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The map label for this gene is ytfL [C]

Identifier: 222527343

GI number: 222527343

Start: 5115879

End: 5117180

Strand: Reverse

Name: ytfL [C]

Synonym: Chy400_4131

Alternate gene names: 222527343

Gene position: 5117180-5115879 (Counterclockwise)

Preceding gene: 222527344

Following gene: 222527337

Centisome position: 97.12

GC content: 57.22

Gene sequence:

>1302_bases
ATGCAAGAACTGTTGATTATTATTGCGCTGGCGTTGGCTAACGGTTTATTCGCAGCAACCGAGCTGGCGGTGGTCTCGGC
CCGGCGAGGCCGGCTCGAACAACGTGTCGAAGAGGGGAGTCGTGGGGCGGCGGTTGCTCTGCAATTGCAGGAAGACCCCG
ACCGCTTTCTGGCAGCCGTGCAAATCGGGATTACGCTGATCGGGACGCTCAATGGTGTCTTTGCCGGGGCAACCCTCACC
AACCAGATTGCGCCCTGGGTGGCACGTTATGAATGGCTGGCACCTTATGCCGACCAGGTGGCTCAGTTTCTGGTTGTGTT
ACTGGTGACCTATCTATCACTGGTGTTGGGTGAACTGGTTCCTAAACGGATCGCTCTGCAAAGTGCGGAGTCCATCGCCA
CCCTTATGGCGCGGCCAATGTCACTGCTTGCCCGCATCAGTACGCCAATCATTATGTTATTGAGTGCCTCAACCCGGTTT
GTCCTGATGATCCTGGGTAGGGCAAACGTCGCCGAAGAACGGGTGACCGAGGAGGATATTCGAGCGCTGGTGCGCGAAGG
CACCGAAACCGGTGAGGTTGAACTGCAAGAACAGCAATTTATTGATCGGGTCTTCCGTTTCAGTGACCGGGCGGTGCGCC
ATATTATGACGCCGCGCCACGAAGTGGAAATGGTCGCCGCTGACCGCACCCTCGGCGAAGTCATTGATGAGTTGCTGGCA
AGCGGTTACTCGCGTTTTCCCGTCTACGAAGAGACACCCGATCAGATTGTGGGGATTGTCCATGTGCGCGATCTGCTTCT
CCTCTACCGGAAACAGGGCGAACAGGCGCTGGTGCGTGAAGCTGTTTCGCCACCGCTGTATGTCCCGGAAAACAGTCGTG
CCTCGGCGTTGTTGACGACGTTTCGCCGTAGTCGACGGCATATGGCGCTGGTGGTCGGTGAACTGGGCGGGATCGAAGGC
GTTGTCACTCTGGAAGATGTGTTGGAAGAGATTGTTGGTGAAATTGACGATGAGTATGATGATGCAACGCCCCCACCGAT
TGTGCGCCGCGAGGATGGCTCGTATCTGGTAGAGGGTTCGCTGCCGATTGATGAGGTGCGCACGCTGCTCGATGTTGACG
AGCTGCCCGAAGAGGAGACGTATCGCTACGAAACGCTGGCCGGTCTGGTGATCAGTCTGATCGGACAAATTCCCCGTGCC
GGTGATGTTGTGCATTGGGGGGAATGGCGGTTTGAGGTCGTGGATATGGATGGTCTGCGCGTCGATAAGGTGTTGATCTC
ACGCGAGCCGGCTGCCACCTGA

Upstream 100 bases:

>100_bases
CGTTGCGACAGATGTTCGTGACACTTCGACTGCACCTTGTCCACCGTTGTGGGCGGGGTGCAGTTTTTGGTCGTTCCAGG
GCTATAGCAGAGAAGAATCC

Downstream 100 bases:

>100_bases
AGAGGTTTTGGACCGTGGGCCGGTGATGTTGTTTATTGGGGTGAATGGCGGTTTGCGGTCGTGGATATGGATGGCTTGCG
CGTCGATAAGGTGTTGATCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MQELLIIIALALANGLFAATELAVVSARRGRLEQRVEEGSRGAAVALQLQEDPDRFLAAVQIGITLIGTLNGVFAGATLT
NQIAPWVARYEWLAPYADQVAQFLVVLLVTYLSLVLGELVPKRIALQSAESIATLMARPMSLLARISTPIIMLLSASTRF
VLMILGRANVAEERVTEEDIRALVREGTETGEVELQEQQFIDRVFRFSDRAVRHIMTPRHEVEMVAADRTLGEVIDELLA
SGYSRFPVYEETPDQIVGIVHVRDLLLLYRKQGEQALVREAVSPPLYVPENSRASALLTTFRRSRRHMALVVGELGGIEG
VVTLEDVLEEIVGEIDDEYDDATPPPIVRREDGSYLVEGSLPIDEVRTLLDVDELPEEETYRYETLAGLVISLIGQIPRA
GDVVHWGEWRFEVVDMDGLRVDKVLISREPAAT

Sequences:

>Translated_433_residues
MQELLIIIALALANGLFAATELAVVSARRGRLEQRVEEGSRGAAVALQLQEDPDRFLAAVQIGITLIGTLNGVFAGATLT
NQIAPWVARYEWLAPYADQVAQFLVVLLVTYLSLVLGELVPKRIALQSAESIATLMARPMSLLARISTPIIMLLSASTRF
VLMILGRANVAEERVTEEDIRALVREGTETGEVELQEQQFIDRVFRFSDRAVRHIMTPRHEVEMVAADRTLGEVIDELLA
SGYSRFPVYEETPDQIVGIVHVRDLLLLYRKQGEQALVREAVSPPLYVPENSRASALLTTFRRSRRHMALVVGELGGIEG
VVTLEDVLEEIVGEIDDEYDDATPPPIVRREDGSYLVEGSLPIDEVRTLLDVDELPEEETYRYETLAGLVISLIGQIPRA
GDVVHWGEWRFEVVDMDGLRVDKVLISREPAAT
>Mature_433_residues
MQELLIIIALALANGLFAATELAVVSARRGRLEQRVEEGSRGAAVALQLQEDPDRFLAAVQIGITLIGTLNGVFAGATLT
NQIAPWVARYEWLAPYADQVAQFLVVLLVTYLSLVLGELVPKRIALQSAESIATLMARPMSLLARISTPIIMLLSASTRF
VLMILGRANVAEERVTEEDIRALVREGTETGEVELQEQQFIDRVFRFSDRAVRHIMTPRHEVEMVAADRTLGEVIDELLA
SGYSRFPVYEETPDQIVGIVHVRDLLLLYRKQGEQALVREAVSPPLYVPENSRASALLTTFRRSRRHMALVVGELGGIEG
VVTLEDVLEEIVGEIDDEYDDATPPPIVRREDGSYLVEGSLPIDEVRTLLDVDELPEEETYRYETLAGLVISLIGQIPRA
GDVVHWGEWRFEVVDMDGLRVDKVLISREPAAT

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=360, Percent_Identity=28.8888888888889, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI94681046, Length=244, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI40068053, Length=259, Percent_Identity=25.0965250965251, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI40068055, Length=253, Percent_Identity=25.296442687747, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1790664, Length=431, Percent_Identity=28.538283062645, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI145693175, Length=415, Percent_Identity=25.7831325301205, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=37.1308016877637, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI87082033, Length=233, Percent_Identity=33.0472103004292, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786879, Length=274, Percent_Identity=30.2919708029197, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71980512, Length=370, Percent_Identity=24.3243243243243, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324512, Length=274, Percent_Identity=25.9124087591241, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48101; Mature: 48101

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELLIIIALALANGLFAATELAVVSARRGRLEQRVEEGSRGAAVALQLQEDPDRFLAAV
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
QIGITLIGTLNGVFAGATLTNQIAPWVARYEWLAPYADQVAQFLVVLLVTYLSLVLGELV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
PKRIALQSAESIATLMARPMSLLARISTPIIMLLSASTRFVLMILGRANVAEERVTEEDI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCHHHHHCCHHHH
RALVREGTETGEVELQEQQFIDRVFRFSDRAVRHIMTPRHEVEMVAADRTLGEVIDELLA
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SGYSRFPVYEETPDQIVGIVHVRDLLLLYRKQGEQALVREAVSPPLYVPENSRASALLTT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCHHHHHHH
FRRSRRHMALVVGELGGIEGVVTLEDVLEEIVGEIDDEYDDATPPPIVRREDGSYLVEGS
HHHCCHHHEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEECC
LPIDEVRTLLDVDELPEEETYRYETLAGLVISLIGQIPRAGDVVHWGEWRFEVVDMDGLR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEECCCCE
VDKVLISREPAAT
EHHHHCCCCCCCC
>Mature Secondary Structure
MQELLIIIALALANGLFAATELAVVSARRGRLEQRVEEGSRGAAVALQLQEDPDRFLAAV
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
QIGITLIGTLNGVFAGATLTNQIAPWVARYEWLAPYADQVAQFLVVLLVTYLSLVLGELV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
PKRIALQSAESIATLMARPMSLLARISTPIIMLLSASTRFVLMILGRANVAEERVTEEDI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCHHHHHCCHHHH
RALVREGTETGEVELQEQQFIDRVFRFSDRAVRHIMTPRHEVEMVAADRTLGEVIDELLA
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SGYSRFPVYEETPDQIVGIVHVRDLLLLYRKQGEQALVREAVSPPLYVPENSRASALLTT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECCCCCCHHHHHHH
FRRSRRHMALVVGELGGIEGVVTLEDVLEEIVGEIDDEYDDATPPPIVRREDGSYLVEGS
HHHCCHHHEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEECC
LPIDEVRTLLDVDELPEEETYRYETLAGLVISLIGQIPRAGDVVHWGEWRFEVVDMDGLR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEECCCCE
VDKVLISREPAAT
EHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]