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The map label for this gene is aapQ [H]

Identifier: 222526722

GI number: 222526722

Start: 4352245

End: 4353447

Strand: Direct

Name: aapQ [H]

Synonym: Chy400_3495

Alternate gene names: 222526722

Gene position: 4352245-4353447 (Clockwise)

Preceding gene: 222526721

Following gene: 222526723

Centisome position: 82.6

GC content: 49.88

Gene sequence:

>1203_bases
ATGGCTGTTGGTTCGCCATCGGTTCCTCCCGGCAAAATAAATATTCCTTTTTATCGTGATACGCGGATTATTGCGATCAT
TGTTCAAGTGGTGTTTGCTATTTTGGTGATCGCACTGGTTTGGTTTTTGTATTCAAATATGATTAATGGCCTGCGCCAGG
CTAATCTGTTGCCTACGTTCTCTTTTCTGTCTGTGCCGGCCGGCTTTCCTATTTCTGAAAGTGTTATAGAGTACGATCCC
TCCATGACGTATGGGCGAGCGTTTATTGTTGGTATTTTGAATACCGTCCGTGTGGCTGTAATCGGTATTATTCTTGCTAC
GCTACTGGGACTAATTCTCGGTATTGCTCGCCTCTCTGATAACTGGTTGTTGCGTAATGTGGCATTAGTCTATGTTGAAA
TTGTGCGTAATGTTCCTTTGCTTTTGCAGTTAATCTTTTGGTTTTCGCTTACCCGCCTTTTTCCCCGTATTCAGGAGAGT
ATTGATGTCGGCGGATTGATGTTTTTGCATAATCGCGGCATTACTCTGGCCTGGCCGCAGGCGGGTAATGATTTCGATGC
CTGGATGGTGTGGGTCTATGCCGGTATTGTGATTGGGATCGTCTTCTACGTGGTACGCCGGATTCAATTTGTGCGTCGTG
ACCGACCCGGCGTTGCCTTGCCGTATGCATTGCTCATCGCACTGGGTGTCGCGCTGCTCGGCTTTCTGGTCACCTATCTG
ACGACGGGTGTCTGGCCGGTTAGCCTTTCCATACCAGTGTTGCAGCGCTTTAATTTCGACGGTGGCATAACGGTTACCAA
TAGCTTCGCAGCCTTGTTGATTGGCTTAGTGATTTACACCGCAGTCTTCATCGGCGAGATTGTGCGCAGCGGTATTCTGG
CGGTCAGCAAAGGCCAGCGTGAAGCAGCGCGTGCCCTCGGTCTGACCCCCGGGCAGACAATGCGGCTGGTGATCCTGCCC
CAGGCGCTGCGAGTGATTATTCCGCCACTGACCAGTCAGTATCTCAACCTGACCAAGAACAGCAGTCTGGCAATTGCAAT
TGCTTATCCCGATCTCTTCTACGTCGCCAATACGATTAACAATCAGACCGGCCAGGCTGTACCGGTGATCTTGATGCTCA
TGGCCAGTTATCTTTCGGTCAGTTTGCTGACGTCGCTGTTTATGAACTGGTATAACCGTCGCATCCAGCTTGTCGAGCGA
TAA

Upstream 100 bases:

>100_bases
CTCGCAGTGTTGCAAGGCTATCTGGTCGAAGCACTGTTCCAAATGCAATCTGCGTTTATGTGGATTGGTGCCTCAAGGTC
TTACCCTTCAGGAGAAAGTT

Downstream 100 bases:

>100_bases
GGAGACGCCTGTGGCTACTGAAGTTAGTCGTCCAACTTCGCGCCGTGCACCGCGTCAGCAGATTGGTCTGATCGAGTGGT
TGCGCAAAAATCTCTTTTCA

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAVGSPSVPPGKINIPFYRDTRIIAIIVQVVFAILVIALVWFLYSNMINGLRQANLLPTFSFLSVPAGFPISESVIEYDP
SMTYGRAFIVGILNTVRVAVIGIILATLLGLILGIARLSDNWLLRNVALVYVEIVRNVPLLLQLIFWFSLTRLFPRIQES
IDVGGLMFLHNRGITLAWPQAGNDFDAWMVWVYAGIVIGIVFYVVRRIQFVRRDRPGVALPYALLIALGVALLGFLVTYL
TTGVWPVSLSIPVLQRFNFDGGITVTNSFAALLIGLVIYTAVFIGEIVRSGILAVSKGQREAARALGLTPGQTMRLVILP
QALRVIIPPLTSQYLNLTKNSSLAIAIAYPDLFYVANTINNQTGQAVPVILMLMASYLSVSLLTSLFMNWYNRRIQLVER

Sequences:

>Translated_400_residues
MAVGSPSVPPGKINIPFYRDTRIIAIIVQVVFAILVIALVWFLYSNMINGLRQANLLPTFSFLSVPAGFPISESVIEYDP
SMTYGRAFIVGILNTVRVAVIGIILATLLGLILGIARLSDNWLLRNVALVYVEIVRNVPLLLQLIFWFSLTRLFPRIQES
IDVGGLMFLHNRGITLAWPQAGNDFDAWMVWVYAGIVIGIVFYVVRRIQFVRRDRPGVALPYALLIALGVALLGFLVTYL
TTGVWPVSLSIPVLQRFNFDGGITVTNSFAALLIGLVIYTAVFIGEIVRSGILAVSKGQREAARALGLTPGQTMRLVILP
QALRVIIPPLTSQYLNLTKNSSLAIAIAYPDLFYVANTINNQTGQAVPVILMLMASYLSVSLLTSLFMNWYNRRIQLVER
>Mature_399_residues
AVGSPSVPPGKINIPFYRDTRIIAIIVQVVFAILVIALVWFLYSNMINGLRQANLLPTFSFLSVPAGFPISESVIEYDPS
MTYGRAFIVGILNTVRVAVIGIILATLLGLILGIARLSDNWLLRNVALVYVEIVRNVPLLLQLIFWFSLTRLFPRIQESI
DVGGLMFLHNRGITLAWPQAGNDFDAWMVWVYAGIVIGIVFYVVRRIQFVRRDRPGVALPYALLIALGVALLGFLVTYLT
TGVWPVSLSIPVLQRFNFDGGITVTNSFAALLIGLVIYTAVFIGEIVRSGILAVSKGQREAARALGLTPGQTMRLVILPQ
ALRVIIPPLTSQYLNLTKNSSLAIAIAYPDLFYVANTINNQTGQAVPVILMLMASYLSVSLLTSLFMNWYNRRIQLVER

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=361, Percent_Identity=45.1523545706371, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1788226, Length=128, Percent_Identity=42.1875, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786873, Length=122, Percent_Identity=37.7049180327869, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786874, Length=129, Percent_Identity=34.1085271317829, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787030, Length=132, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082239, Length=193, Percent_Identity=32.1243523316062, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788645, Length=137, Percent_Identity=29.9270072992701, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 44240; Mature: 44109

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGSPSVPPGKINIPFYRDTRIIAIIVQVVFAILVIALVWFLYSNMINGLRQANLLPTF
CCCCCCCCCCCEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SFLSVPAGFPISESVIEYDPSMTYGRAFIVGILNTVRVAVIGIILATLLGLILGIARLSD
HHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NWLLRNVALVYVEIVRNVPLLLQLIFWFSLTRLFPRIQESIDVGGLMFLHNRGITLAWPQ
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCC
AGNDFDAWMVWVYAGIVIGIVFYVVRRIQFVRRDRPGVALPYALLIALGVALLGFLVTYL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TTGVWPVSLSIPVLQRFNFDGGITVTNSFAALLIGLVIYTAVFIGEIVRSGILAVSKGQR
HCCCCEEEECHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHH
EAARALGLTPGQTMRLVILPQALRVIIPPLTSQYLNLTKNSSLAIAIAYPDLFYVANTIN
HHHHHHCCCCCCCEEEEEEHHHHHHHCCCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHC
NQTGQAVPVILMLMASYLSVSLLTSLFMNWYNRRIQLVER
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVGSPSVPPGKINIPFYRDTRIIAIIVQVVFAILVIALVWFLYSNMINGLRQANLLPTF
CCCCCCCCCCEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SFLSVPAGFPISESVIEYDPSMTYGRAFIVGILNTVRVAVIGIILATLLGLILGIARLSD
HHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NWLLRNVALVYVEIVRNVPLLLQLIFWFSLTRLFPRIQESIDVGGLMFLHNRGITLAWPQ
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCC
AGNDFDAWMVWVYAGIVIGIVFYVVRRIQFVRRDRPGVALPYALLIALGVALLGFLVTYL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TTGVWPVSLSIPVLQRFNFDGGITVTNSFAALLIGLVIYTAVFIGEIVRSGILAVSKGQR
HCCCCEEEECHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHH
EAARALGLTPGQTMRLVILPQALRVIIPPLTSQYLNLTKNSSLAIAIAYPDLFYVANTIN
HHHHHHCCCCCCCEEEEEEHHHHHHHCCCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHC
NQTGQAVPVILMLMASYLSVSLLTSLFMNWYNRRIQLVER
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]