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The map label for this gene is 222523929

Identifier: 222523929

GI number: 222523929

Start: 787655

End: 788698

Strand: Direct

Name: 222523929

Synonym: Chy400_0640

Alternate gene names: NA

Gene position: 787655-788698 (Clockwise)

Preceding gene: 222523921

Following gene: 222523930

Centisome position: 14.95

GC content: 57.76

Gene sequence:

>1044_bases
ATGGCTGAATGGATGATCTACGGCGCCAACGGCTATACCGGACGACTGATCGCGCGTGCAGCAGTGCAGGCAGGTTTGCG
ACCACGGCTCGCCGGGCGCAATGCAACACAGATAACGGCGCTGGCAAATGAACTGCATCTACCCTTTACCATCTGCCGAT
TGGATGATGAAGCAGCCCTGCGTCGTGCGCTTGAAGGCATGCAGCTCGTTCTCCACTGCGCCGGCCCATTCCAGGAGACC
AGTGCGCCAATGGTGCAGGCATGTCTGAACAGTGGTGTCCACTATCTTGACATCACGGGTGAGATAAGTGTTTTTGAAGC
ACTGGCACGTCAGGATCAGACTGCCCGCCAGGCCGGAGTCATGCTTATGCCAGGGGTCGGCTTTGATGTCGTACCCTCCG
ATTGTCTGGCGGCGCATCTGGCACGTCGCCTACCGGGTGCGAACAATCTGGTGCTGGCATTTCAGGCGCTCGGCAGCATC
TCACGCGGCACAGCCATCACAATGCTGACCATGGCCCATCGCGGATGCGAACGGCGAGACGGGCGGCTTGTCAGCACACC
ACCACTCCATGAGGTGCGAACCTTTGATTTCGGGCGTGGACCACAACCGTGTGTGAGTATTCCGTGGGGCGATGTTGCTA
CGGCCTACTACACGACTGGTATTCCCAACATCAAGGTTTTTGTCGCCATTTCGCGCCGAAACCTGCCGTGGCTCGGCCTG
GTACGCGCCATACTTCCCCTGATCCACCTCAAACCAATCCGCACCAGTCTCCAGAACTGGCTACGCCATACGCTTGATGG
CCCGGATACCACAACACGGGCAAAAGGAAAGAGTATCATCGTCGGTGAAGTCACCGACAGAACCGGACAGCGAGTTACCG
GTCGGCTTATCGGGCCTGAAGGATATTCGCTTACGGTGGCAACAGCGTTGCTCATTGTGCGCCGTGTTCTGGCAGGTACT
TACGAGGCAGGTTTTCATACACCGGCAGGGTTGTATGGGCCAGATCTGATCTGTGAGGTGCCCGGAGTGCAGATAACAGG
TTGA

Upstream 100 bases:

>100_bases
TGTAGCAGACTGACGTACAACACGTGCCGGCAACGCTGCACCCGCCGGGATGGGTGATAATAGGAAGGTGGTACCGCAAC
GTCAATACGGAGCAACAACC

Downstream 100 bases:

>100_bases
TTGAAGGCATTATCTTGATCGGACTCGTGCTCCGCCTGAAGAGCACATTGCGCAGCCAGAAAGACGGAGCACCGGCTATG
ATGGGCGGAAACAGTAGCCA

Product: Saccharopine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAEWMIYGANGYTGRLIARAAVQAGLRPRLAGRNATQITALANELHLPFTICRLDDEAALRRALEGMQLVLHCAGPFQET
SAPMVQACLNSGVHYLDITGEISVFEALARQDQTARQAGVMLMPGVGFDVVPSDCLAAHLARRLPGANNLVLAFQALGSI
SRGTAITMLTMAHRGCERRDGRLVSTPPLHEVRTFDFGRGPQPCVSIPWGDVATAYYTTGIPNIKVFVAISRRNLPWLGL
VRAILPLIHLKPIRTSLQNWLRHTLDGPDTTTRAKGKSIIVGEVTDRTGQRVTGRLIGPEGYSLTVATALLIVRRVLAGT
YEAGFHTPAGLYGPDLICEVPGVQITG

Sequences:

>Translated_347_residues
MAEWMIYGANGYTGRLIARAAVQAGLRPRLAGRNATQITALANELHLPFTICRLDDEAALRRALEGMQLVLHCAGPFQET
SAPMVQACLNSGVHYLDITGEISVFEALARQDQTARQAGVMLMPGVGFDVVPSDCLAAHLARRLPGANNLVLAFQALGSI
SRGTAITMLTMAHRGCERRDGRLVSTPPLHEVRTFDFGRGPQPCVSIPWGDVATAYYTTGIPNIKVFVAISRRNLPWLGL
VRAILPLIHLKPIRTSLQNWLRHTLDGPDTTTRAKGKSIIVGEVTDRTGQRVTGRLIGPEGYSLTVATALLIVRRVLAGT
YEAGFHTPAGLYGPDLICEVPGVQITG
>Mature_346_residues
AEWMIYGANGYTGRLIARAAVQAGLRPRLAGRNATQITALANELHLPFTICRLDDEAALRRALEGMQLVLHCAGPFQETS
APMVQACLNSGVHYLDITGEISVFEALARQDQTARQAGVMLMPGVGFDVVPSDCLAAHLARRLPGANNLVLAFQALGSIS
RGTAITMLTMAHRGCERRDGRLVSTPPLHEVRTFDFGRGPQPCVSIPWGDVATAYYTTGIPNIKVFVAISRRNLPWLGLV
RAILPLIHLKPIRTSLQNWLRHTLDGPDTTTRAKGKSIIVGEVTDRTGQRVTGRLIGPEGYSLTVATALLIVRRVLAGTY
EAGFHTPAGLYGPDLICEVPGVQITG

Specific function: Involved in the reduction of the double bond between C-4 and C-5 during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis [H]

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=182, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644140, Length=166, Percent_Identity=31.3253012048193, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644142, Length=166, Percent_Identity=31.3253012048193, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356081, Length=166, Percent_Identity=31.3253012048193, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646278, Length=162, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 37459; Mature: 37328

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEWMIYGANGYTGRLIARAAVQAGLRPRLAGRNATQITALANELHLPFTICRLDDEAAL
CCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHH
RRALEGMQLVLHCAGPFQETSAPMVQACLNSGVHYLDITGEISVFEALARQDQTARQAGV
HHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCE
MLMPGVGFDVVPSDCLAAHLARRLPGANNLVLAFQALGSISRGTAITMLTMAHRGCERRD
EEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHCCCHHCC
GRLVSTPPLHEVRTFDFGRGPQPCVSIPWGDVATAYYTTGIPNIKVFVAISRRNLPWLGL
CEEECCCCCHHHEECCCCCCCCCEEECCCCCHHHHEEECCCCCEEEEEEEECCCCCHHHH
VRAILPLIHLKPIRTSLQNWLRHTLDGPDTTTRAKGKSIIVGEVTDRTGQRVTGRLIGPE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCC
GYSLTVATALLIVRRVLAGTYEAGFHTPAGLYGPDLICEVPGVQITG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEEECC
>Mature Secondary Structure 
AEWMIYGANGYTGRLIARAAVQAGLRPRLAGRNATQITALANELHLPFTICRLDDEAAL
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHH
RRALEGMQLVLHCAGPFQETSAPMVQACLNSGVHYLDITGEISVFEALARQDQTARQAGV
HHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCE
MLMPGVGFDVVPSDCLAAHLARRLPGANNLVLAFQALGSISRGTAITMLTMAHRGCERRD
EEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHCCCHHCC
GRLVSTPPLHEVRTFDFGRGPQPCVSIPWGDVATAYYTTGIPNIKVFVAISRRNLPWLGL
CEEECCCCCHHHEECCCCCCCCCEEECCCCCHHHHEEECCCCCEEEEEEEECCCCCHHHH
VRAILPLIHLKPIRTSLQNWLRHTLDGPDTTTRAKGKSIIVGEVTDRTGQRVTGRLIGPE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCC
GYSLTVATALLIVRRVLAGTYEAGFHTPAGLYGPDLICEVPGVQITG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA