclockwise)

Preceding gene: 225686254

Following gene: 225686250

Centisome position: 35.18

GC content: 61.42

Gene sequence:

>1143_bases
ATGCTTCTGACCGATACGCAGGAACAGATCCGCGAAGCCGCCCGCGACTTCGCACAGGAGCGCCTTGCCCCCGGCGCCGC
GGCGCGTGACCGTGAACATGCATTTCCCCGCGCCGAACTGACTGAAATGGGCGCGCTTGGCTTTCTCGGAATGCTGGTGC
CGGAAGAATGGGGCGGCTCCGACCTCGGCATGGTTGCCTATGCTCTGGCGCTGGAAGAGATAGCGGCAGGCGACGGTGCC
TGCTCGACCATCGTATCGGTGCATTCCTCCGTCGGCTGTATGCCGATCTTACGTTTCGGCACGGAAGACCAGAAGCGCCG
CTTCCTGCCCAAAATGGCCTGTGGCGAATGGATCGGCGGCTTTGCCCTCACCGAGCCGCAGGCCGGTTCCGATGCCTCCG
CGCTGAAAACGCGCGCCCGGCTCGACGGCGATCATTATGTGATCGACGGTTCCAAGCAGTTCATCACATCAGGCAAGAAC
GGCAATGTCGTGATCGTTTTTGCCGTTACCGATCCTGCCGCAGGCAAGAAGGGTATTTCCGCCTTCATCGTGCCCACCGA
TACGCCAGGTTATGAGGTGATGTCGGTCGAACACAAGCTCGGCCAGCATTCATCCGACACCTGTGCGCTCGGCTTCACCA
ATATGCGCGTTCCGGTCGAAAACCGGCTGGGCGCTGAAGGCGAAGGCTACAAGATCGCCCTTGCCAATCTGGAAGGCGGA
CGCATCGGCATCGCAGCCCAGGCGGTTGGCATGGCGCGCGCCGCTTTCGAGGCGGCACGCGATTATGCCCGCGAACGCAT
TACCTTCGGCAAGCCGATCATCGAACATCAGGCCGTGGCCTTCCGCCTTGCCGACATGGCAACCCGGATCGAAACCGCCC
GGCAGATGGTGTTACACGCCGCTGCCCTGCGCGAAGCAGGCAAGCCATGCCTTACCGAAGCTTCAATGGCAAAGCTGGTC
GCATCGGAAATGGCCGAACAGGTCTGTTCCGCAGCCATCCAGATTCATGGCGGCTATGGCTATCTGGCCGATTATCGGTC
GAGCGCATCTATCGCGAGGTCCGCGTCTGCCAGATTTATGAAGGCACAAGCGACGTGCAGCGGCTCGTCATCGCGCGCGG
GCTATAATCAGCCTTCGACCTGA

Upstream 100 bases:

>100_bases
TGCTGGCGGCACTTGAAACACATGGCCTGAAGCGCGGCATCGCGGGCATCTGCCTTGGCGGCGGCGAGGCAACCGCAATG
GGTATCGAAAGGATCATCTG

Downstream 100 bases:

>100_bases
TCGAGATAATCGCCATAACCTTCCGCTTCCATCCGGTCTTTCGGCACAAAACGGAGGGAAGCGGAGTTGATGCAATAGCG
CAAGCCGCCACGATCCACCG

Product: acyl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLVPEEWGGSDLGMVAYALALEEIAAGDGA
CSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKN
GNVVIVFAVTDPAAGKKGISAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGG
RIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAAALREAGKPCLTEASMAKLV
ASEMAEQVCSAAIQIHGGYGYLADYRSSASIARSASARFMKAQATCSGSSSRAGYNQPST

Sequences:

>Translated_380_residues
MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLVPEEWGGSDLGMVAYALALEEIAAGDGA
CSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKN
GNVVIVFAVTDPAAGKKGISAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGG
RIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAAALREAGKPCLTEASMAKLV
ASEMAEQVCSAAIQIHGGYGYLADYRSSASIARSASARFMKAQATCSGSSSRAGYNQPST
>Mature_380_residues
MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLVPEEWGGSDLGMVAYALALEEIAAGDGA
CSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKN
GNVVIVFAVTDPAAGKKGISAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGG
RIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAAALREAGKPCLTEASMAKLV
ASEMAEQVCSAAIQIHGGYGYLADYRSSASIARSASARFMKAQATCSGSSSRAGYNQPST

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=342, Percent_Identity=45.906432748538, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI4501859, Length=343, Percent_Identity=40.8163265306122, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI7656849, Length=346, Percent_Identity=39.5953757225434, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI187960098, Length=346, Percent_Identity=37.5722543352601, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4557231, Length=346, Percent_Identity=37.5722543352601, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI226958412, Length=347, Percent_Identity=36.3112391930836, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI21361497, Length=324, Percent_Identity=38.8888888888889, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI226958414, Length=306, Percent_Identity=36.2745098039216, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4501857, Length=347, Percent_Identity=34.0057636887608, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI4557235, Length=307, Percent_Identity=36.8078175895765, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI76496475, Length=307, Percent_Identity=36.8078175895765, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI4503943, Length=346, Percent_Identity=30.9248554913295, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7669494, Length=346, Percent_Identity=30.9248554913295, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI211971008, Length=319, Percent_Identity=32.2884012539185, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI48976061, Length=319, Percent_Identity=32.2884012539185, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI38505218, Length=321, Percent_Identity=30.5295950155763, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI218563752, Length=223, Percent_Identity=27.8026905829596, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=351, Percent_Identity=34.4729344729345, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786223, Length=348, Percent_Identity=30.1724137931034, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI87081702, Length=317, Percent_Identity=26.4984227129338, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87082384, Length=234, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=346, Percent_Identity=36.4161849710983, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17538396, Length=345, Percent_Identity=34.4927536231884, Blast_Score=228, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17508101, Length=343, Percent_Identity=37.0262390670554, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17534899, Length=350, Percent_Identity=38.5714285714286, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=43.4782608695652, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17570075, Length=348, Percent_Identity=36.7816091954023, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17569725, Length=348, Percent_Identity=36.4942528735632, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17533517, Length=340, Percent_Identity=35.2941176470588, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI71985184, Length=321, Percent_Identity=37.3831775700935, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=40.2597402597403, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=298, Percent_Identity=35.9060402684564, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17534353, Length=346, Percent_Identity=31.7919075144509, Blast_Score=170, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=31.8681318681319, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17551932, Length=331, Percent_Identity=32.3262839879154, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17505929, Length=348, Percent_Identity=29.0229885057471, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17562446, Length=297, Percent_Identity=30.6397306397306, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17531909, Length=211, Percent_Identity=30.8056872037915, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI86563383, Length=295, Percent_Identity=27.7966101694915, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=295, Percent_Identity=27.7966101694915, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356377, Length=342, Percent_Identity=45.0292397660819, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24646207, Length=342, Percent_Identity=43.5672514619883, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24666513, Length=344, Percent_Identity=41.5697674418605, Blast_Score=261, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24660351, Length=348, Percent_Identity=38.5057471264368, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI21355753, Length=357, Percent_Identity=35.5742296918768, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI281363737, Length=327, Percent_Identity=35.474006116208, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19920834, Length=307, Percent_Identity=35.1791530944625, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 40319; Mature: 40319

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLVPEEWGGS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
DLGMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGG
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHEECCCCHHHHHHCHHHHHHHHHCC
FALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGIS
EEECCCCCCCCHHHHHHHHHCCCCEEEECCCHHEEECCCCCCEEEEEEECCCCCCCCCCE
AFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGG
EEEEECCCCCCEEEEEHHHHCCCCCCCEEEECCCEECCHHHCCCCCCCCEEEEEEECCCC
RIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYRSSASIARSASARFM
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHCCHHHHHHHHHHHHH
KAQATCSGSSSRAGYNQPST
HHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLVPEEWGGS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
DLGMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGG
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHEECCCCHHHHHHCHHHHHHHHHCC
FALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGIS
EEECCCCCCCCHHHHHHHHHCCCCEEEECCCHHEEECCCCCCEEEEEEECCCCCCCCCCE
AFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGG
EEEEECCCCCCEEEEEHHHHCCCCCCCEEEECCCEECCHHHCCCCCCCCEEEEEEECCCC
RIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYRSSASIARSASARFM
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHCCHHHHHHHHHHHHH
KAQATCSGSSSRAGYNQPST
HHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]