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The map label for this gene is rpiA

Identifier: 222526683

GI number: 222526683

Start: 4304600

End: 4305319

Strand: Reverse

Name: rpiA

Synonym: Chy400_3453

Alternate gene names: 222526683

Gene position: 4305319-4304600 (Counterclockwise)

Preceding gene: 222526684

Following gene: 222526682

Centisome position: 81.71

GC content: 59.31

Gene sequence:

>720_bases
ATGAATACAACGTCAACTGAGACACGCAAAGCAATGGCGGCAGCGGCGGCGGTAGCCCTGGTACGGCCAGGGATGGTGAT
CGGGTTGGGCTTTGGCAGTACTGCCGCCTACGCAACACGCATGATTGCCGAACGTCTGCACCAGGGTGATCTGAACGACA
TCGTTGGTGTACCGTGTGCCGAGGGCACTGCCCAACTGGCTCGCGAACTGGGTATTCCGCTCACAACGCTCGACGAAGTC
GCTGCGGTGGATTTGACCATTGACGGCGCTGACGAGGTTGATCCGCAACTATCGTTAATAAAAGGAGGCGGCGGAGCACT
ATTGCGTGAAAAGATGGTCGCGCAGGCCAGTCGGCGGGTCGCGATTATTGTTGATGACAGCAAACTGTCACCAGCCCTCG
GTACACGCTTTGCCTTACCGCTCGAAGTCGTCGATTTTGGCTGGCGCGCCACTGCACGCTGGCTGGAGGCACAAGGCGGA
ACGGTGCAGCTTCGCCTGCGGGCCGATGGTCAACCCTTCCGTACCGATCAGGGAAACCTCATTCTCGATTGGAAGTGCGG
CCCACTCAATGATCCGGCAGCGCTGGCAGCTCAGCTATCAGCGCGAGCCGGCATTGTCGAACACGGTCTGTTCATTGGTC
TGGCAACCGATCTCTTCGTAGCCGGCCCGGACGGTGTGCAGCACGTGACCACCAGCGATTGCGGTACAATAGCCTGGTAG

Upstream 100 bases:

>100_bases
GGTCAATGTAGCAGCGCCGACGGCTGCCCAATTGCACACCCGTTCAGCGTGGCTGCAAAGAATGGTCTAGGCACTTCACA
GAACAAGAGTGACAGCGACG

Downstream 100 bases:

>100_bases
GCTTTCATTCGCGGAAGGCGTGGATTGAAACCATCATAACAACAGGGATGCTATGCGGCTTGCGCCTTCAATTCTCACGG
CTGATTTTGCGCGTTTGGGC

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNTTSTETRKAMAAAAAVALVRPGMVIGLGFGSTAAYATRMIAERLHQGDLNDIVGVPCAEGTAQLARELGIPLTTLDEV
AAVDLTIDGADEVDPQLSLIKGGGGALLREKMVAQASRRVAIIVDDSKLSPALGTRFALPLEVVDFGWRATARWLEAQGG
TVQLRLRADGQPFRTDQGNLILDWKCGPLNDPAALAAQLSARAGIVEHGLFIGLATDLFVAGPDGVQHVTTSDCGTIAW

Sequences:

>Translated_239_residues
MNTTSTETRKAMAAAAAVALVRPGMVIGLGFGSTAAYATRMIAERLHQGDLNDIVGVPCAEGTAQLARELGIPLTTLDEV
AAVDLTIDGADEVDPQLSLIKGGGGALLREKMVAQASRRVAIIVDDSKLSPALGTRFALPLEVVDFGWRATARWLEAQGG
TVQLRLRADGQPFRTDQGNLILDWKCGPLNDPAALAAQLSARAGIVEHGLFIGLATDLFVAGPDGVQHVTTSDCGTIAW
>Mature_239_residues
MNTTSTETRKAMAAAAAVALVRPGMVIGLGFGSTAAYATRMIAERLHQGDLNDIVGVPCAEGTAQLARELGIPLTTLDEV
AAVDLTIDGADEVDPQLSLIKGGGGALLREKMVAQASRRVAIIVDDSKLSPALGTRFALPLEVVDFGWRATARWLEAQGG
TVQLRLRADGQPFRTDQGNLILDWKCGPLNDPAALAAQLSARAGIVEHGLFIGLATDLFVAGPDGVQHVTTSDCGTIAW

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=227, Percent_Identity=37.8854625550661, Blast_Score=140, Evalue=8e-34,
Organism=Escherichia coli, GI1789280, Length=229, Percent_Identity=36.2445414847162, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17551758, Length=234, Percent_Identity=38.4615384615385, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324669, Length=216, Percent_Identity=31.4814814814815, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281364072, Length=207, Percent_Identity=35.2657004830918, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_CHLAA (A9WIA0)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636781.1
- ProteinModelPortal:   A9WIA0
- SMR:   A9WIA0
- GeneID:   5825001
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_3198
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   CLSK954875
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24996; Mature: 24996

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTSTETRKAMAAAAAVALVRPGMVIGLGFGSTAAYATRMIAERLHQGDLNDIVGVPCA
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCCCCCC
EGTAQLARELGIPLTTLDEVAAVDLTIDGADEVDPQLSLIKGGGGALLREKMVAQASRRV
CCHHHHHHHHCCCCEECCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCE
AIIVDDSKLSPALGTRFALPLEVVDFGWRATARWLEAQGGTVQLRLRADGQPFRTDQGNL
EEEEECCCCCCCCCCEEECCHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCE
ILDWKCGPLNDPAALAAQLSARAGIVEHGLFIGLATDLFVAGPDGVQHVTTSDCGTIAW
EEEEECCCCCCHHHHHHHHHHHCCHHHHCEEEEEECCEEEECCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MNTTSTETRKAMAAAAAVALVRPGMVIGLGFGSTAAYATRMIAERLHQGDLNDIVGVPCA
CCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCCCCCC
EGTAQLARELGIPLTTLDEVAAVDLTIDGADEVDPQLSLIKGGGGALLREKMVAQASRRV
CCHHHHHHHHCCCCEECCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCE
AIIVDDSKLSPALGTRFALPLEVVDFGWRATARWLEAQGGTVQLRLRADGQPFRTDQGNL
EEEEECCCCCCCCCCEEECCHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCE
ILDWKCGPLNDPAALAAQLSARAGIVEHGLFIGLATDLFVAGPDGVQHVTTSDCGTIAW
EEEEECCCCCCHHHHHHHHHHHCCHHHHCEEEEEECCEEEECCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA