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The map label for this gene is pntAB [H]

Identifier: 221230901

GI number: 221230901

Start: 3152748

End: 3153086

Strand: Reverse

Name: pntAB [H]

Synonym: MLBr_02635

Alternate gene names: 221230901

Gene position: 3153086-3152748 (Counterclockwise)

Preceding gene: 221230902

Following gene: 221230900

Centisome position: 96.48

GC content: 53.39

Gene sequence:

>339_bases
ATGTATGACGAGTTATTGGCTAACTTGGCGATTCTGGTGTTGTCTGGGTTCGTCGGGTTCGCTGTGATCTCCAAAGTCCC
CAATACACTGCACACACCGCTGATGTCGGGCACCAATGCCATCCACGGTATTGTACTGCTCGGCGCACTGGTGGTGTTCG
GAGAAGTTGCGCAACCATCGCTTGCCGTGCAAATCATTCTGTTCGTCGCGGTCGTATTCGGCACGCTGAATGTTATCGGG
GGTTTTATCGTCACCGACCGGATGCTGGGTATGTTCAGGGGTAAGAAGAAGGCCTCGGCCGTCAAAACCGAAAAAGCAGC
AGAATCGGTGGCCAAATGA

Upstream 100 bases:

>100_bases
CTGTTGGACCTACTAATAAAGGATGGCAAGTTTGCCCCGGACTTTGACGACGAAGTCGTCGCGGAGTCATGTGTGACTCG
CGATCGAGAGGACTCCATAG

Downstream 100 bases:

>100_bases
ACTACTTCGTGATCGGCCTCTACATTCTTGCGTTCGCATTGTTCATCACCGGCTTGATGGGCCTGACCGGGCCCAGGACC
GCGGTGTCCGGCAACTTGAT

Product: pyridine transhydrogenase subunit alpha2

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha; Pyridine nucleotide transhydrogenase subunit alpha [H]

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MYDELLANLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGIVLLGALVVFGEVAQPSLAVQIILFVAVVFGTLNVIG
GFIVTDRMLGMFRGKKKASAVKTEKAAESVAK

Sequences:

>Translated_112_residues
MYDELLANLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGIVLLGALVVFGEVAQPSLAVQIILFVAVVFGTLNVIG
GFIVTDRMLGMFRGKKKASAVKTEKAAESVAK
>Mature_112_residues
MYDELLANLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGIVLLGALVVFGEVAQPSLAVQIILFVAVVFGTLNVIG
GFIVTDRMLGMFRGKKKASAVKTEKAAESVAK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=80, Percent_Identity=42.5, Blast_Score=66, Evalue=7e-12,
Organism=Homo sapiens, GI122939153, Length=80, Percent_Identity=42.5, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787887, Length=90, Percent_Identity=44.4444444444444, Blast_Score=77, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17550456, Length=84, Percent_Identity=41.6666666666667, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR016040
- InterPro:   IPR004571 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 11727; Mature: 11727

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDELLANLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGIVLLGALVVFGEVAQPS
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHH
LAVQIILFVAVVFGTLNVIGGFIVTDRMLGMFRGKKKASAVKTEKAAESVAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYDELLANLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGIVLLGALVVFGEVAQPS
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHH
LAVQIILFVAVVFGTLNVIGGFIVTDRMLGMFRGKKKASAVKTEKAAESVAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]