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The map label for this gene is nreC [H]

Identifier: 222523324

GI number: 222523324

Start: 25871

End: 26512

Strand: Direct

Name: nreC [H]

Synonym: Chy400_0025

Alternate gene names: 222523324

Gene position: 25871-26512 (Clockwise)

Preceding gene: 222523323

Following gene: 222523325

Centisome position: 0.49

GC content: 59.66

Gene sequence:

>642_bases
ATGAGCAGCATTCTCTTAGTTGATGATCACGCTGTGCTGCGTGCCGGTTTACGGCTTCTGCTCGACGGGCAACCCGATCT
GCGCGTTATCGGCGAGGCGGAAGATGTACGGACAGCCGTGGTGCAGGCCACTACTCTGCAGCCCGACCTGATCCTGCTCG
ATCTCAGCCTGACCGGGAGCAGTGGTCTGGCAGCCATTCCAGCCTTACGCGCAGTAGCTCCGCACAGTCGCATCCTGGTG
CTTACCATGCACGATGACGAAGGGTACGTGCGACAGGCTCTGGCTGCCGGTGCCAACGGCTATGTTCTGAAGCGTGCCGC
TGACGCCGAACTGATTGCGGCGATTCGGGCAGTTCTACGCGGGGAACTTTACATCCATCCAGCGCTAACCCGTCAGTTAC
TAGAGGATTTGCTTCCACAGACACCGGCTCTGAATCCCTGGGAAAGTCTGAGCGAGCGCGAACGCGAGGTTCTCTTGCTG
GTCGCCCGTGGCTACACTGCCGCCGAGATTGCCGAACAATTGAGCCTCAGTCCCAAAACGGTCGAAACCTATCGCACCCG
TGGCATGGAGAAACTTGGCCTGCGCTCGCGCGCCGCGCTGGTGCAGTACGCACTCAACCATAACCTGTTGACACCGACCT
GA

Upstream 100 bases:

>100_bases
GCAGCGCTTTTGAACGGCCAGCTCATCATCGAGTCGTCTCCCGGTAGTGGCACCACGTTGTACGTGGAAATTCCTTTAAC
GACCAGGCATGAGGAGTGCT

Downstream 100 bases:

>100_bases
TCCGGTTGCAAGCGGACAATGGCTGTCGGGAAAATCCTGACACAAGCCGATCAATAACCTGACTTTTCCTGCTACCGGTG
GCACCGGCACAGATGTAAAG

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSSILLVDDHAVLRAGLRLLLDGQPDLRVIGEAEDVRTAVVQATTLQPDLILLDLSLTGSSGLAAIPALRAVAPHSRILV
LTMHDDEGYVRQALAAGANGYVLKRAADAELIAAIRAVLRGELYIHPALTRQLLEDLLPQTPALNPWESLSEREREVLLL
VARGYTAAEIAEQLSLSPKTVETYRTRGMEKLGLRSRAALVQYALNHNLLTPT

Sequences:

>Translated_213_residues
MSSILLVDDHAVLRAGLRLLLDGQPDLRVIGEAEDVRTAVVQATTLQPDLILLDLSLTGSSGLAAIPALRAVAPHSRILV
LTMHDDEGYVRQALAAGANGYVLKRAADAELIAAIRAVLRGELYIHPALTRQLLEDLLPQTPALNPWESLSEREREVLLL
VARGYTAAEIAEQLSLSPKTVETYRTRGMEKLGLRSRAALVQYALNHNLLTPT
>Mature_212_residues
SSILLVDDHAVLRAGLRLLLDGQPDLRVIGEAEDVRTAVVQATTLQPDLILLDLSLTGSSGLAAIPALRAVAPHSRILVL
TMHDDEGYVRQALAAGANGYVLKRAADAELIAAIRAVLRGELYIHPALTRQLLEDLLPQTPALNPWESLSEREREVLLLV
ARGYTAAEIAEQLSLSPKTVETYRTRGMEKLGLRSRAALVQYALNHNLLTPT

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=37.2641509433962, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=36.2244897959184, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790102, Length=207, Percent_Identity=34.2995169082126, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788712, Length=200, Percent_Identity=32, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786747, Length=203, Percent_Identity=28.0788177339901, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=35.8695652173913, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23148; Mature: 23017

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2 ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSILLVDDHAVLRAGLRLLLDGQPDLRVIGEAEDVRTAVVQATTLQPDLILLDLSLTGS
CCCEEEECCHHHHHHCHHEEECCCCCEEEECCHHHHHHHHHHHEECCCCEEEEEEEECCC
SGLAAIPALRAVAPHSRILVLTMHDDEGYVRQALAAGANGYVLKRAADAELIAAIRAVLR
CCCHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
GELYIHPALTRQLLEDLLPQTPALNPWESLSEREREVLLLVARGYTAAEIAEQLSLSPKT
CCEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCHH
VETYRTRGMEKLGLRSRAALVQYALNHNLLTPT
HHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSILLVDDHAVLRAGLRLLLDGQPDLRVIGEAEDVRTAVVQATTLQPDLILLDLSLTGS
CCEEEECCHHHHHHCHHEEECCCCCEEEECCHHHHHHHHHHHEECCCCEEEEEEEECCC
SGLAAIPALRAVAPHSRILVLTMHDDEGYVRQALAAGANGYVLKRAADAELIAAIRAVLR
CCCHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
GELYIHPALTRQLLEDLLPQTPALNPWESLSEREREVLLLVARGYTAAEIAEQLSLSPKT
CCEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCHH
VETYRTRGMEKLGLRSRAALVQYALNHNLLTPT
HHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]