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The map label for this gene is ruvA

Identifier: 222524813

GI number: 222524813

Start: 1960902

End: 1961489

Strand: Direct

Name: ruvA

Synonym: Chy400_1540

Alternate gene names: 222524813

Gene position: 1960902-1961489 (Clockwise)

Preceding gene: 222524811

Following gene: 222524816

Centisome position: 37.22

GC content: 54.59

Gene sequence:

>588_bases
ATGATTGCATCAATCCGCGGCATCATTCAGAGCATCGGTATCGACCACCTGATCGTCGAGACCGGTGGGGTGGGACTTCT
CATCTACGCTCCGCGTTCTACTTTGAATGCTGTTGGTCAGATCGGTAGTGAAACATTCCTCTACACCCTGCTCATTGTAC
GTGAAGACGCGCTGACATTATACGGTTTTAGCGATCCAGCTCAACGCAACCTGTTCGAGCAGTTGATTGGTGTCAGCGGA
GTAGGCCCCAAAATCGCCTTAAACCTGCTATCGAGTGGCTCTCCCGATGAGATACAAAAGAGTATTGCCGGTGGCGATAT
AGCACGCCTGGCACGAGTGCCAGGAATCGGCAAGAAGACTGCCGAACGGATTGTGCTGGAACTCCGGGGTAAGATCGATT
TGCGCCAGCTATCCGGCACGACTCCAGGCAACGTGAGCACTCTCGACCGTGAGCTGACCGACATCCTGATCAGTCTAGGG
TACAGCGCTACAGAAGCAGCCGCAGCAATTGCGGCCCTACCGGGAGATGCCCCGCCAACCCTGGAAGAGCGCTTACGACT
GGCATTACGCTATTTTGGTAGTGCCTGA

Upstream 100 bases:

>100_bases
ACATCCAAACTGAGCAAGCACCAGACTTATTGAGTAGAATGGCGAACGCATCTTCACCCGAAACCTCTCTTCAAACAATA
GTGTGTAAGGACTGCATAGT

Downstream 100 bases:

>100_bases
ACAGAAGCAAAACTGACCGTGCGCTCTTTTTCCGTATCAGGGTAAGCCAATCAATATCTCTGTCATTCGCCCACGGGACT
ACAGGTTTCCGATAGGAACA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MIASIRGIIQSIGIDHLIVETGGVGLLIYAPRSTLNAVGQIGSETFLYTLLIVREDALTLYGFSDPAQRNLFEQLIGVSG
VGPKIALNLLSSGSPDEIQKSIAGGDIARLARVPGIGKKTAERIVLELRGKIDLRQLSGTTPGNVSTLDRELTDILISLG
YSATEAAAAIAALPGDAPPTLEERLRLALRYFGSA

Sequences:

>Translated_195_residues
MIASIRGIIQSIGIDHLIVETGGVGLLIYAPRSTLNAVGQIGSETFLYTLLIVREDALTLYGFSDPAQRNLFEQLIGVSG
VGPKIALNLLSSGSPDEIQKSIAGGDIARLARVPGIGKKTAERIVLELRGKIDLRQLSGTTPGNVSTLDRELTDILISLG
YSATEAAAAIAALPGDAPPTLEERLRLALRYFGSA
>Mature_195_residues
MIASIRGIIQSIGIDHLIVETGGVGLLIYAPRSTLNAVGQIGSETFLYTLLIVREDALTLYGFSDPAQRNLFEQLIGVSG
VGPKIALNLLSSGSPDEIQKSIAGGDIARLARVPGIGKKTAERIVLELRGKIDLRQLSGTTPGNVSTLDRELTDILISLG
YSATEAAAAIAALPGDAPPTLEERLRLALRYFGSA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=36.4532019704434, Blast_Score=118, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_CHLAA (A9WA87)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001635035.1
- ProteinModelPortal:   A9WA87
- SMR:   A9WA87
- GeneID:   5828524
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1418
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK14604
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 20551; Mature: 20551

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASIRGIIQSIGIDHLIVETGGVGLLIYAPRSTLNAVGQIGSETFLYTLLIVREDALTL
CCCHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEE
YGFSDPAQRNLFEQLIGVSGVGPKIALNLLSSGSPDEIQKSIAGGDIARLARVPGIGKKT
ECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCHHH
AERIVLELRGKIDLRQLSGTTPGNVSTLDRELTDILISLGYSATEAAAAIAALPGDAPPT
HHHHHHHHCCCCEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
LEERLRLALRYFGSA
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIASIRGIIQSIGIDHLIVETGGVGLLIYAPRSTLNAVGQIGSETFLYTLLIVREDALTL
CCCHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEE
YGFSDPAQRNLFEQLIGVSGVGPKIALNLLSSGSPDEIQKSIAGGDIARLARVPGIGKKT
ECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCHHH
AERIVLELRGKIDLRQLSGTTPGNVSTLDRELTDILISLGYSATEAAAAIAALPGDAPPT
HHHHHHHHCCCCEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
LEERLRLALRYFGSA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA