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The map label for this gene is hup [H]

Identifier: 222524004

GI number: 222524004

Start: 902662

End: 902937

Strand: Reverse

Name: hup [H]

Synonym: Chy400_0719

Alternate gene names: 222524004

Gene position: 902937-902662 (Counterclockwise)

Preceding gene: 222524005

Following gene: 222524002

Centisome position: 17.14

GC content: 57.97

Gene sequence:

>276_bases
ATGCAGAAGACCGATTTCATTAAGGCTGTGGCCGAGCGCGCAAAGGTTTCGCAGAAGGAGACGAAGCTGATTATCGATGC
CGCGCTCGAGGTGATCACCGAAGCATTAGCTCGTGGCGAGAAGGTGACGCTCACCGGTTTTGGGACGTTCGAGGTGCGTT
CGCGGCAGGCACGGGAAGGTGTCAATCCGCAGACCCGCGAGAAGATGCATATTCCCGCTACGAAGACCCCTGGCTTCAGC
GCCAGCAGCACCCTCAAAGAGGCTGTGCGAGGTTAA

Upstream 100 bases:

>100_bases
TTTATCGCATCAACAAGAGATACAGGTCTTGACAGATGCGGTATACTGCTTTCTGAAGAGATATTCAGGTAGGAGTGAAT
ATTTAAGGAGGACTGCACCG

Downstream 100 bases:

>100_bases
AGCTGCGGATAACGTTCCGTTTTGTCTTGCCGGTCAAAAAGAGTACGGTACAACCGTACTCTTTTTGCTTTGTCTCGAAG
GTATATCACACGTGGCAGCA

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MQKTDFIKAVAERAKVSQKETKLIIDAALEVITEALARGEKVTLTGFGTFEVRSRQAREGVNPQTREKMHIPATKTPGFS
ASSTLKEAVRG

Sequences:

>Translated_91_residues
MQKTDFIKAVAERAKVSQKETKLIIDAALEVITEALARGEKVTLTGFGTFEVRSRQAREGVNPQTREKMHIPATKTPGFS
ASSTLKEAVRG
>Mature_91_residues
MQKTDFIKAVAERAKVSQKETKLIIDAALEVITEALARGEKVTLTGFGTFEVRSRQAREGVNPQTREKMHIPATKTPGFS
ASSTLKEAVRG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=42.2222222222222, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=42.2222222222222, Blast_Score=75, Evalue=9e-16,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9960; Mature: 9960

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTDFIKAVAERAKVSQKETKLIIDAALEVITEALARGEKVTLTGFGTFEVRSRQAREG
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCC
VNPQTREKMHIPATKTPGFSASSTLKEAVRG
CCCCCCCCEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQKTDFIKAVAERAKVSQKETKLIIDAALEVITEALARGEKVTLTGFGTFEVRSRQAREG
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCC
VNPQTREKMHIPATKTPGFSASSTLKEAVRG
CCCCCCCCEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA