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The map label for this gene is cdsA [H]

Identifier: 222527072

GI number: 222527072

Start: 4795824

End: 4796651

Strand: Direct

Name: cdsA [H]

Synonym: Chy400_3851

Alternate gene names: 222527072

Gene position: 4795824-4796651 (Clockwise)

Preceding gene: 222527071

Following gene: 222527073

Centisome position: 91.02

GC content: 56.52

Gene sequence:

>828_bases
GTGGCAAGTGTGGTAGTCCTGCTACCACTGATTATTGCCGGTGTCTGGTGGCCGCCGACCACTGCATTGCTGGCCGGCCT
CGTCATTGCACTGGCAATCAGCGAGTTGTTTGCCATTTTTCGTCAGGGTGGTTATCAGCCGCGCCTGATAGAAGGAATTG
CCATCGGTTGGCTGATCTGCACGGCAACCTTTTTTCAACCGCTCACAACTGTCGATCTGGTCCTGGTGGCGCTGGTCGTT
TCGATCCTCGGTGCCCTGATCGCCGAAATTGCGCGCCGAGATCGGCAAACTAGCCTGCTTAGCTGGGCATTGACGTTCGC
CGGTGCGTACTACGTGAGCGGTCTGCTCAGCAGCTATCTTTTATTACGTCAACTCGAATTGCCGTTGCAGAACGGCTGGC
TGGCCTTCGCCAACATCCCCCCTGGCGCGGCCTGGGTCTTCTTCACCCTGGCCATCACCTGGCTGCAAGATACCGGCGCA
TTCTTTGTTGGTCGTGCCTTCGGACGCACCAAAATGGCACCTATCCTCAGCCCGAAAAAGAGTTGGGAGGGCTTTGCCGG
CGGGATGGTTGCCGCTATCGCGACTGCCCTGTTCTGCGTTCCCCTGCTGGGACTCCCCATTACGCTGCTTGAAGCGGCTA
TTCTGGGTGTGATCGCCGGTATTTTTGGTCCGCTCGGCGATCTTGCCGAGTCGCTGATCAAACGCCAGGTCGGCGTCAAA
GATTCAGGGTATATTATTCCTGGTCACGGTGGGATTCTGGATCGCATCGATAGCATCCTCTTCACCGGGCCGGTTGTCTA
CTACATGATCGTATTGTTTACAAGGTAA

Upstream 100 bases:

>100_bases
TTTCGACCCGAGCATCTGCATCAGGCAATTCTTGACTATGGACGGCGCGAACGCCGCTTCGGCGGACTCCCCAAGCCGGG
CTAATACGCTGGCAATTCGT

Downstream 100 bases:

>100_bases
GGCAGGAACGGGTCATGATTACAACCATCACGACCAGCCGGGAACAGTGGACTCCCGATACGGCACTGGCCGGCTTTGAA
ACGAGGTCGATCAATCTGCG

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MASVVVLLPLIIAGVWWPPTTALLAGLVIALAISELFAIFRQGGYQPRLIEGIAIGWLICTATFFQPLTTVDLVLVALVV
SILGALIAEIARRDRQTSLLSWALTFAGAYYVSGLLSSYLLLRQLELPLQNGWLAFANIPPGAAWVFFTLAITWLQDTGA
FFVGRAFGRTKMAPILSPKKSWEGFAGGMVAAIATALFCVPLLGLPITLLEAAILGVIAGIFGPLGDLAESLIKRQVGVK
DSGYIIPGHGGILDRIDSILFTGPVVYYMIVLFTR

Sequences:

>Translated_275_residues
MASVVVLLPLIIAGVWWPPTTALLAGLVIALAISELFAIFRQGGYQPRLIEGIAIGWLICTATFFQPLTTVDLVLVALVV
SILGALIAEIARRDRQTSLLSWALTFAGAYYVSGLLSSYLLLRQLELPLQNGWLAFANIPPGAAWVFFTLAITWLQDTGA
FFVGRAFGRTKMAPILSPKKSWEGFAGGMVAAIATALFCVPLLGLPITLLEAAILGVIAGIFGPLGDLAESLIKRQVGVK
DSGYIIPGHGGILDRIDSILFTGPVVYYMIVLFTR
>Mature_274_residues
ASVVVLLPLIIAGVWWPPTTALLAGLVIALAISELFAIFRQGGYQPRLIEGIAIGWLICTATFFQPLTTVDLVLVALVVS
ILGALIAEIARRDRQTSLLSWALTFAGAYYVSGLLSSYLLLRQLELPLQNGWLAFANIPPGAAWVFFTLAITWLQDTGAF
FVGRAFGRTKMAPILSPKKSWEGFAGGMVAAIATALFCVPLLGLPITLLEAAILGVIAGIFGPLGDLAESLIKRQVGVKD
SGYIIPGHGGILDRIDSILFTGPVVYYMIVLFTR

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=148, Percent_Identity=41.2162162162162, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787677, Length=134, Percent_Identity=46.2686567164179, Blast_Score=107, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29461; Mature: 29329

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVVVLLPLIIAGVWWPPTTALLAGLVIALAISELFAIFRQGGYQPRLIEGIAIGWLIC
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TATFFQPLTTVDLVLVALVVSILGALIAEIARRDRQTSLLSWALTFAGAYYVSGLLSSYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRQLELPLQNGWLAFANIPPGAAWVFFTLAITWLQDTGAFFVGRAFGRTKMAPILSPKK
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCH
SWEGFAGGMVAAIATALFCVPLLGLPITLLEAAILGVIAGIFGPLGDLAESLIKRQVGVK
HCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
DSGYIIPGHGGILDRIDSILFTGPVVYYMIVLFTR
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASVVVLLPLIIAGVWWPPTTALLAGLVIALAISELFAIFRQGGYQPRLIEGIAIGWLIC
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TATFFQPLTTVDLVLVALVVSILGALIAEIARRDRQTSLLSWALTFAGAYYVSGLLSSYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRQLELPLQNGWLAFANIPPGAAWVFFTLAITWLQDTGAFFVGRAFGRTKMAPILSPKK
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCH
SWEGFAGGMVAAIATALFCVPLLGLPITLLEAAILGVIAGIFGPLGDLAESLIKRQVGVK
HCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
DSGYIIPGHGGILDRIDSILFTGPVVYYMIVLFTR
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]