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The map label for this gene is mhpF [C]

Identifier: 222524745

GI number: 222524745

Start: 1868135

End: 1869052

Strand: Direct

Name: mhpF [C]

Synonym: Chy400_1472

Alternate gene names: 222524745

Gene position: 1868135-1869052 (Clockwise)

Preceding gene: 222524744

Following gene: 222524746

Centisome position: 35.46

GC content: 55.12

Gene sequence:

>918_bases
ATGCAAATCGACAAAGTTAAAGTCGCCATCCTCGGTTCCGGCAATATAGGCACCGATTTGATGTACAAACTGCTGAAGCA
GCCGGGCAGAATGGAGCTGGCGCTCGTTGCAGGTATCGATCCGGCCTCTGAAGGGTTGGCGCGCGCCAGACAGATCGGTA
TTCCGACCGCAACTGACGGCATTGAATCGATTCTGGCCGATCCTGATATTCGTATCGTATTTGATGCCACCAGCGCGAAG
GCACACGTGCGCCACGCCAGGCTTTTGCGCGATCATGGACGCATCGCTATCGATTTGACACCGGCTGCACGGGGGCCGTA
TGTGGTTCCACCGGTCAATCTCGGTGAGCATCTTGAGGCACATAATGTGAACCTCATTACCTGTGGCGGACAGGCAACCA
TTCCGCTGGTTTATGCGGTGAGCAGGGTAACAGCCGTTCGCTATGCCGAGATGGTGAGCACCGTTGCGAGTCGTTCAGCC
GGGCCAGGCACACGCCAGAATATCGATGAGTTTACCTTTACCACAGCACGGGGCTTGGAAGCCATCGGCGGTGCCCGTGA
AGCGAAGGCGATTATTATTTTGAACCCGGCGCATCCACCGATTCTGATGCGGAATACCATCTACGTTGTGCCAGAGGGCG
ATTTTGATGAAGAAACCGTCCGCCAATCGGTGGCACAGATGGTCGCTGATGTACAACAGTATGTTCCCGGCTATCGGTTA
AAGAGTTTGCCTGTCATCGAACAACGATCAACGCCGTGGGGTGAGCGACCGGTCATCATTATGCTCCTGGAAGTTGAAGG
TGCAGGTGATTTTCTCCCAACCTATGCCGGGAATCTCGACATCATGACTGCCGCCGCACGACGGGTGGGTGAACTATTCG
CCGCACACCTCTTGTCGAAACTGGAGGTGACCGTATGA

Upstream 100 bases:

>100_bases
CCCACCGCTTTCGCAAGCATCGCGAACAATACACGCGCGCAATCGTTGAAGGTGCGCAACGTATCTCTGAGCGGTTGGGA
TACTATGGAGGAACATCTGC

Downstream 100 bases:

>100_bases
AACCACCACGGCTGACCGATACAACGCTCCGTGATGGCTCACATCCGATGCGTCATCAGTTTACCCGCCAGCAGGTAGCT
ACGATTGTCCAGGCTCTCGA

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQIDKVKVAILGSGNIGTDLMYKLLKQPGRMELALVAGIDPASEGLARARQIGIPTATDGIESILADPDIRIVFDATSAK
AHVRHARLLRDHGRIAIDLTPAARGPYVVPPVNLGEHLEAHNVNLITCGGQATIPLVYAVSRVTAVRYAEMVSTVASRSA
GPGTRQNIDEFTFTTARGLEAIGGAREAKAIIILNPAHPPILMRNTIYVVPEGDFDEETVRQSVAQMVADVQQYVPGYRL
KSLPVIEQRSTPWGERPVIIMLLEVEGAGDFLPTYAGNLDIMTAAARRVGELFAAHLLSKLEVTV

Sequences:

>Translated_305_residues
MQIDKVKVAILGSGNIGTDLMYKLLKQPGRMELALVAGIDPASEGLARARQIGIPTATDGIESILADPDIRIVFDATSAK
AHVRHARLLRDHGRIAIDLTPAARGPYVVPPVNLGEHLEAHNVNLITCGGQATIPLVYAVSRVTAVRYAEMVSTVASRSA
GPGTRQNIDEFTFTTARGLEAIGGAREAKAIIILNPAHPPILMRNTIYVVPEGDFDEETVRQSVAQMVADVQQYVPGYRL
KSLPVIEQRSTPWGERPVIIMLLEVEGAGDFLPTYAGNLDIMTAAARRVGELFAAHLLSKLEVTV
>Mature_305_residues
MQIDKVKVAILGSGNIGTDLMYKLLKQPGRMELALVAGIDPASEGLARARQIGIPTATDGIESILADPDIRIVFDATSAK
AHVRHARLLRDHGRIAIDLTPAARGPYVVPPVNLGEHLEAHNVNLITCGGQATIPLVYAVSRVTAVRYAEMVSTVASRSA
GPGTRQNIDEFTFTTARGLEAIGGAREAKAIIILNPAHPPILMRNTIYVVPEGDFDEETVRQSVAQMVADVQQYVPGYRL
KSLPVIEQRSTPWGERPVIIMLLEVEGAGDFLPTYAGNLDIMTAAARRVGELFAAHLLSKLEVTV

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=319, Percent_Identity=51.0971786833856, Blast_Score=297, Evalue=7e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_CHLAA (A9W9U2)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001634967.1
- ProteinModelPortal:   A9W9U2
- GeneID:   5828455
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1350
- HOGENOM:   HBG300125
- OMA:   GLEVIGG
- ProtClustDB:   PRK08300
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32852; Mature: 32852

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: BINDING 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDKVKVAILGSGNIGTDLMYKLLKQPGRMELALVAGIDPASEGLARARQIGIPTATDG
CCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHH
IESILADPDIRIVFDATSAKAHVRHARLLRDHGRIAIDLTPAARGPYVVPPVNLGEHLEA
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCHHH
HNVNLITCGGQATIPLVYAVSRVTAVRYAEMVSTVASRSAGPGTRQNIDEFTFTTARGLE
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AIGGAREAKAIIILNPAHPPILMRNTIYVVPEGDFDEETVRQSVAQMVADVQQYVPGYRL
HHCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KSLPVIEQRSTPWGERPVIIMLLEVEGAGDFLPTYAGNLDIMTAAARRVGELFAAHLLSK
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEVTV
HEECC
>Mature Secondary Structure
MQIDKVKVAILGSGNIGTDLMYKLLKQPGRMELALVAGIDPASEGLARARQIGIPTATDG
CCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHH
IESILADPDIRIVFDATSAKAHVRHARLLRDHGRIAIDLTPAARGPYVVPPVNLGEHLEA
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCHHH
HNVNLITCGGQATIPLVYAVSRVTAVRYAEMVSTVASRSAGPGTRQNIDEFTFTTARGLE
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AIGGAREAKAIIILNPAHPPILMRNTIYVVPEGDFDEETVRQSVAQMVADVQQYVPGYRL
HHCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KSLPVIEQRSTPWGERPVIIMLLEVEGAGDFLPTYAGNLDIMTAAARRVGELFAAHLLSK
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEVTV
HEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA