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The map label for this gene is glyQS [H]

Identifier: 222525927

GI number: 222525927

Start: 3314999

End: 3316618

Strand: Direct

Name: glyQS [H]

Synonym: Chy400_2682

Alternate gene names: 222525927

Gene position: 3314999-3316618 (Clockwise)

Preceding gene: 222525926

Following gene: 222525929

Centisome position: 62.92

GC content: 56.42

Gene sequence:

>1620_bases
GTGCCGGCTACATCACTTGATCAGATCGTGGCGCTGGCCAAGCGTCGTGGTTTTATCTTCCCCAGCAGCGAGATTTATGG
TGGGTTACAGGGTGTGTACGATTACGGCCCCCTTGGCGTGGAGTTGAAGAATAATATCATTGCTGATTGGTGGCGAACAA
ACGTCTACGAACGCGATGACATGGAAGGTCTTGATGCGGCCATTCTGATGAATCGGCTGGTCTGGAAATATTCCGGTCAT
GAAGAGACTTTCAACGATCCCCTGGTTGATTGCCGGAACTGTAAAATGCGCTGGCGGGCCGACCATATTCAGGGTGTTTG
TCCCAACTGTGGCTCACGCGATCTGACCGAACCGCGCCCCTTCAATATGATGTTTCGGACCCAGATCGGGCCGGTGGCTG
ACAGCGGCTCGTTTGCCTATTTGCGCCCGGAAACGGCGCAGGGGATTTTCGTCAACTTTGCCAATGTCCTGACGACCTCG
GCGCGGAAGTTGCCGTTTGGGATTGCGCAGGTTGGGAAAGCCTTCCGCAATGAGATCAATCCACGCAATTTTCTCTTCCG
GGTTCGCGAATTTGAGCAGATGGAGATCGAGTATTTCGTGATGCCCGGTACCGATGAAGAGTGGCATCAACGCTGGCTTG
AAGCCCGCCTGGCCTGGTGGGAGCAGATCGGTATTCCGCGTAGTCGGATTACTATCTACGATGTGCCGACTGCTGAGCTG
GCCCATTACTCGAAGCGGACGTTCGATTTGATGTATGAGTATCCCAACATCGGCGTGCAAGAGATTGAGGGGATTGCGAA
TCGAACTGACTACGATCTCGGCTCCCACAGCAAAGATCAGGCGCAGCTCAATCTGACCGCACGTGTGAATCACAACGAAG
ATAGCATTGCCCGCCTGACCTACTTCGATCAGGCCAGTGGTCGCCATGTGGTGCCTTACGTCATCGAGCCGTCGGCTGGG
GTTGGCCGGTGTATGCTGGCTGTGATGTGCGAGGGGTATGCAGAGGAGCTGACGAAAGCGATTCCCGGCGAGAAACTGGC
CGCGGTCGGTGAGGCGCTCAATGCGTTTCTCAAGTCGGTTGGTCGCAGCGAGAAGTTGAGCGGCGAAGCCCGCGATGCGA
TTCTGGCCCGTGGCGAAGAGCTTACCCAGGCGCTGGCCGAACGCTTACCTGAAGTTGAGCAGTTACTGGCGATGCCCGGT
GCCGATCAGATCGAACTGGGTAAGAAATTACGTGGCCAGGCGCAGCCATTGATCGACGAGCACTATCGCACAGTTCTGCG
CCTCAAGCCACGCCTGGCGCCGATCAAGGTTGCCGTCTTTCCGTTGAAGCGCAACCACGAAGAGATTGTCGCTACCGCCA
AAGCGGTGCGCCGACAGTTGCAGGCCGGCGGTAGGATGCGCACGATCTACGATGATACCGGTGCGATTGGCAAACTCTAC
CGTCGTCAGGACGAAATCGGGACACCGTTCTGTATCACGGTTGACTTCGATACGATTGGTCAGGGTAAAGACCCGGCCCT
GGCCGGTACCGTTACCGTCCGTGACCGCGACACTATGGCGCAGGAACGGGTACCAATTGCCGAATTAGAGGCGTATCTGC
GTGATAGAGTAAGCGCGTGA

Upstream 100 bases:

>100_bases
GGTCGCTAACCGGGGTGGAACCGCGCGTCAGAGTGATGCGTCCCCGGGCGCTTCGGCGCCCGGTTTTTTGTTGTCAGACG
TTGCGCAAAGGAGGAATATC

Downstream 100 bases:

>100_bases
CCGTTCGTAAAGACCCGACCCTGGCCGGTACCGTTACCGTCCGTGATCGCGACACTATGGCGCAGGAACGGGTACCAATT
GCCGAATTAGAGGCGTATCT

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MPATSLDQIVALAKRRGFIFPSSEIYGGLQGVYDYGPLGVELKNNIIADWWRTNVYERDDMEGLDAAILMNRLVWKYSGH
EETFNDPLVDCRNCKMRWRADHIQGVCPNCGSRDLTEPRPFNMMFRTQIGPVADSGSFAYLRPETAQGIFVNFANVLTTS
ARKLPFGIAQVGKAFRNEINPRNFLFRVREFEQMEIEYFVMPGTDEEWHQRWLEARLAWWEQIGIPRSRITIYDVPTAEL
AHYSKRTFDLMYEYPNIGVQEIEGIANRTDYDLGSHSKDQAQLNLTARVNHNEDSIARLTYFDQASGRHVVPYVIEPSAG
VGRCMLAVMCEGYAEELTKAIPGEKLAAVGEALNAFLKSVGRSEKLSGEARDAILARGEELTQALAERLPEVEQLLAMPG
ADQIELGKKLRGQAQPLIDEHYRTVLRLKPRLAPIKVAVFPLKRNHEEIVATAKAVRRQLQAGGRMRTIYDDTGAIGKLY
RRQDEIGTPFCITVDFDTIGQGKDPALAGTVTVRDRDTMAQERVPIAELEAYLRDRVSA

Sequences:

>Translated_539_residues
MPATSLDQIVALAKRRGFIFPSSEIYGGLQGVYDYGPLGVELKNNIIADWWRTNVYERDDMEGLDAAILMNRLVWKYSGH
EETFNDPLVDCRNCKMRWRADHIQGVCPNCGSRDLTEPRPFNMMFRTQIGPVADSGSFAYLRPETAQGIFVNFANVLTTS
ARKLPFGIAQVGKAFRNEINPRNFLFRVREFEQMEIEYFVMPGTDEEWHQRWLEARLAWWEQIGIPRSRITIYDVPTAEL
AHYSKRTFDLMYEYPNIGVQEIEGIANRTDYDLGSHSKDQAQLNLTARVNHNEDSIARLTYFDQASGRHVVPYVIEPSAG
VGRCMLAVMCEGYAEELTKAIPGEKLAAVGEALNAFLKSVGRSEKLSGEARDAILARGEELTQALAERLPEVEQLLAMPG
ADQIELGKKLRGQAQPLIDEHYRTVLRLKPRLAPIKVAVFPLKRNHEEIVATAKAVRRQLQAGGRMRTIYDDTGAIGKLY
RRQDEIGTPFCITVDFDTIGQGKDPALAGTVTVRDRDTMAQERVPIAELEAYLRDRVSA
>Mature_538_residues
PATSLDQIVALAKRRGFIFPSSEIYGGLQGVYDYGPLGVELKNNIIADWWRTNVYERDDMEGLDAAILMNRLVWKYSGHE
ETFNDPLVDCRNCKMRWRADHIQGVCPNCGSRDLTEPRPFNMMFRTQIGPVADSGSFAYLRPETAQGIFVNFANVLTTSA
RKLPFGIAQVGKAFRNEINPRNFLFRVREFEQMEIEYFVMPGTDEEWHQRWLEARLAWWEQIGIPRSRITIYDVPTAELA
HYSKRTFDLMYEYPNIGVQEIEGIANRTDYDLGSHSKDQAQLNLTARVNHNEDSIARLTYFDQASGRHVVPYVIEPSAGV
GRCMLAVMCEGYAEELTKAIPGEKLAAVGEALNAFLKSVGRSEKLSGEARDAILARGEELTQALAERLPEVEQLLAMPGA
DQIELGKKLRGQAQPLIDEHYRTVLRLKPRLAPIKVAVFPLKRNHEEIVATAKAVRRQLQAGGRMRTIYDDTGAIGKLYR
RQDEIGTPFCITVDFDTIGQGKDPALAGTVTVRDRDTMAQERVPIAELEAYLRDRVSA

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=617, Percent_Identity=30.3079416531605, Blast_Score=205, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI32564541, Length=236, Percent_Identity=41.5254237288136, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17554996, Length=236, Percent_Identity=41.5254237288136, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325338, Length=630, Percent_Identity=28.5714285714286, Blast_Score=173, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6319597, Length=474, Percent_Identity=29.1139240506329, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24664462, Length=604, Percent_Identity=31.1258278145695, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI21357965, Length=604, Percent_Identity=31.1258278145695, Blast_Score=202, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 60893; Mature: 60762

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50862 AA_TRNA_LIGASE_II ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATSLDQIVALAKRRGFIFPSSEIYGGLQGVYDYGPLGVELKNNIIADWWRTNVYERDD
CCCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCCCCCEEECCCEEHHHHHCCCCCCCC
MEGLDAAILMNRLVWKYSGHEETFNDPLVDCRNCKMRWRADHIQGVCPNCGSRDLTEPRP
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEECHHHHCCCCCCCCCCCCCCCCC
FNMMFRTQIGPVADSGSFAYLRPETAQGIFVNFANVLTTSARKLPFGIAQVGKAFRNEIN
CCEEEECCCCCCCCCCCEEEECCCCCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHCCC
PRNFLFRVREFEQMEIEYFVMPGTDEEWHQRWLEARLAWWEQIGIPRSRITIYDVPTAEL
HHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHH
AHYSKRTFDLMYEYPNIGVQEIEGIANRTDYDLGSHSKDQAQLNLTARVNHNEDSIARLT
HHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEE
YFDQASGRHVVPYVIEPSAGVGRCMLAVMCEGYAEELTKAIPGEKLAAVGEALNAFLKSV
EEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GRSEKLSGEARDAILARGEELTQALAERLPEVEQLLAMPGADQIELGKKLRGQAQPLIDE
CCCHHCCCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCHHHH
HYRTVLRLKPRLAPIKVAVFPLKRNHEEIVATAKAVRRQLQAGGRMRTIYDDTGAIGKLY
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHH
RRQDEIGTPFCITVDFDTIGQGKDPALAGTVTVRDRDTMAQERVPIAELEAYLRDRVSA
HHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PATSLDQIVALAKRRGFIFPSSEIYGGLQGVYDYGPLGVELKNNIIADWWRTNVYERDD
CCCHHHHHHHHHHHCCCCCCCHHHHCCHHHHCCCCCCCEEECCCEEHHHHHCCCCCCCC
MEGLDAAILMNRLVWKYSGHEETFNDPLVDCRNCKMRWRADHIQGVCPNCGSRDLTEPRP
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEECHHHHCCCCCCCCCCCCCCCCC
FNMMFRTQIGPVADSGSFAYLRPETAQGIFVNFANVLTTSARKLPFGIAQVGKAFRNEIN
CCEEEECCCCCCCCCCCEEEECCCCCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHCCC
PRNFLFRVREFEQMEIEYFVMPGTDEEWHQRWLEARLAWWEQIGIPRSRITIYDVPTAEL
HHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHH
AHYSKRTFDLMYEYPNIGVQEIEGIANRTDYDLGSHSKDQAQLNLTARVNHNEDSIARLT
HHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEE
YFDQASGRHVVPYVIEPSAGVGRCMLAVMCEGYAEELTKAIPGEKLAAVGEALNAFLKSV
EEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GRSEKLSGEARDAILARGEELTQALAERLPEVEQLLAMPGADQIELGKKLRGQAQPLIDE
CCCHHCCCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHCCCCCCHHHH
HYRTVLRLKPRLAPIKVAVFPLKRNHEEIVATAKAVRRQLQAGGRMRTIYDDTGAIGKLY
HHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHH
RRQDEIGTPFCITVDFDTIGQGKDPALAGTVTVRDRDTMAQERVPIAELEAYLRDRVSA
HHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA