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The map label for this gene is 222523543

Identifier: 222523543

GI number: 222523543

Start: 295152

End: 296318

Strand: Reverse

Name: 222523543

Synonym: Chy400_0249

Alternate gene names: NA

Gene position: 296318-295152 (Counterclockwise)

Preceding gene: 222523544

Following gene: 222523542

Centisome position: 5.62

GC content: 60.67

Gene sequence:

>1167_bases
ATGACCAATGTCTATATTGCAGGGATAGGGGCAACCGCCGTTGGCGAACATTATCGCCGTGGGCTGGCCGATCTGGTGAG
TGAGGCAGCGCGGGCGGCACTGGCGAGTGCGCCAGAGATTGCTCCGCATCAGATTGGAGCGCTCTATGTTGGCAGTGCCT
TCAGCGAGGAACTCTACGGTCAAAGCCAGGCTGGTGCGTATCTGGCCAGCATCCTGGGGCTGTCACCGTCGATTCCGGCA
TATCGAGTTGAGGCGGCTGGTGCCAGTGGGGCGCTGGCGTTGTACCAGGCGGTGCAGGCCGTGCAAAACGGCGTGGCGGT
GGCACTCGTGATCGGGGTTGATAAGGTCACCGATCATCTCGAAGATGAGATCGAGGCTGCGCAGGCAATGGCTGCCGACA
GCACTGAAGAGGCGTTGCACGGGGTGACATTGACGGCACAATGGGCGATGCTGATGCGCCGGTATATGCACGAGTATGGC
TATACCGCCGATGCATTTGCGCCGTTTCCGATCAATGCTCACGCCAACGGTGTGCACAACCCGCTGGCGCTGTACCGCTT
TGCGATTGATGCGAATAAATATCGGAAAGCCGCCCAGATCGCTTCACCGTTGAACATGCTCGATTGCAGTACGCTGGCCG
ACGGTGCTGCTGCGCTGATCGTTGTGGGTGAGCAGATTGCCCGTGAACTCGACCGCCCACGGATTCGCATTGCCGGTTCG
GCTGTTGCCACCGATCATCCGGCGCTCCATCGGCGGCGAAATCCGCTCGACTTGAGTGCAGCGCGGGCGAGTGCCCATAT
TGCACTTGGCCGGGCGCATCTGGGTGTTGGTGATGTGCAGGTGTGGGAATTGACCGATCCGCACGGAATTGCCGCCACCC
TTGCCTTAGAGGCAATTGGCTGCTACGAACCTGGAACAGCACCGCGCTATGCAGCCGAGGGCGCAATCACCCCAACCGGG
AAGACGCCAATTGCTACCTTCGGCGGTTACAAAGCACGCGGTGATGTGGGCGGCGCCAGTGGGGTCTATCAGGTGATCGA
ACTGACTCGCCAGCTTAGTGGGCAGGCCGGCCCGACCCAGGTGAGCAATGCCCGGATTGGTCTGAGCCAGTCACTCGGCG
GGATCGGGGCGACTGCTGTCAGCCATGTTCTGATTCGCGAATCGTAA

Upstream 100 bases:

>100_bases
TGTCGCGGCCTACCTGCAACGGGCAGTGATGATTGATTACGCCATCTATGCGAAGTGGCGCGGTAAGCTGGTGATGGGAT
AGTCTATCAGGAGTGCAACA

Downstream 100 bases:

>100_bases
GTTCACCCCTTCACAGAAATGGTTGCGTCAGGTACAATAAGGTTGTTTTCCGCCTGTTGTAACCAAGGAGCGCTCCCGTG
ATTCAGGAAATGGTCAATGG

Product: acetyl-CoA acetyltransferase-like protein

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTNVYIAGIGATAVGEHYRRGLADLVSEAARAALASAPEIAPHQIGALYVGSAFSEELYGQSQAGAYLASILGLSPSIPA
YRVEAAGASGALALYQAVQAVQNGVAVALVIGVDKVTDHLEDEIEAAQAMAADSTEEALHGVTLTAQWAMLMRRYMHEYG
YTADAFAPFPINAHANGVHNPLALYRFAIDANKYRKAAQIASPLNMLDCSTLADGAAALIVVGEQIARELDRPRIRIAGS
AVATDHPALHRRRNPLDLSAARASAHIALGRAHLGVGDVQVWELTDPHGIAATLALEAIGCYEPGTAPRYAAEGAITPTG
KTPIATFGGYKARGDVGGASGVYQVIELTRQLSGQAGPTQVSNARIGLSQSLGGIGATAVSHVLIRES

Sequences:

>Translated_388_residues
MTNVYIAGIGATAVGEHYRRGLADLVSEAARAALASAPEIAPHQIGALYVGSAFSEELYGQSQAGAYLASILGLSPSIPA
YRVEAAGASGALALYQAVQAVQNGVAVALVIGVDKVTDHLEDEIEAAQAMAADSTEEALHGVTLTAQWAMLMRRYMHEYG
YTADAFAPFPINAHANGVHNPLALYRFAIDANKYRKAAQIASPLNMLDCSTLADGAAALIVVGEQIARELDRPRIRIAGS
AVATDHPALHRRRNPLDLSAARASAHIALGRAHLGVGDVQVWELTDPHGIAATLALEAIGCYEPGTAPRYAAEGAITPTG
KTPIATFGGYKARGDVGGASGVYQVIELTRQLSGQAGPTQVSNARIGLSQSLGGIGATAVSHVLIRES
>Mature_387_residues
TNVYIAGIGATAVGEHYRRGLADLVSEAARAALASAPEIAPHQIGALYVGSAFSEELYGQSQAGAYLASILGLSPSIPAY
RVEAAGASGALALYQAVQAVQNGVAVALVIGVDKVTDHLEDEIEAAQAMAADSTEEALHGVTLTAQWAMLMRRYMHEYGY
TADAFAPFPINAHANGVHNPLALYRFAIDANKYRKAAQIASPLNMLDCSTLADGAAALIVVGEQIARELDRPRIRIAGSA
VATDHPALHRRRNPLDLSAARASAHIALGRAHLGVGDVQVWELTDPHGIAATLALEAIGCYEPGTAPRYAAEGAITPTGK
TPIATFGGYKARGDVGGASGVYQVIELTRQLSGQAGPTQVSNARIGLSQSLGGIGATAVSHVLIRES

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=405, Percent_Identity=26.4197530864197, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI302344760, Length=331, Percent_Identity=26.2839879154079, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI302344767, Length=325, Percent_Identity=26.1538461538462, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI302344762, Length=234, Percent_Identity=27.3504273504274, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537653, Length=390, Percent_Identity=26.9230769230769, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI19921506, Length=397, Percent_Identity=27.455919395466, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585051, Length=397, Percent_Identity=27.7078085642317, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 40274; Mature: 40143

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVYIAGIGATAVGEHYRRGLADLVSEAARAALASAPEIAPHQIGALYVGSAFSEELYG
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEECCHHHHHHCC
QSQAGAYLASILGLSPSIPAYRVEAAGASGALALYQAVQAVQNGVAVALVIGVDKVTDHL
CCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHH
EDEIEAAQAMAADSTEEALHGVTLTAQWAMLMRRYMHEYGYTADAFAPFPINAHANGVHN
HHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PLALYRFAIDANKYRKAAQIASPLNMLDCSTLADGAAALIVVGEQIARELDRPRIRIAGS
HHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECHHHHHHCCCCEEEEECC
AVATDHPALHRRRNPLDLSAARASAHIALGRAHLGVGDVQVWELTDPHGIAATLALEAIG
CCCCCCHHHHHCCCCCCHHHHHHHHHEEECHHHCCCCCEEEEEECCCCCHHHHHHHHHHC
CYEPGTAPRYAAEGAITPTGKTPIATFGGYKARGDVGGASGVYQVIELTRQLSGQAGPTQ
CCCCCCCCCCCCCCCCCCCCCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCC
VSNARIGLSQSLGGIGATAVSHVLIRES
CCCCCCCHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TNVYIAGIGATAVGEHYRRGLADLVSEAARAALASAPEIAPHQIGALYVGSAFSEELYG
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEECCHHHHHHCC
QSQAGAYLASILGLSPSIPAYRVEAAGASGALALYQAVQAVQNGVAVALVIGVDKVTDHL
CCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHHHHH
EDEIEAAQAMAADSTEEALHGVTLTAQWAMLMRRYMHEYGYTADAFAPFPINAHANGVHN
HHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PLALYRFAIDANKYRKAAQIASPLNMLDCSTLADGAAALIVVGEQIARELDRPRIRIAGS
HHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECHHHHHHCCCCEEEEECC
AVATDHPALHRRRNPLDLSAARASAHIALGRAHLGVGDVQVWELTDPHGIAATLALEAIG
CCCCCCHHHHHCCCCCCHHHHHHHHHEEECHHHCCCCCEEEEEECCCCCHHHHHHHHHHC
CYEPGTAPRYAAEGAITPTGKTPIATFGGYKARGDVGGASGVYQVIELTRQLSGQAGPTQ
CCCCCCCCCCCCCCCCCCCCCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCC
VSNARIGLSQSLGGIGATAVSHVLIRES
CCCCCCCHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]