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The map label for this gene is cofC

Identifier: 222523511

GI number: 222523511

Start: 260413

End: 261030

Strand: Reverse

Name: cofC

Synonym: Chy400_0217

Alternate gene names: 222523511

Gene position: 261030-260413 (Counterclockwise)

Preceding gene: 222523512

Following gene: 222523509

Centisome position: 4.95

GC content: 59.22

Gene sequence:

>618_bases
GTGATCGGTATTGTCATTCCCATCAAGCGTCTACACCTGGCGAAATCGCGCCTGATCGATCTGCTCGATCCGGCGGATCG
CCAACAGCTCGTGGTGACAATGGTGCGCCATGTGATCACAACGGCGCGCCAGGCCGTTAGCTACCTGTCAATCCCGGCCC
GTATCTGGCTGGTCAGCCCTGAACCAACCCTGGCAACCGATAGCGAGGGGATTGAGTGGCTCCCCGATAACCAGGAAGAG
TTGAATGCAGCCCTGACCGAGGCGCGGCAGCGAATTCAGGCTGCCGGTGTGCAGATCATGATGGTTCTTGCCGGCGATTT
ACCCTTTGTGACAGTACGTGATCTGATCTTGCTCAGCGAAGCGCTCACCGACAACGACGTGGTGGTTGCCCCTGACCAGC
ATGGTCAAGGGACAAATGCGTTAGGGCTGCACCTGCCGTCGCAATTGCCGTTTGGCTTTGGGCCGGATAGTGCCGGCTAT
CATCTGCGCACGGCTGCCCGGCTCGGCTTGCGGGCCAGCCTGATCAGCACACCGACCCTGGCCTTCGATCTCGATGACGG
TGAGCGCTTGCAGCAATACTACCGCTGTATCGCCTCTTGTGATAATTTCGCCCGGTAG

Upstream 100 bases:

>100_bases
CCGACACAATCATGCGCGGTATGCCAGAAAAGATGGCCCTGGCCCGTGCGACGCTGGAACTGGCCAGCCTCATTGCGCCG
TCCACAGCGAGGTCGTTAGT

Downstream 100 bases:

>100_bases
TGCCGAACAGCGATAAAGCTATCAAGCGTATAAATGGCCAGTGCCGTCCAGATTGCGCCAAAGCCGATCAGTTGGGCAGT
TGAGAAGGGTTCGCCGTAGA

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGIVIPIKRLHLAKSRLIDLLDPADRQQLVVTMVRHVITTARQAVSYLSIPARIWLVSPEPTLATDSEGIEWLPDNQEE
LNAALTEARQRIQAAGVQIMMVLAGDLPFVTVRDLILLSEALTDNDVVVAPDQHGQGTNALGLHLPSQLPFGFGPDSAGY
HLRTAARLGLRASLISTPTLAFDLDDGERLQQYYRCIASCDNFAR

Sequences:

>Translated_205_residues
MIGIVIPIKRLHLAKSRLIDLLDPADRQQLVVTMVRHVITTARQAVSYLSIPARIWLVSPEPTLATDSEGIEWLPDNQEE
LNAALTEARQRIQAAGVQIMMVLAGDLPFVTVRDLILLSEALTDNDVVVAPDQHGQGTNALGLHLPSQLPFGFGPDSAGY
HLRTAARLGLRASLISTPTLAFDLDDGERLQQYYRCIASCDNFAR
>Mature_205_residues
MIGIVIPIKRLHLAKSRLIDLLDPADRQQLVVTMVRHVITTARQAVSYLSIPARIWLVSPEPTLATDSEGIEWLPDNQEE
LNAALTEARQRIQAAGVQIMMVLAGDLPFVTVRDLILLSEALTDNDVVVAPDQHGQGTNALGLHLPSQLPFGFGPDSAGY
HLRTAARLGLRASLISTPTLAFDLDDGERLQQYYRCIASCDNFAR

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFC_CHLAA (A9WC63)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001633845.1
- ProteinModelPortal:   A9WC63
- GeneID:   5824976
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_0203
- HOGENOM:   HBG699055
- OMA:   ARCTIRE
- ProtClustDB:   CLSK2476601
- HAMAP:   MF_02114
- InterPro:   IPR002835
- TIGRFAMs:   TIGR03552

Pfam domain/function: PF01983 DUF121

EC number: =2.7.7.68

Molecular weight: Translated: 22501; Mature: 22501

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIVIPIKRLHLAKSRLIDLLDPADRQQLVVTMVRHVITTARQAVSYLSIPARIWLVSP
CCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
EPTLATDSEGIEWLPDNQEELNAALTEARQRIQAAGVQIMMVLAGDLPFVTVRDLILLSE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHH
ALTDNDVVVAPDQHGQGTNALGLHLPSQLPFGFGPDSAGYHLRTAARLGLRASLISTPTL
HCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEE
AFDLDDGERLQQYYRCIASCDNFAR
EEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGIVIPIKRLHLAKSRLIDLLDPADRQQLVVTMVRHVITTARQAVSYLSIPARIWLVSP
CCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
EPTLATDSEGIEWLPDNQEELNAALTEARQRIQAAGVQIMMVLAGDLPFVTVRDLILLSE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHH
ALTDNDVVVAPDQHGQGTNALGLHLPSQLPFGFGPDSAGYHLRTAARLGLRASLISTPTL
HCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEE
AFDLDDGERLQQYYRCIASCDNFAR
EEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA