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The map label for this gene is muT4 [H]

Identifier: 222526809

GI number: 222526809

Start: 4459553

End: 4460011

Strand: Direct

Name: muT4 [H]

Synonym: Chy400_3583

Alternate gene names: 222526809

Gene position: 4459553-4460011 (Clockwise)

Preceding gene: 222526808

Following gene: 222526810

Centisome position: 84.64

GC content: 58.61

Gene sequence:

>459_bases
ATGACTTCACGCCGTTCACTTTCGCATCGCACAGCCTATTCGGCGGGCGGTGTTATTTATCGGATTGTTGCCACGCAGAT
CGAAGTGGCACTGATTGCAACCGATCGTGGTGAGCGTTGGGGGCTGCCCAAAGGGCACGTAAACCGGGGCGAAACCGCGG
AGGCTGCGGCTGTGCGCGAAATAGCCGAAGAGACCGGGCTTGAGGGCGTTGTGGAGCGGCATCTGGCGACAATTGAGTAC
TGGTTTCGCTCCGGTCATGGCCGGGTCCACAAGTATGTCGATCTGTTTCTGCTCCGCTATGAACGGGGTGAGGTGCGACC
ACAGATCGGCGAAGTTGACGATGCTCGCTGGTTCCCGCTCGATGAAGCGCTCCAGCGGGTTTCATTCGAGCGGGAACGTG
ATGTGCTGTTGTTGGCCCGGCAGGCACTCTGTGATGCGAGCGGTAATGCAAAGGTATGA

Upstream 100 bases:

>100_bases
GAGTCGGCGGATGTGGCTCGCGAGCGGATTCAGTACTCGATAGATCGCTACTGGGATATGCGCGCCGGTCGCGTGCTCAA
ACGTGCCTGATCGGATGGTC

Downstream 100 bases:

>100_bases
TCTACACTATCGAAGTGCAACTGGATGAAGGTATCACCGCCGATAGCGAGCTGGTTGAACGCGCTGCGGCGGCAGTGCTG
GCCGCCGAGCAGATGCCGGA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTSRRSLSHRTAYSAGGVIYRIVATQIEVALIATDRGERWGLPKGHVNRGETAEAAAVREIAEETGLEGVVERHLATIEY
WFRSGHGRVHKYVDLFLLRYERGEVRPQIGEVDDARWFPLDEALQRVSFERERDVLLLARQALCDASGNAKV

Sequences:

>Translated_152_residues
MTSRRSLSHRTAYSAGGVIYRIVATQIEVALIATDRGERWGLPKGHVNRGETAEAAAVREIAEETGLEGVVERHLATIEY
WFRSGHGRVHKYVDLFLLRYERGEVRPQIGEVDDARWFPLDEALQRVSFERERDVLLLARQALCDASGNAKV
>Mature_151_residues
TSRRSLSHRTAYSAGGVIYRIVATQIEVALIATDRGERWGLPKGHVNRGETAEAAAVREIAEETGLEGVVERHLATIEYW
FRSGHGRVHKYVDLFLLRYERGEVRPQIGEVDDARWFPLDEALQRVSFERERDVLLLARQALCDASGNAKV

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 17189; Mature: 17057

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRRSLSHRTAYSAGGVIYRIVATQIEVALIATDRGERWGLPKGHVNRGETAEAAAVRE
CCCCCCCHHHHHHCCCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
IAEETGLEGVVERHLATIEYWFRSGHGRVHKYVDLFLLRYERGEVRPQIGEVDDARWFPL
HHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
DEALQRVSFERERDVLLLARQALCDASGNAKV
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSRRSLSHRTAYSAGGVIYRIVATQIEVALIATDRGERWGLPKGHVNRGETAEAAAVRE
CCCCCCHHHHHHCCCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
IAEETGLEGVVERHLATIEYWFRSGHGRVHKYVDLFLLRYERGEVRPQIGEVDDARWFPL
HHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
DEALQRVSFERERDVLLLARQALCDASGNAKV
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]