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The map label for this gene is pgsA [H]

Identifier: 225630081

GI number: 225630081

Start: 270856

End: 271398

Strand: Direct

Name: pgsA [H]

Synonym: WRi_002580

Alternate gene names: 225630081

Gene position: 270856-271398 (Clockwise)

Preceding gene: 225630077

Following gene: 225630083

Centisome position: 18.73

GC content: 34.25

Gene sequence:

>543_bases
ATGCTTAAGAAAAACGTGCCTAATTTGCTTACAATTTCTCGTGCGCTTGCAGTACCAGCAATAATATTAAGTTTTTATAT
AGAAAATAAATATGCAGGCCTGATAACAATATCAATCTTTGTGTTTGCGTGCATTACGGATTTTTTTGATGGTTACTTGG
CGCGTGCGTGGAAAGTCCAATCAAAATTTGGCAAGCTATTTGATCCAATTGCTGATAAATTAATAGTGGTTTCAACGATA
ATTATGCTAGTTTATAAGCAGAAGATAAATGATTTTACAATAGTACCATCGATTATCATCATCTGTAGGGAGATATTAGT
CTCGGGTTTGCGGGAGTTTTTGATAGCTACAAATGTTAGTCTACCTGTAAGCAAAGCTGGAAAAATTAAAACATTTTTGC
AGATGGTTGCTGTAGTAGCGCTAATAATGAACGATTATTATATGATTCAATATACAGGTGCGATTTGTTTATGGGTTGCA
GCTATTATAACTATGTGGTCAGGCTATAATTATATCCTAGCCGGCATCAAACAGATTGATTAA

Upstream 100 bases:

>100_bases
AAGTATATGGAGTTTTTATAAATGTTCAATTGTAAACTATTAGCTTGTGAACTCTGGTGTACTTCTGTATAAGTTTACCT
ACTACGTAGAATGGTATTAC

Downstream 100 bases:

>100_bases
ATCTCCTAGGAAATAGTTAATAGACAAGAGTAGTTAATATCTTAGTGATATTGACTCAGAAAGCAAAAAGGTGTATAATT
GTATTAACTTACAACTAATT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MLKKNVPNLLTISRALAVPAIILSFYIENKYAGLITISIFVFACITDFFDGYLARAWKVQSKFGKLFDPIADKLIVVSTI
IMLVYKQKINDFTIVPSIIIICREILVSGLREFLIATNVSLPVSKAGKIKTFLQMVAVVALIMNDYYMIQYTGAICLWVA
AIITMWSGYNYILAGIKQID

Sequences:

>Translated_180_residues
MLKKNVPNLLTISRALAVPAIILSFYIENKYAGLITISIFVFACITDFFDGYLARAWKVQSKFGKLFDPIADKLIVVSTI
IMLVYKQKINDFTIVPSIIIICREILVSGLREFLIATNVSLPVSKAGKIKTFLQMVAVVALIMNDYYMIQYTGAICLWVA
AIITMWSGYNYILAGIKQID
>Mature_180_residues
MLKKNVPNLLTISRALAVPAIILSFYIENKYAGLITISIFVFACITDFFDGYLARAWKVQSKFGKLFDPIADKLIVVSTI
IMLVYKQKINDFTIVPSIIIICREILVSGLREFLIATNVSLPVSKAGKIKTFLQMVAVVALIMNDYYMIQYTGAICLWVA
AIITMWSGYNYILAGIKQID

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=176, Percent_Identity=35.7954545454545, Blast_Score=122, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320059, Length=104, Percent_Identity=35.5769230769231, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650130, Length=81, Percent_Identity=45.679012345679, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650126, Length=81, Percent_Identity=45.679012345679, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650128, Length=81, Percent_Identity=45.679012345679, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20203; Mature: 20203

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKNVPNLLTISRALAVPAIILSFYIENKYAGLITISIFVFACITDFFDGYLARAWKVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKFGKLFDPIADKLIVVSTIIMLVYKQKINDFTIVPSIIIICREILVSGLREFLIATNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPVSKAGKIKTFLQMVAVVALIMNDYYMIQYTGAICLWVAAIITMWSGYNYILAGIKQID
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MLKKNVPNLLTISRALAVPAIILSFYIENKYAGLITISIFVFACITDFFDGYLARAWKVQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKFGKLFDPIADKLIVVSTIIMLVYKQKINDFTIVPSIIIICREILVSGLREFLIATNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPVSKAGKIKTFLQMVAVVALIMNDYYMIQYTGAICLWVAAIITMWSGYNYILAGIKQID
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA