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The map label for this gene is ppa [H]

Identifier: 222526808

GI number: 222526808

Start: 4458991

End: 4459542

Strand: Direct

Name: ppa [H]

Synonym: Chy400_3582

Alternate gene names: 222526808

Gene position: 4458991-4459542 (Clockwise)

Preceding gene: 222526801

Following gene: 222526809

Centisome position: 84.63

GC content: 56.16

Gene sequence:

>552_bases
ATGCAGAACCTATGGCACGATCTGGAACCCGGTCCAGACGTTCCGAATGTCATTCATGTTGTAGTTGAAATTCCAAAGGG
ATCACGCAACAAATATGAATTTGACAAGCGGATTGGGGCATTCCGCCTTGATCGCGTGCTCTACTCTGCCGTGCAATACC
CCGGCGATTACGGCTTTATGCCGCAGACGTACTACGATGATGGCGATCCGCTCGACGTGCTGGTGATGACCAACCTGCCC
ACCTTCCCCGGTTGTATTGTCGAAGCACGGCCACTGGGGTTGTTCCGTATGCTCGATAAGGGTGAGCCGGATGACAAAGT
GCTCGCCGTGCTACAGTACGATCCCTTCTTCGCCGACTACCACAACTACACGGCACTGCCGGCGCACTATCTGCGCGAAG
TCGAGCACTTCTTTACCGTTTACAAAGACCTGGAGGGCTCACGGGTCGAACCGGTCGGCTGGGAGTCGGCGGATGTGGCT
CGCGAGCGGATTCAGTACTCGATAGATCGCTACTGGGATATGCGCGCCGGTCGCGTGCTCAAACGTGCCTGA

Upstream 100 bases:

>100_bases
CAGCGAACGCTGCCTGCATCCAGTCACCGTGTGATTATTTTACATGTTATAATCTTGCGGTAATAGGGCTTAAGATGCTG
ATGTACAAGTGAGGCTACCG

Downstream 100 bases:

>100_bases
TCGGATGGTCATGACTTCACGCCGTTCACTTTCGCATCGCACAGCCTATTCGGCGGGCGGTGTTATTTATCGGATTGTTG
CCACGCAGATCGAAGTGGCA

Product: Inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MQNLWHDLEPGPDVPNVIHVVVEIPKGSRNKYEFDKRIGAFRLDRVLYSAVQYPGDYGFMPQTYYDDGDPLDVLVMTNLP
TFPGCIVEARPLGLFRMLDKGEPDDKVLAVLQYDPFFADYHNYTALPAHYLREVEHFFTVYKDLEGSRVEPVGWESADVA
RERIQYSIDRYWDMRAGRVLKRA

Sequences:

>Translated_183_residues
MQNLWHDLEPGPDVPNVIHVVVEIPKGSRNKYEFDKRIGAFRLDRVLYSAVQYPGDYGFMPQTYYDDGDPLDVLVMTNLP
TFPGCIVEARPLGLFRMLDKGEPDDKVLAVLQYDPFFADYHNYTALPAHYLREVEHFFTVYKDLEGSRVEPVGWESADVA
RERIQYSIDRYWDMRAGRVLKRA
>Mature_183_residues
MQNLWHDLEPGPDVPNVIHVVVEIPKGSRNKYEFDKRIGAFRLDRVLYSAVQYPGDYGFMPQTYYDDGDPLDVLVMTNLP
TFPGCIVEARPLGLFRMLDKGEPDDKVLAVLQYDPFFADYHNYTALPAHYLREVEHFFTVYKDLEGSRVEPVGWESADVA
RERIQYSIDRYWDMRAGRVLKRA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=164, Percent_Identity=39.6341463414634, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319483, Length=157, Percent_Identity=28.0254777070064, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21295; Mature: 21295

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLWHDLEPGPDVPNVIHVVVEIPKGSRNKYEFDKRIGAFRLDRVLYSAVQYPGDYGFM
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PQTYYDDGDPLDVLVMTNLPTFPGCIVEARPLGLFRMLDKGEPDDKVLAVLQYDPFFADY
CCCCCCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHCCCCCCCCEEEEEECCCCCCCC
HNYTALPAHYLREVEHFFTVYKDLEGSRVEPVGWESADVARERIQYSIDRYWDMRAGRVL
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRA
HCC
>Mature Secondary Structure
MQNLWHDLEPGPDVPNVIHVVVEIPKGSRNKYEFDKRIGAFRLDRVLYSAVQYPGDYGFM
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PQTYYDDGDPLDVLVMTNLPTFPGCIVEARPLGLFRMLDKGEPDDKVLAVLQYDPFFADY
CCCCCCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHCCCCCCCCEEEEEECCCCCCCC
HNYTALPAHYLREVEHFFTVYKDLEGSRVEPVGWESADVARERIQYSIDRYWDMRAGRVL
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]