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The map label for this gene is cofD [H]

Identifier: 222523512

GI number: 222523512

Start: 261027

End: 261983

Strand: Reverse

Name: cofD [H]

Synonym: Chy400_0218

Alternate gene names: 222523512

Gene position: 261983-261027 (Counterclockwise)

Preceding gene: 222523513

Following gene: 222523511

Centisome position: 4.97

GC content: 59.25

Gene sequence:

>957_bases
ATGATAGTTGTACTTTCCGGCGGCGTTGGTGCCGCTCGCTTTATCGAAGGGCTGGCAGCAGTTGTTGCCCCAGAACGGAT
CGCGGCTGTCGTCAATACCGGCGACGATATGGTGCTGCACGGCTTATATATCTCCCCCGATCTCGATATCGTCACCTGTA
CGCTGGCAGATGTGATTGACCGCAACCAGGGCTGGGGGATTGCCGGTGATACCGATGCCTGTATGCAATGGCTGGCCCGG
CTCGGCGCTCCTACCTGGTTTAAGCTCGGTGATCGCGATCTGGCGTTGCATATCTACCGGACGGCGCGGTTGCAGGCCGG
TGCGACCCTCTCGCAAGTCGCCGATGAGATTCGGCAGGCATTGGGTGTGGCTGTCTCAATCATCCCGATGAGTGATGATC
CGGCGCCTACCCACGTCCTTACCGATCAGGGCGAACTGCATTTTGAAGAGTATTTTGTCCGCGAGCGCTGTCAACCGGTC
GTACACGGCGTGCGCCTGCACGCTGCCGGCCCGGTTCGGCCAGCTCCTGCCTTGTTGCCTTTGCTAATGAGTGCAGAGGT
CATTATTATCGCGCCGAGCAATCCGGTGGTGAGTGTAGGGCCAATTCTGGCCATTCCTGAAGTGCGTACCACTCTGACGA
CAACGAATACGCCGGTGGTGGCAGTTAGTCCGATTGTTGGTGGCGCAGCAATCAAGGGTCCGGCTGTCCCACTGATGAAA
GCGGTTGGTCTCACCCCGACTGCGCTCGGTGTGGCCGAGACGTATGCCGACCTGATCGATGGGATCGTGATCGACACCAT
TGATGCGGAGCTGGCGCCGGCTATTCAGTCTCGCGGGATTGCAACGCTGGTTACCGACACAATCATGCGCGGTATGCCAG
AAAAGATGGCCCTGGCCCGTGCGACGCTGGAACTGGCCAGCCTCATTGCGCCGTCCACAGCGAGGTCGTTAGTGTGA

Upstream 100 bases:

>100_bases
GGCCCGGCGGCGACTGGCGAATCTGTTGTTCTAACGAACCCGATGATACCGGCGTGGTTGGATCACGCCGGTTTCCTTTT
GTAGACTCCGCAGCGTACCT

Downstream 100 bases:

>100_bases
TCGGTATTGTCATTCCCATCAAGCGTCTACACCTGGCGAAATCGCGCCTGATCGATCTGCTCGATCCGGCGGATCGCCAA
CAGCTCGTGGTGACAATGGT

Product: LPPG:FO 2-phospho-L-lactate transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MIVVLSGGVGAARFIEGLAAVVAPERIAAVVNTGDDMVLHGLYISPDLDIVTCTLADVIDRNQGWGIAGDTDACMQWLAR
LGAPTWFKLGDRDLALHIYRTARLQAGATLSQVADEIRQALGVAVSIIPMSDDPAPTHVLTDQGELHFEEYFVRERCQPV
VHGVRLHAAGPVRPAPALLPLLMSAEVIIIAPSNPVVSVGPILAIPEVRTTLTTTNTPVVAVSPIVGGAAIKGPAVPLMK
AVGLTPTALGVAETYADLIDGIVIDTIDAELAPAIQSRGIATLVTDTIMRGMPEKMALARATLELASLIAPSTARSLV

Sequences:

>Translated_318_residues
MIVVLSGGVGAARFIEGLAAVVAPERIAAVVNTGDDMVLHGLYISPDLDIVTCTLADVIDRNQGWGIAGDTDACMQWLAR
LGAPTWFKLGDRDLALHIYRTARLQAGATLSQVADEIRQALGVAVSIIPMSDDPAPTHVLTDQGELHFEEYFVRERCQPV
VHGVRLHAAGPVRPAPALLPLLMSAEVIIIAPSNPVVSVGPILAIPEVRTTLTTTNTPVVAVSPIVGGAAIKGPAVPLMK
AVGLTPTALGVAETYADLIDGIVIDTIDAELAPAIQSRGIATLVTDTIMRGMPEKMALARATLELASLIAPSTARSLV
>Mature_318_residues
MIVVLSGGVGAARFIEGLAAVVAPERIAAVVNTGDDMVLHGLYISPDLDIVTCTLADVIDRNQGWGIAGDTDACMQWLAR
LGAPTWFKLGDRDLALHIYRTARLQAGATLSQVADEIRQALGVAVSIIPMSDDPAPTHVLTDQGELHFEEYFVRERCQPV
VHGVRLHAAGPVRPAPALLPLLMSAEVIIIAPSNPVVSVGPILAIPEVRTTLTTTNTPVVAVSPIVGGAAIKGPAVPLMK
AVGLTPTALGVAETYADLIDGIVIDTIDAELAPAIQSRGIATLVTDTIMRGMPEKMALARATLELASLIAPSTARSLV

Specific function: Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F42

COG id: COG0391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002882
- InterPro:   IPR010115 [H]

Pfam domain/function: PF01933 UPF0052 [H]

EC number: NA

Molecular weight: Translated: 33223; Mature: 33223

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVLSGGVGAARFIEGLAAVVAPERIAAVVNTGDDMVLHGLYISPDLDIVTCTLADVID
CEEEEECCCCHHHHHHHHHHHHCHHHHEEEEECCCCEEEEEEEECCCCCEEEEEHHHHHC
RNQGWGIAGDTDACMQWLARLGAPTWFKLGDRDLALHIYRTARLQAGATLSQVADEIRQA
CCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEHHHHCCCHHHHHHHHHHHH
LGVAVSIIPMSDDPAPTHVLTDQGELHFEEYFVRERCQPVVHGVRLHAAGPVRPAPALLP
HCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHH
LLMSAEVIIIAPSNPVVSVGPILAIPEVRTTLTTTNTPVVAVSPIVGGAAIKGPAVPLMK
HHHCCCEEEEECCCCCEECCCEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHH
AVGLTPTALGVAETYADLIDGIVIDTIDAELAPAIQSRGIATLVTDTIMRGMPEKMALAR
HHCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
ATLELASLIAPSTARSLV
HHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MIVVLSGGVGAARFIEGLAAVVAPERIAAVVNTGDDMVLHGLYISPDLDIVTCTLADVID
CEEEEECCCCHHHHHHHHHHHHCHHHHEEEEECCCCEEEEEEEECCCCCEEEEEHHHHHC
RNQGWGIAGDTDACMQWLARLGAPTWFKLGDRDLALHIYRTARLQAGATLSQVADEIRQA
CCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEHHHHCCCHHHHHHHHHHHH
LGVAVSIIPMSDDPAPTHVLTDQGELHFEEYFVRERCQPVVHGVRLHAAGPVRPAPALLP
HCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCCHHHHH
LLMSAEVIIIAPSNPVVSVGPILAIPEVRTTLTTTNTPVVAVSPIVGGAAIKGPAVPLMK
HHHCCCEEEEECCCCCEECCCEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHH
AVGLTPTALGVAETYADLIDGIVIDTIDAELAPAIQSRGIATLVTDTIMRGMPEKMALAR
HHCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
ATLELASLIAPSTARSLV
HHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]