Click here to switch to the map view.

The map label for this gene is entC [H]

Identifier: 225685884

GI number: 225685884

Start: 13824

End: 14999

Strand: Reverse

Name: entC [H]

Synonym: BMEA_B0018

Alternate gene names: 225685884

Gene position: 14999-13824 (Counterclockwise)

Preceding gene: 225685886

Following gene: 225685883

Centisome position: 1.27

GC content: 61.56

Gene sequence:

>1176_bases
GTGAGAACGAGCGCCCTGAAATACCCAACTTCAGACGCAGACCATCTTATTGAAAATAATACTGATTTCTCGTTTGCATC
CGGCAATCTGAAACTGGCGGCCAGCGGCATGCGTGAGGTGATCGCGACGCCTGCCATTGGCGGCAGCAACCCCGACAGCA
CCTTCCAGCGGGCAATTGCGCAGGCTTTCGAGCGCGCCGCACGCGCTGGGCAGCGCAATCCGATCGTGGTGGGTGCAATC
CCGTTCGACCCCGGCGAACCCTCCTGTCTCTATGTGCCCGAGGAGATGGACTGGCAGGAGCGGGAGCCAGCCAGCGGGGC
GAGCGCCGCCGCCATGCCGCAACTGGCGGGGCAGAGAAGCGTACCGGACGAAGCGGGTTTCAAGCACGCGGTAGAACATG
CCATCATCAATTTTCGCCTTAGCGACGTGCGCAAGGCGGTGCTTTCGGTGATGCGCGAACTCACTTTCGCGGACGATATC
GATGTCGACGCCATACTGGCCAATCTGCGCGCGCAAAACCATGACGGCTATCAGTTTCGCGTGCCTTTGCCCGGTGGCGG
CGCATTGGTCGGTGTCAGCCCGGAACTCCTGATCCACAAGGACAAGGGAAAGATCGTATCCAACCCTCTGGCCGGATCGG
CGAAGCGCATGGCCGACCCGGAGGCGGACAGGAAAAATGCCGATCGCCTGGCCAAATCCGAAAAGGACCATTACGAACAT
CGCCTGGTGATCGAGGATATCAGAGCACGGCTTCAGCCCATCTGCACGGAACTGGACATACCGGAACGGCCGTCGCTCAT
CCACACGGCAGCACTCTGGCATCTTTCGACCCGCATCGAGGGCCGGCTGCATGATCCCGATATGACAGCCTTGCAGCTTG
CCTGCCTCATCCACCCGACGCCTGCCGTCTGCGGTTTCCCGACCGAGCGCGCGCGCCGCCTGATCCGCTTTGTAGAACCT
TTCGAGCGTGGATTGTTTACCGGCATGGTCGGCTGGAGCGACGCGGAAGGCAATGGCGAATGGGTCGTCACCATCCGTTG
CGGCACGGTGAAGGGCAATCTTGTGCGCCTCTTTGCCGGGGCGGGGATCGTGGAAGCCTCCAGCCCGGATTCCGAATGGG
CCGAAGTACAGACCAAGCTTGGCACCATGCTGCGTGCCTGCGGCCTTTCGGCCTGA

Upstream 100 bases:

>100_bases
CAATCACCCGGTTGACAAATTGGGACCAATTAAATCAAGTATAAAACGTGACTGGTTCTTTCAAGTATTAATTTCGGCAA
CGACGCCAAGGAGACTCCCC

Downstream 100 bases:

>100_bases
AACAGAGCCTCTCCATGTCTTTGTTTCTACGCATTATCCGACGCAGAGCCGCTTCGCATTGCGGGCTCGAAAACTGCACT
CGTTTTTATTTCAAGCAGAA

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRTSALKYPTSDADHLIENNTDFSFASGNLKLAASGMREVIATPAIGGSNPDSTFQRAIAQAFERAARAGQRNPIVVGAI
PFDPGEPSCLYVPEEMDWQEREPASGASAAAMPQLAGQRSVPDEAGFKHAVEHAIINFRLSDVRKAVLSVMRELTFADDI
DVDAILANLRAQNHDGYQFRVPLPGGGALVGVSPELLIHKDKGKIVSNPLAGSAKRMADPEADRKNADRLAKSEKDHYEH
RLVIEDIRARLQPICTELDIPERPSLIHTAALWHLSTRIEGRLHDPDMTALQLACLIHPTPAVCGFPTERARRLIRFVEP
FERGLFTGMVGWSDAEGNGEWVVTIRCGTVKGNLVRLFAGAGIVEASSPDSEWAEVQTKLGTMLRACGLSA

Sequences:

>Translated_391_residues
MRTSALKYPTSDADHLIENNTDFSFASGNLKLAASGMREVIATPAIGGSNPDSTFQRAIAQAFERAARAGQRNPIVVGAI
PFDPGEPSCLYVPEEMDWQEREPASGASAAAMPQLAGQRSVPDEAGFKHAVEHAIINFRLSDVRKAVLSVMRELTFADDI
DVDAILANLRAQNHDGYQFRVPLPGGGALVGVSPELLIHKDKGKIVSNPLAGSAKRMADPEADRKNADRLAKSEKDHYEH
RLVIEDIRARLQPICTELDIPERPSLIHTAALWHLSTRIEGRLHDPDMTALQLACLIHPTPAVCGFPTERARRLIRFVEP
FERGLFTGMVGWSDAEGNGEWVVTIRCGTVKGNLVRLFAGAGIVEASSPDSEWAEVQTKLGTMLRACGLSA
>Mature_391_residues
MRTSALKYPTSDADHLIENNTDFSFASGNLKLAASGMREVIATPAIGGSNPDSTFQRAIAQAFERAARAGQRNPIVVGAI
PFDPGEPSCLYVPEEMDWQEREPASGASAAAMPQLAGQRSVPDEAGFKHAVEHAIINFRLSDVRKAVLSVMRELTFADDI
DVDAILANLRAQNHDGYQFRVPLPGGGALVGVSPELLIHKDKGKIVSNPLAGSAKRMADPEADRKNADRLAKSEKDHYEH
RLVIEDIRARLQPICTELDIPERPSLIHTAALWHLSTRIEGRLHDPDMTALQLACLIHPTPAVCGFPTERARRLIRFVEP
FERGLFTGMVGWSDAEGNGEWVVTIRCGTVKGNLVRLFAGAGIVEASSPDSEWAEVQTKLGTMLRACGLSA

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=373, Percent_Identity=45.8445040214477, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI87082077, Length=269, Percent_Identity=32.3420074349442, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788114, Length=201, Percent_Identity=29.3532338308458, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787518, Length=229, Percent_Identity=30.5676855895196, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=220, Percent_Identity=31.3636363636364, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 42497; Mature: 42497

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSALKYPTSDADHLIENNTDFSFASGNLKLAASGMREVIATPAIGGSNPDSTFQRAIA
CCCCCCCCCCCCHHHHHCCCCCCEEECCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHH
QAFERAARAGQRNPIVVGAIPFDPGEPSCLYVPEEMDWQEREPASGASAAAMPQLAGQRS
HHHHHHHHCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCC
VPDEAGFKHAVEHAIINFRLSDVRKAVLSVMRELTFADDIDVDAILANLRAQNHDGYQFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEE
VPLPGGGALVGVSPELLIHKDKGKIVSNPLAGSAKRMADPEADRKNADRLAKSEKDHYEH
EECCCCCEEEECCCEEEEECCCCCEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
RLVIEDIRARLQPICTELDIPERPSLIHTAALWHLSTRIEGRLHDPDMTALQLACLIHPT
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCC
PAVCGFPTERARRLIRFVEPFERGLFTGMVGWSDAEGNGEWVVTIRCGTVKGNLVRLFAG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEC
AGIVEASSPDSEWAEVQTKLGTMLRACGLSA
CCEEECCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTSALKYPTSDADHLIENNTDFSFASGNLKLAASGMREVIATPAIGGSNPDSTFQRAIA
CCCCCCCCCCCCHHHHHCCCCCCEEECCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHH
QAFERAARAGQRNPIVVGAIPFDPGEPSCLYVPEEMDWQEREPASGASAAAMPQLAGQRS
HHHHHHHHCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCC
VPDEAGFKHAVEHAIINFRLSDVRKAVLSVMRELTFADDIDVDAILANLRAQNHDGYQFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEE
VPLPGGGALVGVSPELLIHKDKGKIVSNPLAGSAKRMADPEADRKNADRLAKSEKDHYEH
EECCCCCEEEECCCEEEEECCCCCEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
RLVIEDIRARLQPICTELDIPERPSLIHTAALWHLSTRIEGRLHDPDMTALQLACLIHPT
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCC
PAVCGFPTERARRLIRFVEPFERGLFTGMVGWSDAEGNGEWVVTIRCGTVKGNLVRLFAG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEC
AGIVEASSPDSEWAEVQTKLGTMLRACGLSA
CCEEECCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]