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The map label for this gene is frc [H]

Identifier: 222523921

GI number: 222523921

Start: 780987

End: 781988

Strand: Direct

Name: frc [H]

Synonym: Chy400_0632

Alternate gene names: 222523921

Gene position: 780987-781988 (Clockwise)

Preceding gene: 222523920

Following gene: 222523929

Centisome position: 14.82

GC content: 55.59

Gene sequence:

>1002_bases
ATGCTGAAACTCTCGCATATCCTAGACGGCGTGTCAGTGGTTGAAATTGCCAGCTATATTCCAGGCCCCCTGTGTGGTGC
GCTGCTGGCCAGTCTCGGCGCAACGGTGGTGAAGATTGAGCGTCCAGGTGGCGACCCAATGCGTGCTTTCCCACCCTCTG
ATCATAGTGGTGAGCATCCGCTATTTGCGATCCTGAACCGCACAAAGCAATGCTACACGCTAAATTTGCGTCAACCCGCC
GACCAGACGAAGCTGTATGATCTGATCCGATCTGCTGATGTGTTGATCGATGGTCTCCGTCCCGGTGCGCTTGGTCGACT
TGGTCTGACAGATGAAACGTTGCTGGAAACCAATCCCCGATTGCTGATTGTGGCGATCAGTGGTTTACCACCTGAACACC
CTCATCGCCATATGGCGTTGCATGACCTGAATGCCCAGTCTCTTGCCGGTGTTCTCGCTGCAAGTGCAGATGATCCGCGC
ACACCAGGAGTGCATGCGGCTGATATGGTGAGTGGTCTGGCCGCCGCAGCCGGGGTGCTCGCAGGATTGTTAGCTCGCCA
CACGTCTAATCGCGGCGGGCGGATCGAAACATCACTGCTGAGTGCTGCGCAGTGGCTGAATATGCCTGCCCTTGCCCTGG
CCCTGGCCGGTCTCTTGACTGATGATACGCTCAACGGTCAATTCGCCTGTTATCGCCTCTACCAGACTGCCGACCACCGG
TATCTGGCCGTAGCAGCCCTGGAAGCGCATTTCTGGCAACGTGTCTGTACGGTTATCGAACGACCAGATTTAATCCCACT
CCAATATGATCGATCAGCACAACCAATGGTGATCAGCGCTCTGTCTGACATTTTTCGCCAACGACCGCTGCACGAATGGC
AGGCTATCTTTGATTCATTAGACACGTGTGTATCGCCCGTTTTGACTCCTCTGGACGCAGCGCGCGAACGTTCGATCATG
CCCGATGCGGGATTCGGCTCGCTATTTACGGTGCAGGATTGA

Upstream 100 bases:

>100_bases
CTTCGTTTGATCGGTTGAATGGATTTTTTACAACTTTTTTGACCATTCACGGTTGTGATACGATGAAGATGATCCGGGTA
AGCATGATTGATGAGGTGCT

Downstream 100 bases:

>100_bases
CCGGTTGCCCCTCTGCAAGTTGGGCAATCGCCGGTCGTAGTTCGGCAAACGTGATACCGCCCTCATACCGGGCCTGGATA
ATGCCATCGCGATCAACCAG

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLKLSHILDGVSVVEIASYIPGPLCGALLASLGATVVKIERPGGDPMRAFPPSDHSGEHPLFAILNRTKQCYTLNLRQPA
DQTKLYDLIRSADVLIDGLRPGALGRLGLTDETLLETNPRLLIVAISGLPPEHPHRHMALHDLNAQSLAGVLAASADDPR
TPGVHAADMVSGLAAAAGVLAGLLARHTSNRGGRIETSLLSAAQWLNMPALALALAGLLTDDTLNGQFACYRLYQTADHR
YLAVAALEAHFWQRVCTVIERPDLIPLQYDRSAQPMVISALSDIFRQRPLHEWQAIFDSLDTCVSPVLTPLDAARERSIM
PDAGFGSLFTVQD

Sequences:

>Translated_333_residues
MLKLSHILDGVSVVEIASYIPGPLCGALLASLGATVVKIERPGGDPMRAFPPSDHSGEHPLFAILNRTKQCYTLNLRQPA
DQTKLYDLIRSADVLIDGLRPGALGRLGLTDETLLETNPRLLIVAISGLPPEHPHRHMALHDLNAQSLAGVLAASADDPR
TPGVHAADMVSGLAAAAGVLAGLLARHTSNRGGRIETSLLSAAQWLNMPALALALAGLLTDDTLNGQFACYRLYQTADHR
YLAVAALEAHFWQRVCTVIERPDLIPLQYDRSAQPMVISALSDIFRQRPLHEWQAIFDSLDTCVSPVLTPLDAARERSIM
PDAGFGSLFTVQD
>Mature_333_residues
MLKLSHILDGVSVVEIASYIPGPLCGALLASLGATVVKIERPGGDPMRAFPPSDHSGEHPLFAILNRTKQCYTLNLRQPA
DQTKLYDLIRSADVLIDGLRPGALGRLGLTDETLLETNPRLLIVAISGLPPEHPHRHMALHDLNAQSLAGVLAASADDPR
TPGVHAADMVSGLAAAAGVLAGLLARHTSNRGGRIETSLLSAAQWLNMPALALALAGLLTDDTLNGQFACYRLYQTADHR
YLAVAALEAHFWQRVCTVIERPDLIPLQYDRSAQPMVISALSDIFRQRPLHEWQAIFDSLDTCVSPVLTPLDAARERSIM
PDAGFGSLFTVQD

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate. Essential enzyme for the bacterium survival, as it relies on oxalic acid as its sole source of energy [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI266456254, Length=313, Percent_Identity=31.3099041533546, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI42794625, Length=313, Percent_Identity=31.3099041533546, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI300863128, Length=317, Percent_Identity=26.4984227129338, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI300863124, Length=317, Percent_Identity=26.4984227129338, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI266458393, Length=271, Percent_Identity=29.8892988929889, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI266458397, Length=254, Percent_Identity=31.1023622047244, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI300863126, Length=307, Percent_Identity=23.1270358306189, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI42822893, Length=145, Percent_Identity=35.1724137931034, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI266458395, Length=145, Percent_Identity=35.1724137931034, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87082093, Length=199, Percent_Identity=29.6482412060301, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788717, Length=348, Percent_Identity=27.5862068965517, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786222, Length=239, Percent_Identity=27.1966527196653, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115535051, Length=316, Percent_Identity=31.3291139240506, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32564160, Length=317, Percent_Identity=31.5457413249211, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24585488, Length=309, Percent_Identity=31.0679611650485, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24648431, Length=197, Percent_Identity=32.48730964467, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 35902; Mature: 35902

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLSHILDGVSVVEIASYIPGPLCGALLASLGATVVKIERPGGDPMRAFPPSDHSGEHP
CCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCC
LFAILNRTKQCYTLNLRQPADQTKLYDLIRSADVLIDGLRPGALGRLGLTDETLLETNPR
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCC
LLIVAISGLPPEHPHRHMALHDLNAQSLAGVLAASADDPRTPGVHAADMVSGLAAAAGVL
EEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGLLARHTSNRGGRIETSLLSAAQWLNMPALALALAGLLTDDTLNGQFACYRLYQTADHR
HHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCC
YLAVAALEAHFWQRVCTVIERPDLIPLQYDRSAQPMVISALSDIFRQRPLHEWQAIFDSL
EEEHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
DTCVSPVLTPLDAARERSIMPDAGFGSLFTVQD
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MLKLSHILDGVSVVEIASYIPGPLCGALLASLGATVVKIERPGGDPMRAFPPSDHSGEHP
CCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCC
LFAILNRTKQCYTLNLRQPADQTKLYDLIRSADVLIDGLRPGALGRLGLTDETLLETNPR
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCC
LLIVAISGLPPEHPHRHMALHDLNAQSLAGVLAASADDPRTPGVHAADMVSGLAAAAGVL
EEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGLLARHTSNRGGRIETSLLSAAQWLNMPALALALAGLLTDDTLNGQFACYRLYQTADHR
HHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCC
YLAVAALEAHFWQRVCTVIERPDLIPLQYDRSAQPMVISALSDIFRQRPLHEWQAIFDSL
EEEHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
DTCVSPVLTPLDAARERSIMPDAGFGSLFTVQD
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150242; 2361939 [H]