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The map label for this gene is yhcK [H]

Identifier: 222526038

GI number: 222526038

Start: 3442157

End: 3443926

Strand: Reverse

Name: yhcK [H]

Synonym: Chy400_2795

Alternate gene names: 222526038

Gene position: 3443926-3442157 (Counterclockwise)

Preceding gene: 222526039

Following gene: 222526037

Centisome position: 65.36

GC content: 53.95

Gene sequence:

>1770_bases
ATGAACCATGACACCTCTTCTGAACAATACATTCTGGTCACAGGTAGTGGACAGGTTCTGGCAGTAAGTGATACAGCTCA
ATCATTAATCCCTCATATCTCACCATTGCTACCTGATCTGATCAACGGAGCAGGCGAGGATACCGTCCTGCTCAACGGGC
GCACGTACCAGATACACCGACACCTTCTGAAGAGCGAGAGCGGCGAGTCATACGGTCTGCTCATCTCATTGCAACAGACA
AGCGCAGTGCAATCATCCGATCCCCGGCTCGGGGCAATTGCGCTCGCCCTTTCAGACAAATTAGAGATCAATCACGTTCT
GGAGAACGTTGTGCGCTTCGCGATGGATCTGCTCAACGCTGACGCTGGCGCACTTCCCATCTACGACCCGGATACCGACC
GTCTGTTGCCGGGGCATCTGGTCAATTTACCGGTTGATCTGATCGTACCGGTGATCGGGCAACGCCGTGGCCTCATGTGG
CAGATTGTCCATCAGGGAAGCTCAATTCTGATCGCCGATTATGCAGACCATCCGGCGGCACTACCGGAACTGGTACAGGT
CGGTGTACGTTCGTTACTGGCAACCCCTATCATTTACGGCAAAACACCGCTTGGCATCCTGGCGATGTATCGTTTGCGCA
ATGAACCATTTAGCGAAAGTGATCGCGAGTTACTCCAGGCAATCGCTCGCCAGACGGCTATCGCTCTCCAGAATGCCCGT
TTGTATCAGCGCGCCATTCGCAACGCCGACGAGCGCTTTGCGTTGTACCAGGCCAGTATCGAGATCGGTGCTACCCTTGA
TCTTGAGCAACTGTACCAGGTAATCTATCGCGCCACAACACGGTTGGTCAGCCATCAACGTTTCGTAATTGCGATCCCGA
CCGAAAACCGGATGGTTGAATATGTTCATATCGTGACCCCCACCGGACGACAGGCACCGCAACAGGTACCACTACACTGC
GGACTTGCCGGCTACGTCTTGCGTTTTGGCGTGTCACTACGACTATCCGGTGCACAGGCTCTCCCAGAACCGGCTGTCCA
ACTGCTGCCAGAAATTGAAGGTGAACTCGCCGACGGCTCGTTACTGGCAGCCCCGCTGATTGTTGGTGATCGGATCATCG
GTGCTCTCCTGGTGTGGAGCAACCACCACGATGCTTACACCATGGCCGATTTGAACGCGCTTGAACTGCTGGCAGCAACT
GTAGCCGTGGCGTTGCACAACGCATTTCGCTTTGCTCAGATCCAATCACAGGCAATCACCGATAATCTCACCGGGTTAGC
AAACCGGCGCCACTTCCTTCAGGTACTGCACCAGGAAATGGAACGTAACCGACGCTACCACACACCGGTCAGTATCGCGA
TGATCGACGTTGATCACTTCAAACAGATCAACGATACCTTTGGTCATATCGCCGGCGATTATGTACTCCGTGAAATTGCC
CGACGCTGTCGCCAACAATTGCGAGATGTTGATGTTCTGGCCCGCTACGGGGGAGAAGAATTTGGTCTTATCTTACCAGA
AACCACCTATGAACAGGCTTTGAAAGCTACGGAACGGCTACGAACAGTTCTGGCAACCACGCCGATCATGATTGATGGTC
GGCAGATCAATCCGACCATCAGCATCGGTGTTGCATCATTTCATCCAACCGTCTATCCCGATCCATCTTCACTGATTGCC
GACGCTGATCGCGCGCTCTACCTGGCCAAACAACAGGGGCGCAATCGCGTCTGCGGTGTACAGGAGCTGACCAACGATGC
CCAACCCTGA

Upstream 100 bases:

>100_bases
GCACAGCAGGCAGTAGACCGGCAGGCGCAGCATCAGAACACCTCAACCCCTGATCTACATGCCTCTATTTGGAGCTACCC
TGCTCCAACAGGTATGTTCT

Downstream 100 bases:

>100_bases
TTTTACCTACGTTCAACGCATCCTGACCAGTCGGGTCTATGATGTTGTCAAAGAGACCCCATTGCAACATGCGCCTCTTC
TCAGCGCCCGCCTGGGAGCA

Product: GAF sensor diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MNHDTSSEQYILVTGSGQVLAVSDTAQSLIPHISPLLPDLINGAGEDTVLLNGRTYQIHRHLLKSESGESYGLLISLQQT
SAVQSSDPRLGAIALALSDKLEINHVLENVVRFAMDLLNADAGALPIYDPDTDRLLPGHLVNLPVDLIVPVIGQRRGLMW
QIVHQGSSILIADYADHPAALPELVQVGVRSLLATPIIYGKTPLGILAMYRLRNEPFSESDRELLQAIARQTAIALQNAR
LYQRAIRNADERFALYQASIEIGATLDLEQLYQVIYRATTRLVSHQRFVIAIPTENRMVEYVHIVTPTGRQAPQQVPLHC
GLAGYVLRFGVSLRLSGAQALPEPAVQLLPEIEGELADGSLLAAPLIVGDRIIGALLVWSNHHDAYTMADLNALELLAAT
VAVALHNAFRFAQIQSQAITDNLTGLANRRHFLQVLHQEMERNRRYHTPVSIAMIDVDHFKQINDTFGHIAGDYVLREIA
RRCRQQLRDVDVLARYGGEEFGLILPETTYEQALKATERLRTVLATTPIMIDGRQINPTISIGVASFHPTVYPDPSSLIA
DADRALYLAKQQGRNRVCGVQELTNDAQP

Sequences:

>Translated_589_residues
MNHDTSSEQYILVTGSGQVLAVSDTAQSLIPHISPLLPDLINGAGEDTVLLNGRTYQIHRHLLKSESGESYGLLISLQQT
SAVQSSDPRLGAIALALSDKLEINHVLENVVRFAMDLLNADAGALPIYDPDTDRLLPGHLVNLPVDLIVPVIGQRRGLMW
QIVHQGSSILIADYADHPAALPELVQVGVRSLLATPIIYGKTPLGILAMYRLRNEPFSESDRELLQAIARQTAIALQNAR
LYQRAIRNADERFALYQASIEIGATLDLEQLYQVIYRATTRLVSHQRFVIAIPTENRMVEYVHIVTPTGRQAPQQVPLHC
GLAGYVLRFGVSLRLSGAQALPEPAVQLLPEIEGELADGSLLAAPLIVGDRIIGALLVWSNHHDAYTMADLNALELLAAT
VAVALHNAFRFAQIQSQAITDNLTGLANRRHFLQVLHQEMERNRRYHTPVSIAMIDVDHFKQINDTFGHIAGDYVLREIA
RRCRQQLRDVDVLARYGGEEFGLILPETTYEQALKATERLRTVLATTPIMIDGRQINPTISIGVASFHPTVYPDPSSLIA
DADRALYLAKQQGRNRVCGVQELTNDAQP
>Mature_589_residues
MNHDTSSEQYILVTGSGQVLAVSDTAQSLIPHISPLLPDLINGAGEDTVLLNGRTYQIHRHLLKSESGESYGLLISLQQT
SAVQSSDPRLGAIALALSDKLEINHVLENVVRFAMDLLNADAGALPIYDPDTDRLLPGHLVNLPVDLIVPVIGQRRGLMW
QIVHQGSSILIADYADHPAALPELVQVGVRSLLATPIIYGKTPLGILAMYRLRNEPFSESDRELLQAIARQTAIALQNAR
LYQRAIRNADERFALYQASIEIGATLDLEQLYQVIYRATTRLVSHQRFVIAIPTENRMVEYVHIVTPTGRQAPQQVPLHC
GLAGYVLRFGVSLRLSGAQALPEPAVQLLPEIEGELADGSLLAAPLIVGDRIIGALLVWSNHHDAYTMADLNALELLAAT
VAVALHNAFRFAQIQSQAITDNLTGLANRRHFLQVLHQEMERNRRYHTPVSIAMIDVDHFKQINDTFGHIAGDYVLREIA
RRCRQQLRDVDVLARYGGEEFGLILPETTYEQALKATERLRTVLATTPIMIDGRQINPTISIGVASFHPTVYPDPSSLIA
DADRALYLAKQQGRNRVCGVQELTNDAQP

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=41.7721518987342, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=37.8048780487805, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=41.3173652694611, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081881, Length=165, Percent_Identity=39.3939393939394, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=36.969696969697, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788381, Length=168, Percent_Identity=36.3095238095238, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=34.3023255813954, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787802, Length=167, Percent_Identity=32.3353293413174, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787541, Length=162, Percent_Identity=35.1851851851852, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788085, Length=184, Percent_Identity=33.1521739130435, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081977, Length=220, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87081974, Length=174, Percent_Identity=32.183908045977, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787056, Length=169, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=33.9506172839506, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 64981; Mature: 64981

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50887 GGDEF ; PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHDTSSEQYILVTGSGQVLAVSDTAQSLIPHISPLLPDLINGAGEDTVLLNGRTYQIHR
CCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
HLLKSESGESYGLLISLQQTSAVQSSDPRLGAIALALSDKLEINHVLENVVRFAMDLLNA
HHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
DAGALPIYDPDTDRLLPGHLVNLPVDLIVPVIGQRRGLMWQIVHQGSSILIADYADHPAA
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCH
LPELVQVGVRSLLATPIIYGKTPLGILAMYRLRNEPFSESDRELLQAIARQTAIALQNAR
HHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LYQRAIRNADERFALYQASIEIGATLDLEQLYQVIYRATTRLVSHQRFVIAIPTENRMVE
HHHHHHHCCHHHEEEEEEEEEECCEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEE
YVHIVTPTGRQAPQQVPLHCGLAGYVLRFGVSLRLSGAQALPEPAVQLLPEIEGELADGS
EEEEECCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHCCCCCCCC
LLAAPLIVGDRIIGALLVWSNHHDAYTMADLNALELLAATVAVALHNAFRFAQIQSQAIT
EEEHHHHHHHHHHEEHEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNLTGLANRRHFLQVLHQEMERNRRYHTPVSIAMIDVDHFKQINDTFGHIAGDYVLREIA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RRCRQQLRDVDVLARYGGEEFGLILPETTYEQALKATERLRTVLATTPIMIDGRQINPTI
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECEEECCEE
SIGVASFHPTVYPDPSSLIADADRALYLAKQQGRNRVCGVQELTNDAQP
EEEEEECCCCCCCCHHHHHHCCHHHEEEEHHCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MNHDTSSEQYILVTGSGQVLAVSDTAQSLIPHISPLLPDLINGAGEDTVLLNGRTYQIHR
CCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
HLLKSESGESYGLLISLQQTSAVQSSDPRLGAIALALSDKLEINHVLENVVRFAMDLLNA
HHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
DAGALPIYDPDTDRLLPGHLVNLPVDLIVPVIGQRRGLMWQIVHQGSSILIADYADHPAA
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCCCH
LPELVQVGVRSLLATPIIYGKTPLGILAMYRLRNEPFSESDRELLQAIARQTAIALQNAR
HHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LYQRAIRNADERFALYQASIEIGATLDLEQLYQVIYRATTRLVSHQRFVIAIPTENRMVE
HHHHHHHCCHHHEEEEEEEEEECCEECHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEE
YVHIVTPTGRQAPQQVPLHCGLAGYVLRFGVSLRLSGAQALPEPAVQLLPEIEGELADGS
EEEEECCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHCCCCCCCC
LLAAPLIVGDRIIGALLVWSNHHDAYTMADLNALELLAATVAVALHNAFRFAQIQSQAIT
EEEHHHHHHHHHHEEHEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNLTGLANRRHFLQVLHQEMERNRRYHTPVSIAMIDVDHFKQINDTFGHIAGDYVLREIA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RRCRQQLRDVDVLARYGGEEFGLILPETTYEQALKATERLRTVLATTPIMIDGRQINPTI
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECEEECCEE
SIGVASFHPTVYPDPSSLIADADRALYLAKQQGRNRVCGVQELTNDAQP
EEEEEECCCCCCCCHHHHHHCCHHHEEEEHHCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]