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The map label for this gene is obgE [H]

Identifier: 225630077

GI number: 225630077

Start: 264238

End: 265260

Strand: Direct

Name: obgE [H]

Synonym: WRi_002520

Alternate gene names: 225630077

Gene position: 264238-265260 (Clockwise)

Preceding gene: 225630076

Following gene: 225630081

Centisome position: 18.28

GC content: 36.17

Gene sequence:

>1023_bases
ATGGGTTTTATAGACGAAGTAAAATTGTGTTTAAAAGCCGGTGACGGTGGTGATGGCTGTGCAAGTTTTCGTCGAGAAAA
GTTCGTTGAATTTGGTGGTCCAAATGGTGGTAATGGAGGAAAGGGTGGAAACATAGTTTTCATCAGCGACGCTAATCTCA
ACACTTTGCTTCATTTTCGTTATAGAAGACACATTAAAGCAGATAGTGGAAAAAATGGTGCAGGCAGGGATAGATCTGGC
ACAGCAGGGAAAGACGTTATACTTAAAGTTCCAGTTGGTGCACAAATAATTGATGAAGAAAGTGAAGAGATAATAGTAGA
CCTTGACAAGCCTGGTATGGAATTTCAAGTAGCACAGGGTGGAAAAGGTGGACTTGGAAATACTAATTTTAAATCTTCTA
CTAATAAGGCACCAAGACATTTTACTTACGGTCAGCCTGGCGAAGAAAAACATGTATTATTAAAACTAAAAGTTTTATCA
GATGTTGGAATTATTGGCATGCCAAACGCAGGTAAATCAAAATTTTTGACTCGCTGCTCAAATTCCGATACAAAAGTAGG
CGATTATCCATTTACCACCGTAAGACCTCATTTAGGCATGGTAAAAGTGGATGATAGCGAAGTTGTAATAGCAGATATTC
CTGGAATAATTACTGATGCTCACCTTGGAGTTGGGCTCGGGCATAAATTTTTAAAGCACATAGAAAGGTGTCAAATTTTA
CTTCATTTAATCGATGTAACTCACGATGACGTTGTTTCGGCTTATAGTTGTATCCATAATGAATTGGAACTTTACAATAG
TGATCTTGTTGAAAAAGAAGAGATTGTAGTATTAAACAAATGCGACTTATTGAGGGAAGCAGAAATTCTGGAAAAGAAGA
ATCACCTAGCTAATTATCTCAATAAAGAAGTGCTGTGCTTATCAATTAATGGTGATTTACAGCCTATTTTAAGATTATTA
AGTGAAAAATTGAAAAAGAGTAATTCTAAGGAAATCGATGTATATGATCCTTTTAAAGCGTAA

Upstream 100 bases:

>100_bases
CCGGGTCGCTATCGCGTTCTGATAGACTCGCGAAGTATAATGAGCTAATGAGAATAGAAAGCACGTTAGGAAAGGATGCT
AAATATTATCGTGGGTTAGC

Downstream 100 bases:

>100_bases
ATTTTCTATTTATGGATGTACAAGAATGGTAGCGTGCAACCAGAACTAAGCGTACAGCTGTGCAAACATCGTGATTTGAG
TCCACCAGAAGGGTGTCATC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGFIDEVKLCLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGNIVFISDANLNTLLHFRYRRHIKADSGKNGAGRDRSG
TAGKDVILKVPVGAQIIDEESEEIIVDLDKPGMEFQVAQGGKGGLGNTNFKSSTNKAPRHFTYGQPGEEKHVLLKLKVLS
DVGIIGMPNAGKSKFLTRCSNSDTKVGDYPFTTVRPHLGMVKVDDSEVVIADIPGIITDAHLGVGLGHKFLKHIERCQIL
LHLIDVTHDDVVSAYSCIHNELELYNSDLVEKEEIVVLNKCDLLREAEILEKKNHLANYLNKEVLCLSINGDLQPILRLL
SEKLKKSNSKEIDVYDPFKA

Sequences:

>Translated_340_residues
MGFIDEVKLCLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGNIVFISDANLNTLLHFRYRRHIKADSGKNGAGRDRSG
TAGKDVILKVPVGAQIIDEESEEIIVDLDKPGMEFQVAQGGKGGLGNTNFKSSTNKAPRHFTYGQPGEEKHVLLKLKVLS
DVGIIGMPNAGKSKFLTRCSNSDTKVGDYPFTTVRPHLGMVKVDDSEVVIADIPGIITDAHLGVGLGHKFLKHIERCQIL
LHLIDVTHDDVVSAYSCIHNELELYNSDLVEKEEIVVLNKCDLLREAEILEKKNHLANYLNKEVLCLSINGDLQPILRLL
SEKLKKSNSKEIDVYDPFKA
>Mature_339_residues
GFIDEVKLCLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGNIVFISDANLNTLLHFRYRRHIKADSGKNGAGRDRSGT
AGKDVILKVPVGAQIIDEESEEIIVDLDKPGMEFQVAQGGKGGLGNTNFKSSTNKAPRHFTYGQPGEEKHVLLKLKVLSD
VGIIGMPNAGKSKFLTRCSNSDTKVGDYPFTTVRPHLGMVKVDDSEVVIADIPGIITDAHLGVGLGHKFLKHIERCQILL
HLIDVTHDDVVSAYSCIHNELELYNSDLVEKEEIVVLNKCDLLREAEILEKKNHLANYLNKEVLCLSINGDLQPILRLLS
EKLKKSNSKEIDVYDPFKA

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=307, Percent_Identity=37.4592833876222, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI111955139, Length=294, Percent_Identity=36.3945578231293, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI111955063, Length=127, Percent_Identity=40.9448818897638, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=31.6176470588235, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789574, Length=307, Percent_Identity=49.8371335504886, Blast_Score=269, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17508313, Length=331, Percent_Identity=35.9516616314199, Blast_Score=148, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=30.8441558441558, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=143, Percent_Identity=33.5664335664336, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=195, Percent_Identity=34.8717948717949, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129375, Length=282, Percent_Identity=38.6524822695035, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24585318, Length=308, Percent_Identity=34.0909090909091, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24640873, Length=148, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640877, Length=148, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640875, Length=148, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37204; Mature: 37073

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFIDEVKLCLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGNIVFISDANLNTLLHFR
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
YRRHIKADSGKNGAGRDRSGTAGKDVILKVPVGAQIIDEESEEIIVDLDKPGMEFQVAQG
HHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCEEEEEECCCCCEEEEECC
GKGGLGNTNFKSSTNKAPRHFTYGQPGEEKHVLLKLKVLSDVGIIGMPNAGKSKFLTRCS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHCC
NSDTKVGDYPFTTVRPHLGMVKVDDSEVVIADIPGIITDAHLGVGLGHKFLKHIERCQIL
CCCCCCCCCCCCEECCCCCEEEECCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHH
LHLIDVTHDDVVSAYSCIHNELELYNSDLVEKEEIVVLNKCDLLREAEILEKKNHLANYL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
NKEVLCLSINGDLQPILRLLSEKLKKSNSKEIDVYDPFKA
CCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure 
GFIDEVKLCLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGNIVFISDANLNTLLHFR
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
YRRHIKADSGKNGAGRDRSGTAGKDVILKVPVGAQIIDEESEEIIVDLDKPGMEFQVAQG
HHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCEEEEEECCCCCEEEEECC
GKGGLGNTNFKSSTNKAPRHFTYGQPGEEKHVLLKLKVLSDVGIIGMPNAGKSKFLTRCS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHCC
NSDTKVGDYPFTTVRPHLGMVKVDDSEVVIADIPGIITDAHLGVGLGHKFLKHIERCQIL
CCCCCCCCCCCCEECCCCCEEEECCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHH
LHLIDVTHDDVVSAYSCIHNELELYNSDLVEKEEIVVLNKCDLLREAEILEKKNHLANYL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHC
NKEVLCLSINGDLQPILRLLSEKLKKSNSKEIDVYDPFKA
CCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA