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The map label for this gene is yodQ [H]

Identifier: 222526089

GI number: 222526089

Start: 3511823

End: 3513112

Strand: Direct

Name: yodQ [H]

Synonym: Chy400_2846

Alternate gene names: 222526089

Gene position: 3511823-3513112 (Clockwise)

Preceding gene: 222526088

Following gene: 222526090

Centisome position: 66.65

GC content: 61.01

Gene sequence:

>1290_bases
ATGCAACATCTGCATCCGATTGAGCAACGAGTGCTCAGCGCCATCAACGACGATGGCTTATTGAAGGCACTGGCCGATCT
GGTCAGTATCCCCAGCCTCGACGGCACTACGGCTGAAAATGAAGCCCAAGAGGCCGTCGCTGCGTTGCTACAATCCCAAT
CAATGACGGTTGATCGGTGGGAAATCGATCTACCCCGTTTGTATGCTCATCCTGATTGCAGTTGGGAAGTGCCGCGTGAG
CGAGCGCTCGGCGTCGTCGGAATTCTGGGTGAGGATCGCGGTGGACGTAGCCTGATCTTCAACGGCCACGTTGACGTTGT
GCCGGCTGGTGACCGACGCCTGTGGCATAGTGATCCGTGGCAGGCGACTATCGTCAATGGCCGGGTCTACGGGCGCGGTG
CGCTGGATATGAAGGGAGGGCTGTGCTGTGCCATCTTTGCTGCCCGGGCCATCGCGGCTGCGGGTGTCCGGCTCCGTGGC
CGTCTCGTGATCCAGAGTGTGATCGGCGAAGAAGATGGCGGTCTCGGCACACTGGCAGCCATTTTGCGTGGCCACACTGC
CGATGCCGCGATTGTGGCCGAGCCAACGGAATTGAAAGTCGCACCGGCTCAGGCCGGCGCACACAATTTCCGCTTAACGG
TGTATGGGGCGGCGGCGCACGGCTGTGTGCGCGAAGAGGGTGTCAGTGCAATTGAAAAATTTGCACCGCTACACCAGGCC
ATCATCGCGCTCGAACGTACTCGCAACGAACGCTTGCGTGCAGCCGACAGCAGCGGTCTCTTCTCGCGCTACCGTACCCC
CAATGCTATCTGTATCGGTGTGGTGCGGGCAGGCGAATGGGCTTCTTCCGAAGCCGAGCAACTGGTCGCCGAAGGCCGTT
ACGGGATTGGGGTCGGCGAAGACCCGGCTATTGCACGCACCGAGCTGGAGCAGACGGTAGCCGCTGCTGCGGCCCAAGAC
CCCTGGCTGCGCGATCATCCGCCAATGCTGGAATGGTGGGGTGGGCGGTTTGATCCGGCCAGTACGCCCATGGACTCACC
TGTTGTCCAAACCCTTGCCGCCTGCGATCAGGCGGTGCGGGGCACACCTGCCACATTTGAAGGCATGACCTACGGCGCCG
ATATGCGGCTACTGGTCAATGTTGGCGGTATTCCTACCGTCCTCTACGGGCCGGGTGATGTCCGCAATGCCCACCGACCG
AACGAGTCGGTTGCCATCGTCGATTTACAGACAGCCACTCGCGTCCTGGCCCTCACTGCCCTTCGCTTCTGCGGTTACGA
TGAGGAATAG

Upstream 100 bases:

>100_bases
GGTTGCGCGTATTGCGGTTGACCTGGGGCGCATAACGTGATCACATCGTGAGTAGACATCAATACCAGACAATCACAGCT
AAGGAGAGTACATTCCCGCT

Downstream 100 bases:

>100_bases
TTGATGAAAACCAGTCTCCAGATCGCTGCCGAAGCCCGGCTAGAGCCAATCGCTGCCATTGCCGAACGGCTTGGCCTGCC
TGTCAGGTACCTCGAACCGT

Product: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MQHLHPIEQRVLSAINDDGLLKALADLVSIPSLDGTTAENEAQEAVAALLQSQSMTVDRWEIDLPRLYAHPDCSWEVPRE
RALGVVGILGEDRGGRSLIFNGHVDVVPAGDRRLWHSDPWQATIVNGRVYGRGALDMKGGLCCAIFAARAIAAAGVRLRG
RLVIQSVIGEEDGGLGTLAAILRGHTADAAIVAEPTELKVAPAQAGAHNFRLTVYGAAAHGCVREEGVSAIEKFAPLHQA
IIALERTRNERLRAADSSGLFSRYRTPNAICIGVVRAGEWASSEAEQLVAEGRYGIGVGEDPAIARTELEQTVAAAAAQD
PWLRDHPPMLEWWGGRFDPASTPMDSPVVQTLAACDQAVRGTPATFEGMTYGADMRLLVNVGGIPTVLYGPGDVRNAHRP
NESVAIVDLQTATRVLALTALRFCGYDEE

Sequences:

>Translated_429_residues
MQHLHPIEQRVLSAINDDGLLKALADLVSIPSLDGTTAENEAQEAVAALLQSQSMTVDRWEIDLPRLYAHPDCSWEVPRE
RALGVVGILGEDRGGRSLIFNGHVDVVPAGDRRLWHSDPWQATIVNGRVYGRGALDMKGGLCCAIFAARAIAAAGVRLRG
RLVIQSVIGEEDGGLGTLAAILRGHTADAAIVAEPTELKVAPAQAGAHNFRLTVYGAAAHGCVREEGVSAIEKFAPLHQA
IIALERTRNERLRAADSSGLFSRYRTPNAICIGVVRAGEWASSEAEQLVAEGRYGIGVGEDPAIARTELEQTVAAAAAQD
PWLRDHPPMLEWWGGRFDPASTPMDSPVVQTLAACDQAVRGTPATFEGMTYGADMRLLVNVGGIPTVLYGPGDVRNAHRP
NESVAIVDLQTATRVLALTALRFCGYDEE
>Mature_429_residues
MQHLHPIEQRVLSAINDDGLLKALADLVSIPSLDGTTAENEAQEAVAALLQSQSMTVDRWEIDLPRLYAHPDCSWEVPRE
RALGVVGILGEDRGGRSLIFNGHVDVVPAGDRRLWHSDPWQATIVNGRVYGRGALDMKGGLCCAIFAARAIAAAGVRLRG
RLVIQSVIGEEDGGLGTLAAILRGHTADAAIVAEPTELKVAPAQAGAHNFRLTVYGAAAHGCVREEGVSAIEKFAPLHQA
IIALERTRNERLRAADSSGLFSRYRTPNAICIGVVRAGEWASSEAEQLVAEGRYGIGVGEDPAIARTELEQTVAAAAAQD
PWLRDHPPMLEWWGGRFDPASTPMDSPVVQTLAACDQAVRGTPATFEGMTYGADMRLLVNVGGIPTVLYGPGDVRNAHRP
NESVAIVDLQTATRVLALTALRFCGYDEE

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=357, Percent_Identity=25.7703081232493, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789236, Length=423, Percent_Identity=23.1678486997636, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788816, Length=173, Percent_Identity=30.0578034682081, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649206, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 45919; Mature: 45919

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLHPIEQRVLSAINDDGLLKALADLVSIPSLDGTTAENEAQEAVAALLQSQSMTVDRW
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
EIDLPRLYAHPDCSWEVPRERALGVVGILGEDRGGRSLIFNGHVDVVPAGDRRLWHSDPW
ECCCCCEEECCCCCCCCCHHHCCEEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCCC
QATIVNGRVYGRGALDMKGGLCCAIFAARAIAAAGVRLRGRLVIQSVIGEEDGGLGTLAA
EEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHH
ILRGHTADAAIVAEPTELKVAPAQAGAHNFRLTVYGAAAHGCVREEGVSAIEKFAPLHQA
HHCCCCCCCEEEECCCCEEEECCCCCCCEEEEEEEECHHHCHHHHHHHHHHHHHHHHHHH
IIALERTRNERLRAADSSGLFSRYRTPNAICIGVVRAGEWASSEAEQLVAEGRYGIGVGE
HHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCC
DPAIARTELEQTVAAAAAQDPWLRDHPPMLEWWGGRFDPASTPMDSPVVQTLAACDQAVR
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GTPATFEGMTYGADMRLLVNVGGIPTVLYGPGDVRNAHRPNESVAIVDLQTATRVLALTA
CCCCCCCCEEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
LRFCGYDEE
HHHCCCCCC
>Mature Secondary Structure
MQHLHPIEQRVLSAINDDGLLKALADLVSIPSLDGTTAENEAQEAVAALLQSQSMTVDRW
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
EIDLPRLYAHPDCSWEVPRERALGVVGILGEDRGGRSLIFNGHVDVVPAGDRRLWHSDPW
ECCCCCEEECCCCCCCCCHHHCCEEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCCC
QATIVNGRVYGRGALDMKGGLCCAIFAARAIAAAGVRLRGRLVIQSVIGEEDGGLGTLAA
EEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHH
ILRGHTADAAIVAEPTELKVAPAQAGAHNFRLTVYGAAAHGCVREEGVSAIEKFAPLHQA
HHCCCCCCCEEEECCCCEEEECCCCCCCEEEEEEEECHHHCHHHHHHHHHHHHHHHHHHH
IIALERTRNERLRAADSSGLFSRYRTPNAICIGVVRAGEWASSEAEQLVAEGRYGIGVGE
HHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCC
DPAIARTELEQTVAAAAAQDPWLRDHPPMLEWWGGRFDPASTPMDSPVVQTLAACDQAVR
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GTPATFEGMTYGADMRLLVNVGGIPTVLYGPGDVRNAHRPNESVAIVDLQTATRVLALTA
CCCCCCCCEEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
LRFCGYDEE
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]